CAS 2410056-27-6

Fórmula: C25H24FN5O2S

InChI: InChI=1S/C25H24FN5O2S/c1-33-21-5-3-2-4-17(21)19-14-34-22-13-28-25(31-23(19)22)30-16-6-7-18(20(26)12-16)24(32)29-15-8-10-27-11-9-15/h2-7,12-15,27H,8-11H2,1H3,(H,29,32)(H,28,30,31)

Chave InChI: NHLMMNCVSWYEIL-UHFFFAOYSA-N

SMILES: COC1=CC=CC=C1C2=CSC3=CN=C(N=C32)NC4=CC(=C(C=C4)C(=O)NC5CCNCC5)F

FAK inhibitor 6

CAS: 2410056-27-6

Compound 26F: potent enzyme inhibitor (IC50=28.2nM), low cytotoxicity (IC50=3.32μM), induces dose-dependent apoptosis in MDA-MB-231, blocks G0/G1 phase.

Fórmula: C₂₅H₂₄FN₅O₂S

Cor e Forma: Solid

Peso molecular: 477.55

Ref: TM-T63123