CAS 2648641-36-3

TPX-0131

CAS: 2648641-36-3

Ref: IN-DA0221Q6

Zotizalkib

CAS: 2648641-36-3

Zotizalkib

Fórmula: C₂₁H₂₀F₃N₅O₃

Pureza: ≥98%

Peso molecular: 447.41

Ref: 54-BUP13835

Zotizalkib

CAS: 2648641-36-3

TPX-0131: potent, selective, CNS-ready, oral ALK inhibitor (WT IC50: 1.4nM, G1202R/L1196M IC50: 0.3nM) with robust antitumor effects.

Fórmula: C₂₁H₂₀F₃N₅O₃

Pureza: 99.98%

Cor e Forma: Solid

Peso molecular: 447.41

Ref: TM-T9414

TPX0131

CAS: 2648641-36-3

TPX0131 is a recombinant human anti-IL8 antibody. TPX0131 has been shown to inhibit IL8 induced neutrophil chemotaxis and to block the IL8 receptor. TPX0131 also blocks the activation of NF-κB, a transcription factor involved in inflammation, and inhibits IL8 induced expression of adhesion molecules on endothelial cells. The affinity of TPX0131 for IL8 is low (Kd=1.5 nM) and it has high purity (>98%).

Fórmula: C₂₁H₂₀F₃N₅O₃

Pureza: Min. 95%

Peso molecular: 447.4 g/mol

Ref: 3D-FT181395