CAS 2490599-18-1

Fórmula: C43H46F3N7O7S

InChI: InChI=1S/C43H46F3N7O7S/c1-26-38(61-25-50-26)29-7-5-27(6-8-29)21-47-40(56)35-19-31(54)22-53(35)41(57)39(42(2,3)4)52-37(55)23-58-17-18-59-32-13-9-28(10-14-32)34-20-36(49-24-48-34)51-30-11-15-33(16-12-30)60-43(44,45)46/h5-16,20,24-25,31,35,39,54H,17-19,21-23H2,1-4H3,(H,47,56)(H,52,55)(H,48,49,51)/t31-,35+,39-/m1/s1

Chave InChI: ONDVWISBMHHLGZ-SBJIGXGQSA-N

SMILES: CC1=C(SC=N1)C2=CC=C(C=C2)CNC(=O)[C@@H]3C[C@H](CN3C(=O)[C@H](C(C)(C)C)NC(=O)COCCOC4=CC=C(C=C4)C5=CC(=NC=N5)NC6=CC=C(C=C6)OC(F)(F)F)O

GMB-475

CAS: 2490599-18-1

GMB-475

Fórmula: C₄₃H₄₆F₃N₇O₇S

Pureza: 99.5%

Peso molecular: 861.93

Ref: 54-BUP08635

GMB-475

CAS: 2490599-18-1

Fórmula: C₄₃H₄₆F₃N₇O₇S

Pureza: 99%

Cor e Forma: Solid

Peso molecular: 861.9282

Ref: IN-DA01V70P

(2S,4R)-1-((S)-3,3-Dimethyl-2-(2-(2-(4-(6-((4-(trifluoromethoxy)phenyl)amino)pyrimidin-4-yl)phenoxy)ethoxy)acetamido)butanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide

CAS: 2490599-18-1

(2S,4R)-1-((S)-3,3-Dimethyl-2-(2-(2-(4-(6-((4-(trifluoromethoxy)phenyl)amino)pyrimidin-4-yl)phenoxy)ethoxy)acetamido)butanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide

Fórmula: C₄₃H₄₆F₃N₇O₇S

Pureza: 99%

Peso molecular: 861.93

Ref: IN-DG01190012

GMB-475

CAS: 2490599-18-1

GMB-475, a PROTAC-based BCR-ABL1 inhibitor, tackles drug resistance by promoting VHL-mediated degradation.

Fórmula: C₄₃H₄₆F₃N₇O₇S

Pureza: 99.64% - 99.89%

Cor e Forma: Solid

Peso molecular: 861.928

Ref: TM-T8488

GMB-475

CAS: 2490599-18-1

Pureza: 99%

Peso molecular: 861.9400024

Ref: 10-F840929