CAS 2375595-72-3

Fórmula: C19H22Cl2N6OS

InChI: InChI=1S/C19H20N6OS.2ClH/c1-24-5-7-25(8-6-24)11-2-3-13-14(10-11)22-17(21-13)15-16(20)12-4-9-27-19(12)23-18(15)26;;/h2-4,9-10H,5-8H2,1H3,(H,21,22)(H3,20,23,26);2*1H

Chave InChI: XESGZTINOLHKPH-UHFFFAOYSA-N

SMILES: CN1CCN(CC1)C2=CC3=C(C=C2)N=C(N3)C4=C(C5=C(NC4=O)SC=C5)N.Cl.Cl

4-Amino-5-(6-(4-methylpiperazin-1-yl)-1H-benzo[d]imidazol-2-yl)thieno[2,3-b]pyridin-6(7H)-one dihydrochloride

CAS: 2375595-72-3

4-Amino-5-(6-(4-methylpiperazin-1-yl)-1H-benzo[d]imidazol-2-yl)thieno[2,3-b]pyridin-6(7H)-one dihydrochloride

Fórmula: C₁₉H₂₂Cl₂N₆OS

Pureza: 95%

Peso molecular: 453.39

Ref: 54-OR1122142

4-Amino-5-(6-(4-methylpiperazin-1-yl)-1H-benzo[d]imidazol-2-yl)thieno[2,3-b]pyridin-6(7H)-one dihydrochloride

CAS: 2375595-72-3

Fórmula: C₁₉H₂₂Cl₂N₆OS

Pureza: 95%

Cor e Forma: Solid

Peso molecular: 453.3886

Ref: IN-DA01X79M

4-Amino-5-(6-(4-methylpiperazin-1-yl)-1H-benzo[d]imidazol-2-yl)thieno[2,3-b]pyridin-6(7H)-one dihydrochloride

CAS: 2375595-72-3

Fórmula: C₁₉H₂₂Cl₂N₆OS

Pureza: 99%

Peso molecular: 453.39

Ref: IN-DG01722107

HPK1-IN-2 dihydrochloride

CAS: 2375595-72-3

HPK1-IN-2 dihydrochloride, a potent and orally active inhibitor of hematopoietic progenitor kinase-1 (HPK1) with an IC 50 of less than 0.05 µM, demonstrates significant antitumor activity. It additionally exhibits inhibition of Lck kinase activity, with an IC 50 ranging from 0.05 to less than 0.5 µM, and Flt3 kinase activity, with an IC 50 of less than 0.05 µM [1].

Fórmula: C₁₉H₂₂Cl₂N₆OS

Cor e Forma: Solid

Peso molecular: 453.39

Ref: TM-T84714