CAS 2639542-22-4

Fórmula: C29H28FN5O

InChI: InChI=1S/C29H28FN5O/c1-29(36,23-10-12-35(2)13-11-23)27-9-7-22-18-32-28(16-26(22)33-27)34-25-8-6-21(15-24(25)30)20-5-3-4-19(14-20)17-31/h3-9,14-16,18,23,36H,10-13H2,1-2H3,(H,32,34)/t29-/m1/s1

Chave InChI: KKNXJZMTIWJEEF-GDLZYMKVSA-N

SMILES: C[C@@](C1CCN(CC1)C)(C2=NC3=CC(=NC=C3C=C2)NC4=C(C=C(C=C4)C5=CC=CC(=C5)C#N)F)O

CDK5-IN-2

CAS: 2639542-22-4

CDK5-IN-2 (compound 15) is a highly selective CDK5 inhibitor that acts on CDK5/p25 (IC50: 0.2 nM) and CDK2/CycA (IC50: 23 nM).

Fórmula: C₂₉H₂₈FN₅O

Cor e Forma: Solid

Peso molecular: 481.56

Ref: TM-T63184