CAS 2728780-74-1

Fórmula: C31H37ClFN5O5

InChI: InChI=1S/C31H37ClFN5O5/c1-30(29(41)42)8-4-5-19(30)28(40)37-12-7-18-20(32)13-21(33)27(43-16-22-23-6-2-3-11-38(23)35-34-22)26(18)24(37)15-36-17-31(9-10-31)14-25(36)39/h13,19,24H,2-12,14-17H2,1H3,(H,41,42)/t19-,24+,30-/m0/s1

Chave InChI: WZPHPAGNPBBHKV-ULPUPHRNSA-N

SMILES: C[C@@]1(CCC[C@H]1C(=O)N2CCC3=C(C=C(C(=C3[C@H]2CN4CC5(CC5)CC4=O)OCC6=C7CCCCN7N=N6)F)Cl)C(=O)O

Nrf2 activator-6

CAS: 2728780-74-1

Nrf2 activator-6, a tetrahydroisoquinoline, inhibits Kelch-Nrf2 at 5 nM IC50 (WO2021214470A1).

Fórmula: C₃₁H₃₇ClFN₅O₅

Cor e Forma: Solid

Peso molecular: 614.11

Ref: TM-T72697