CAS: 231277-92-2 - Lapatinib

Fórmula: C₂₉H₂₆ClFN₄O₄S

InChI: InChI=1S/C29H26ClFN4O4S/c1-40(36,37)12-11-32-16-23-7-10-27(39-23)20-5-8-26-24(14-20)29(34-18-33-26)35-22-6-9-28(25(30)15-22)38-17-19-3-2-4-21(31)13-19/h2-10,13-15,18,32H,11-12,16-17H2,1H3,(H,33,34,35)

Chave InChI: InChIKey=BCFGMOOMADDAQU-UHFFFAOYSA-N

SMILES: O=S(=O)(C)CCNCC=1OC(=CC1)C=2C=CC3=NC=NC(NC4=CC=C(OCC=5C=CC=C(F)C5)C(Cl)=C4)=C3C2

Sinónimos:

• 4-Quinazolinamine, N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[[[2-(methylsulfonyl)ethyl]amino]methyl]-2-furanyl]-
• 4-[[3-Chloro-4-(3-fluorobenzyloxy)phenyl]amino]-6-[5-[[(2-methanesulfonylethyl)amino]methyl]furan-2-yl]quinazoline
• Gd 2016
• Gsk 572016
• Gw 572016
• Gw 572016X
• Lapatinib base
• N-[3-Chloro-4-[(3-fluorobenzyl)oxy]phenyl]-6-[5-[[[2-(methanesulfonyl)ethyl]amino]methyl]-2-furyl]-4-quinazolinamine
• N-[3-Chloro-4-[(3-fluorobenzyl)oxy]phenyl]-6-[5-[[[2-(methylsulfonyl)ethyl]amino]methyl]-2-furyl]-4-quinazolinamine
• N-[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[(2-methylsulfonylethylamino)methyl]-2-furyl]quinazolin-4-amine
• N-[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[(2-methylsulfonylethylamino)methyl]furan-2-yl]quinazolin-4-amine
• N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[[[2-(methylsulfonyl)ethyl]amino]methyl]-2-furanyl]-4-Quinazolinamine
• N-[4-(3-Fluorobenzyloxy)-3-chlorophenyl]-6-[5-[[2-(methylsulfonyl)ethylamino]methyl]furan-2-yl]quinazolin-4-amine
• N-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methylsulfonyl)ethyl]amino}methyl)furan-2-yl]quinazolin-4-amine
• Tycerb
• Tyverb

Lapatinib

CAS: 231277-92-2

• Fórmula: C₂₉H₂₆ClFN₄O₄S
• Pureza: >98.0%(T)(HPLC)
• Cor e Forma: White to Light yellow powder to crystal
• Peso molecular: 581.06

Lapatinib

CAS: 231277-92-2

Lapatinib (GW572016) is an inhibitor of ErbB2 and EGFR (IC50=9.2/10.8 nM) with oral activity.

• Fórmula: C₂₉H₂₆ClFN₄O₄S
• Pureza: 99.03% - 99.89%
• Cor e Forma: Powder
• Peso molecular: 581.06

N-[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[[[2-(methylsulfonyl)ethyl]amino]methyl]-2-furanyl]-4-quinazolinamine

CAS: 231277-92-2

• Fórmula: C₂₉H₂₆ClFN₄O₄S
• Pureza: 99%
• Cor e Forma: Solid
• Peso molecular: 581.0575

Lapatinib

CAS: 231277-92-2388082-78-8

• Fórmula: C₂₉H₂₆ClFN₄O₄S
• Cor e Forma: Yellow Solid
• Peso molecular: 581.06

Lapatinib

CAS: 231277-92-2

• Fórmula: C₂₉H₂₆ClFN₄O₄S
• Pureza: ≥ 99.0%
• Cor e Forma: Pale yellow to yellow powder
• Peso molecular: 581.06

Lapatinib

CAS: 231277-92-2

Applications Lapatinib is a selective inhibitor of epidermal growth factor receptor (EGFR) and HER-2 tyrosine …

• Fórmula: C₂₉H₂₆ClFN₄O₄S
• Cor e Forma: Light Yellow
• Peso molecular: 581.06

Lapatinib base - Bio-X ™

CAS: 231277-92-2

Lapatinib is an antineoplastic agent used to treat breast and lung cancer. This drug is …

• Fórmula: C₂₉H₂₆ClFN₄O₄S
• Pureza: Min. 95%
• Cor e Forma: Powder
• Peso molecular: 581.06 g/mol

Lapatinib

CAS: 231277-92-2

Inhibitor of EGFR (ErbB1) and HER2 (ErbB2) receptor tyrosine kinases. Used for sensitization of HER2-overexpressing …

• Fórmula: C₂₉H₂₆ClFN₄O₄S
• Pureza: Min. 95%
• Cor e Forma: Slightly Yellow Powder
• Peso molecular: 581.06 g/mol