CAS 2307277-92-3

(R,R)-LRRK2-IN-7

Fórmula: C24H26N6O

InChI: InChI=1S/C24H26N6O/c1-22(2,31)18-5-8-29(12-18)20-10-21(27-15-26-20)30-19-9-17(4-3-16(19)11-28-30)24(14-25)13-23(24)6-7-23/h3-4,9-11,15,18,31H,5-8,12-13H2,1-2H3/t18-,24+/m1/s1

Chave InChI: JCQABEJXHUSDMF-KOSHJBKYSA-N

SMILES: CC(C)([C@@H]1CCN(C1)C2=NC=NC(=C2)N3C4=C(C=CC(=C4)[C@]5(CC56CC6)C#N)C=N3)O

Sinónimos:

• (R,R)-LRRK2-IN-7

(R,R)-LRRK2-IN-7

CAS: 2307277-92-3

(R,R)-LRRK2-IN-7 is an isomer of LRRK2-IN-7, a potent and selective LRRK2 kinase inhibitor with CNS penetrance. It exhibits an IC50 of 0.9 nM and demonstrates over 1000-fold selectivity compared to other kinases, ion channels, and CYP enzymes.

Fórmula: C₂₄H₂₆N₆O

Cor e Forma: Solid

Peso molecular: 414.50

Ref: TM-TYD-02662