CAS 2442519-59-5

Fórmula: C26H28ClF2N7

InChI: InChI=1S/C26H28ClF2N7/c1-16(2)36-9-7-35(8-10-36)6-5-30-17-11-25-24(31-14-17)4-3-23(33-25)19-15-32-34-26(19)18-12-20(27)22(29)13-21(18)28/h3-4,11-16,30H,5-10H2,1-2H3,(H,32,34)

Chave InChI: ATWFNMAJIPYWCA-UHFFFAOYSA-N

SMILES: CC(C)N1CCN(CC1)CCNC2=CC3=C(C=CC(=N3)C4=C(NN=C4)C5=CC(=C(C=C5F)F)Cl)N=C2

THRX-144644

CAS: 2442519-59-5

THRX-144644

Fórmula: C₂₆H₂₈ClF₂N₇

Peso molecular: 512.0

Ref: 54-BUP24672

THRX-144644

CAS: 2442519-59-5

THRX-144644 is a lung-selective ALK5 inhibitor with a biochemical IC50 value of 0.14 nM, can inhibit ALK5 in BEAS-2B cells, and targets the lung after inhaled administration in rats.

Fórmula: C₂₆H₂₈ClF₂N₇

Pureza: 98.06%

Cor e Forma: Solid

Peso molecular: 512

Ref: TM-T73016