CAS 24697-74-3

Leonurina

Descrição:

Leonurina, com o número CAS 24697-74-3, é um alcaloide que ocorre naturalmente, derivado principalmente da planta Leonurus cardiaca, comumente conhecida como erva-mãe. Este composto é caracterizado por suas características estruturais, que incluem um anel de piridina e um grupo hidroxila fenólico, contribuindo para sua atividade biológica. Leonurina é conhecido por suas potenciais propriedades farmacológicas, incluindo efeitos anti-inflamatórios, antioxidantes e neuroprotetores. Tem sido estudado por suas possíveis aplicações na medicina tradicional, particularmente no tratamento de distúrbios cardiovasculares e neurológicos. Além disso, Leonurina exibe efeitos sedativos leves, que podem ser benéficos para a ansiedade e alívio do estresse. Sua solubilidade em água é limitada, o que pode afetar sua biodisponibilidade e eficácia terapêutica. À medida que a pesquisa avança, todo o espectro de seus efeitos e mecanismos de ação está sendo explorado, destacando a importância dos compostos naturais no desenvolvimento de medicamentos e aplicações terapêuticas.

Fórmula: C₁₄H₂₁N₃O₅

InChI: InChI=1S/C14H21N3O5/c1-20-10-7-9(8-11(21-2)12(10)18)13(19)22-6-4-3-5-17-14(15)16/h7-8,18H,3-6H2,1-2H3,(H4,15,16,17)

Chave InChI: InChIKey=WNGSUWLDMZFYNZ-UHFFFAOYSA-N

SMILES: C(OCCCCNC(=N)N)(=O)C1=CC(OC)=C(O)C(OC)=C1

Sinónimos:

• 24697-74-3
• 4-Carbamimidamidobutyl 4-Hydroxy-3,5-Dimethoxybenzoate Hydrochloride Hydrate
• 4-Carbamimidamidobutyl-4-hydroxy-3,5-dimethoxybenzolcarboxylat
• 4-Guanidino-1-butanol Syringate
• 4-Hydroxy-3,5-dimethoxybenzoic Acid 4-[(Aminoiminomethyl)amino]butyl Ester
• 4-Hydroxy-3,5-dimethoxybenzoic Acid d-Guanidinobutyl Ester
• 4-[(Diaminomethylidene)Amino]Butyl 4-Hydroxy-3,5-Dimethoxybenzoate
• Benzoic Acid, 4-Hydroxy-3,5-Dimethoxy-, 4-[(Aminoiminomethyl)Amino]Butyl Ester
• Benzoic acid, 4-hydroxy-3,5-dimethoxy-, ester with (4-hydroxybutyl)guanidine
• Guanidine, (4-hydroxybutyl)-, 4-hydroxy-3,5-dimethoxybenzoate
• Guanidine, (4-hydroxybutyl)-, 4-hydroxy-3,5-dimethoxybenzoate (ester)
• Leonurin
• Leonurine
• Scm 198
• Syringic Acid d-Guanidinobutyl Ester

Leonurine

CAS: 24697-74-3

Leonurine

Fórmula: C₁₄H₂₁N₃O₅

Pureza: ≥98%

Peso molecular: 311.33

Ref: 54-BUP10292

4-Guanidinobutyl 4-Hydroxy-3,5-Dimethoxybenzoate

CAS: 24697-74-3

4-Guanidinobutyl 4-Hydroxy-3,5-Dimethoxybenzoate

Fórmula: C₁₄H₂₁N₃O₅

Pureza: 99+%

Peso molecular: 311.33

Ref: 54-OR1027299

Leonurine

CAS: 24697-74-3

Fórmula: C₁₄H₂₂CLN₃O₅

Peso molecular: 347.80

Ref: 7W-GY7471

Leonurine

CAS: 24697-74-3

Leonurine hydrochloride has anti-oxidative, anti-inflammatory, and antitumor activities, it exerts antidiabetic, cardiovascular, and bovine mastitis protection, it has an inhibitory effect on bleeding caused by incomplete abortion. Leonurine hydrochloride increases the expression levels of caspase-3, caspase-9 and Bax/Bcl-2, and it inhibits osteoclastogenesis and prevent osteoporosis associated with estrogen deficiency by inhibiting the NF-κB and PI3K/Akt signaling pathways.

Fórmula: C₁₄H₂₁N₃O₅

Pureza: 95%~99%

Peso molecular: 311.338

Ref: BP-BP0850

Leonurine

CAS: 24697-74-3

4-Guanidinobutyl 4-hydroxy-3,5-dimethoxybenzoate

Fórmula: C₁₄H₂₁N₃O₅

Pureza: 99+%

Peso molecular: 311.33

Ref: IN-DG165143

Leonurine

CAS: 24697-74-3

Leonurine (SCM-198) is an alkaloid that has been found in H. leonuri and with anti-oxidative and anti-inflammatory.

Fórmula: C₁₄H₂₂ClN₃O₅

Pureza: 98.55%

Cor e Forma: Solid

Peso molecular: 347.795

Ref: TM-T5S2102

Leonurine

Produto Controlado

CAS: 24697-74-3

Applications Leonurine is a pseudoalkaloid that has been isolated from Leonotis leonurus. A natural product with antioxidant, anti-inflammatory and cardioprotective properties for the treatment of wild variety of conditions including stroke, cerebral thrombosis and cardiovascular diseases.
References He, C., et al.: Zhongguo Linchuang Yaolixue Yu Zhiliaoxue, 18, 1419 (2013); Nsuala, B. N., et al.: J. Ethnopharmacol., 174, 520 (2015); Sun, Y., et al.; Eur. J. Drug Metabo. Pharmacokinet., 41, 423 (2016)

Fórmula: C₁₄H₂₁N₃O₅

Cor e Forma: Neat

Peso molecular: 311.33

Ref: TR-L329603

Leonurine

CAS: 24697-74-3

Leonurine is a polyphenolic compound that belongs to the group of natural compounds. It has been shown to have neuroprotective effects in vitro by inhibiting neuronal death at low doses. Leonurine also blocks the oxidative injury pathway, which may be related to its ability to inhibit apoptosis and reduce atherosclerotic lesion size in mice. In addition, leonurine inhibits the p-hydroxybenzoic acid (PHBA) oxidation pathway, which may contribute to its anti-inflammatory activities. Leonurine binds with high affinity and specificity to toll-like receptor 4 (TLR4), which may be related to its immunosuppressive properties.

Pureza: Min. 95%

Ref: 3D-FL73876

Leonurine

CAS: 24697-74-3

Fórmula: C₁₄H₂₁N₃O₅

Pureza: %

Cor e Forma: Solid

Peso molecular: 311.3336

Ref: IN-DA002P1O