CAS 2351149-20-5

TGFβRII-IN-3

CAS: 2351149-20-5

TGFβRII-IN-3 (Compound 2r) is a selective inhibitor of the TGFβ type II receptor (TGFβ RII) with an IC50 of 4.1 μM. It inhibits TGFβ signaling by promoting protein degradation of TGFβ RII. Additionally, TGFβRI-IN-7 can block the transition from endothelial to mesenchymal states and inhibit cell migration, making it useful for cancer research.

Fórmula: C₂₇H₂₇F₃N₂O₂

Cor e Forma: Solid

Peso molecular: 468.51

Ref: TM-T209758