CAS 2516232-89-4

Fórmula: C19H19NO3S

InChI: InChI=1S/C19H19NO3S/c21-18(22)19(10-5-11-19)24-17-9-4-2-7-15(17)20-12-13-23-16-8-3-1-6-14(16)20/h1-4,6-9H,5,10-13H2,(H,21,22)

Chave InChI: KPGMCSIAAULVQO-UHFFFAOYSA-N

SMILES: C1CC(C1)(C(=O)O)SC2=CC=CC=C2N3CCOC4=CC=CC=C43

URAT1-IN-14

CAS: 2516232-89-4

URAT1-IN-14 is a potent and orally active inhibitor of uric acid transporter 1 (URAT1). It demonstrates an IC50 value of 0.72 μM for inhibiting human URAT1 in HEK293 cells and exhibits low cytotoxicity in Hep-G2 cells. URAT1-IN-14 reduces uric acid levels in a hyperuricemia mouse model and is applicable in research on hyperuricemia and gout.

Fórmula: C₁₉H₁₉NO₃S

Cor e Forma: Solid

Peso molecular: 341.42

Ref: TM-T212313