CAS 24390-14-5: Doxiciclina hiclato

Descrição: Doxiciclina hiclato é um antibiótico de amplo espectro pertencente à classe das tetraciclinas, usado principalmente para tratar várias infecções bacterianas, incluindo infecções do trato respiratório, infecções do trato urinário e certas condições de pele. É caracterizado pela sua capacidade de inibir a síntese de proteínas nas bactérias, ligando-se à subunidade ribossomal 30S, impedindo assim o crescimento e a reprodução dos microrganismos. Doxiciclina hiclato é um derivado semissintético da tetraciclina, que melhora sua estabilidade e absorção no trato gastrointestinal. A substância é tipicamente administrada por via oral e é conhecida por sua meia-vida relativamente longa, permitindo a dosagem uma ou duas vezes ao dia. Também é eficaz contra certas infecções protozoárias e é usada no tratamento da acne e como profilaxia para a malária. Efeitos colaterais comuns podem incluir distúrbios gastrointestinais, fotossensibilidade e efeitos potenciais no desenvolvimento de ossos e dentes em crianças. Devido à sua ampla atividade, Doxiciclina hiclato é uma ferramenta valiosa tanto na medicina humana quanto veterinária.

Fórmula: C₂₂H₂₄N₂O₈C₂H₆O·ClHH₂O

InChI: InChI=1S/C22H24N2O8.C2H6O.ClH.H2O/c1-7-8-5-4-6-9(25)11(8)16(26)12-10(7)17(27)14-15(24(2)3)18(28)13(21(23)31)20(30)22(14,32)19(12)29;1-2-3;;/h4-7,10,14-15,17,25,27-29,32H,1-3H3,(H2,23,31);3H,2H2,1H3;1H;1H2/t7-,10+,14+,15-,17-,22-;;;/m0.../s1

Chave InChI: InChIKey=JRNIHERUNQWMMW-WBYAVNBMSA-N

SMILES: Cl.O=C(N)C=1C(=O)C2(O)C(O)=C3C(=O)C=4C(O)=CC=CC4C(C)C3C(O)C2C(C1O)N(C)C.O.OCC

Sinónimos:

• (1S,3Z,4aS,11R,11aR,12S,12aR)-3-[amino(hydroxy)methylidene]-4a,6,7,12-tetrahydroxy-N,N,11-trimethyl-2,4,5-trioxo-1,2,3,4,4a,5,11,11a,12,12a-decahydrotetracen-1-aminium chloride
• (2E,4S,4aR,5S,5aR,6R,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5a,6,12a-tetrahydrotetracene-1,3,12(2H,4H,5H)-trione - ethanol (2:1) dihydrochloride hydrate
• (2Z,4S,4aR,5S,5aR,6R)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5a,6,12a-tetrahydrotetracene-1,3,12(2H,4H,5H)-trione hydrochloride
• (2Z,4S,4aR,5S,5aR,6R,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5a,6,12a-tetrahydrotetracene-1,3,12(2H,4H,5H)-trione - ethanol (2:1) dihydrochloride hydrate
• (4S,4Ar,5S,5Ar,6R,12As)-4-(Dimethylamino)-1,4,4A,5,5A,6,11,12A-Octahydro-3,5,10,12,12A-Pentahydroxy-6-Methyl-1,11-Dioxo-2-Naphthacenecarboxamide Hydrochloride
• (4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide-ethanol hydrochloride hydrate (2:1:2:1)
• 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, hydrochloride, (4S,4aR,5S,5aR,6R,12aS)-, compd. with ethanol, hydrate (2:2:1:1)
• 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, monohydrochloride, (4S,4aR,5S,5aR,6R,12aS)-, compd. with ethanol (2:1), monohydrate
• 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, monohydrochloride, [4S-(4α,4aα,5α,5aα,6α,12aα)]-, compd. with ethanol (2:1), monohydrate
• 2-Naphthacenecarboxamide, 4β-(dimethylamino)-1,4,4aβ,5,5aβ,6,11,12a-octahydro-3,5β,10,12,12aβ-pentahydroxy-6β-methyl-1,11-dioxo-, monohydrochloride, compd. with ethyl alc. (2:1), monohydrate
• 4-(Dimethylamino)-1,4,4A,5,5A,6,11,12A-Octahydro-3,5,10,12,12A-Pentahydroxy-6-Methyl-1,11-Dioxo-2-Na
• 4-(Dimethylamino)-3,5,10,12,12A-Pentahydroxy-6-Methyl-1,11-Dioxo-1,4,4A,5,5A,6,11,12A-Octahydrotetracene-2-Carboxamide
• 4-(Dimethylamino)-3,5,10,12,12A-Pentahydroxy-6-Methyl-1,11-Dioxo-1,4,4A,5,5A,6,11,12A-Octahydrotetracene-2-Carboxamide-Ethanol (2:1) Dihydrochloride Hydrate
• 6-Desoxy-5-hydroxytetracycline hydrochloride hemihydrate hemiethanolate
• Atridox
• BioPure MTAD
• Doryx
• Dox-T 100
• Doxitrat
• Doxy 100
• Doxycycline Hyclate
• Doxycycline Hyclate Monohydrate
• Doxycycline Hydrate
• Doxycycline Hydrochlocide
• Doxycycline Hydrochloride
• Doxycycline Hydrochloride Anhydrous
• Doxycycline Hydrochloride Hemiethanolate Hemihydrate
• Doxycycline hyclate COS
• Doxyprex
• Ethanol, compd. with (4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide monohydrochloride (1:2), monohydrate
• Ethanol, compd. with [4S-(4α,4aα,5α,5aα,6α,12aα)]-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide monohydrochloride (1:2), monohydrate
• Monodoks
• Periostat
• Tetraclean
• Wc 2031

Doxycycline Hyclate

CAS: 10592-13-9 24390-14-5564-25-0

• Fórmula: C₂₂H₂₄N₂O₈C₂H₆O·HClH₂O
• Pureza: >97.0%(HPLC)
• Cor e Forma: Light yellow to Amber to Dark green powder to crystal
• Peso molecular: 512.94

Doxycycline hyclate

CAS: 24390-14-5

Inhibits matrix metalloproteinases at subantimicrobial doses.Doxycycline hyclate is an antibacterial antibiotic, which is used in …

• Fórmula: C₄₆H₅₈Cl₂N₄O₁₈
• Cor e Forma: Powder or crystals or crystalline powder, Yellow
• Peso molecular: 1025.88

Doxycycline hyclate

CAS: 24390-14-5

• Fórmula: C₂₂H₂₄N₂O₈/ C₂₂H₂₅ClN₂O₈
• Pureza: 83.1% / 89.9%
• Cor e Forma: Yellow
• Peso molecular: 444.15327 / 480.12994

Doxycycline hyclate CRS

CAS: 24390-14-5

• Fórmula: C₄₆H₅₈Cl₂N₄O₁₈
• Cor e Forma: Crystalline Powder. Yellow. Powder.
• Peso molecular: 1025.875

Doxycycline for system suitability CRS

CAS: 24390-14-5

• Fórmula: C₄₆H₅₈Cl₂N₄O₁₈
• Cor e Forma: Crystalline Powder. Yellow. Powder.
• Peso molecular: 1025.875

Doxycycline Hyclate

CAS: 24390-14-5

Tetracyclines and their derivatives; salts thereof

• Fórmula: C₁₂H₂₄N₂O₈C₂H₆O·ClHH₂O
• Cor e Forma: Light Yellow Powder
• Peso molecular: 1025.89

2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, hydrochloride, (4S,4aR,5S,5aR,6R,12aS)-, compd. with ethanol, hydrate (2:2:1:1)

CAS: 24390-14-5

• Fórmula: C₄₆H₅₈Cl₂N₄O₁₈
• Pureza: 95%
• Cor e Forma: Solid
• Peso molecular: 1025.8747

Doxycycline hyclate

CAS: 24390-14-5

• Fórmula: C₂₂H₂₄N₂O₈·HCl·5H₂O·5C₂H₆O
• Pureza: 95.0 - 102.0 % (C22H25ClN2O8, anhydrous and ethanol free basis)
• Cor e Forma: Yellow, crystalline powder, hygroscopic
• Peso molecular: 512.94

Doxycycline (hyclate)

CAS: 24390-14-5

• Pureza: 99.17%
• Peso molecular: 512.9g/mol

Doxycycline hyclate

CAS: 24390-14-5

• Pureza: 99%
• Peso molecular: 544.982g/mol

Doxycycline hyclate

CAS: 24390-14-5

• Fórmula: C₂₂H₂₄N₂O₈·C₂H₆OClH·H₂O
• Cor e Forma: Neat
• Peso molecular: 1025.87

Doxycycline hyclate 100 µg/mL in Acetonitrile

CAS: 24390-14-5

• Fórmula: C₂₂H₂₄N₂O₈·C₂H₆OClH·H₂O
• Cor e Forma: Single Solution
• Peso molecular: 1025.87

Doxycycline hyclate, 98%

CAS: 24390-14-5

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. …

• Fórmula: C₄₆H₅₈Cl₂N₄O₁₈
• Pureza: 98%
• Cor e Forma: Powder, White to yellow
• Peso molecular: 1025.88

PharmaVetResiMix 5 Tetracyclines-v10 10 µg/mL in Methanol

CAS: 101342-45-4 14206-58-7 179471-95-5 2058-46-0 23313-80-6 24390-14-541411-66-9 64-72-2 64-73-3 64-75-5

• Cor e Forma: Mixture

Doxycycline Hyclate

CAS: 24390-14-5

• Fórmula: C₂₂H₂₄N₂O₈·C₂H₆OClH·H₂O
• Cor e Forma: Neat
• Peso molecular: 1025.87

Doxycycline (hyclate)

CAS: 24390-14-5

Doxycycline hyclate (WC2031) is a synthetic tetracycline derivative with similar antimicrobial activity. Doxycycline hyclate is …

• Fórmula: C₂₂H₂₄N₂O₈·HClC₂H₆OH₂O
• Pureza: 100% - 99.94%
• Cor e Forma: Yellow Crystallien Powder
• Peso molecular: 512.9

Doxycycline-d3 Hyclate (Major)

CAS: 24390-14-5

Applications Doxycycline-d3 Hyclate, is the labeled analogue of Doxycycline Hyclate (D561500), acting as an Antibacterial. …

• Fórmula: (C₂₂H₂₁D₃N₂O₈)• 2HCl•xH₂O•C₂H₆O
• Cor e Forma: Yellow
• Peso molecular: 2447.452364618

Doxycycline Hyclate

CAS: 24390-14-5

Applications Antibacterial. References Fabre, et al.: Chemotherapia, 11, 73 (1966), Goldenthal, et al.: Toxicol. Appl. …

• Fórmula: C₂₂H₂₄N₂O₈·C₂H₆OClH·H₂O
• Cor e Forma: Yellow
• Peso molecular: 1025.87

Doxycycline hyclate - Bio-X ™

CAS: 24390-14-5

Doxycycline is a tetracycline antibiotic that is used to treat a range of bacterial infections. …

• Fórmula: C₂₂H₂₄N₂O₈•HCl•(C₂H₆O)₀•(H₂O)₀
• Pureza: Min. 95 Area-%
• Cor e Forma: Powder
• Peso molecular: 512.94 g/mol

Doxycycline hyclate

CAS: 24390-14-5

Antibiotic; anti-protozoal; anti-helmintic; protein synthesis inhibitor

• Fórmula: C₂₂H₂₄N₂O₈•HCl•(C₂H₆O)₀•(H₂O)₀
• Pureza: Min. 95 Area-%
• Cor e Forma: Yellow Powder
• Peso molecular: 512.94 g/mol