CAS 2759420-43-2

Fórmula: C49H55FN6O9

InChI: InChI=1S/C49H55FN6O9/c1-30(31-5-7-32(8-6-31)37-17-21-51-40-14-9-33(50)29-39(37)40)46(59)53-34-10-12-35(13-11-34)65-36-18-23-55(24-19-36)44(58)20-25-63-27-28-64-26-22-52-41-4-2-3-38-45(41)49(62)56(48(38)61)42-15-16-43(57)54-47(42)60/h2-4,9-14,17,21,29-32,36,42,52H,5-8,15-16,18-20,22-28H2,1H3,(H,53,59)(H,54,57,60)/t30-,31?,32?,42?/m1/s1

Chave InChI: PLYOHMQINGIYDN-LVMIGYEDSA-N

SMILES: C[C@H](C1CCC(CC1)C2=C3C=C(C=CC3=NC=C2)F)C(=O)NC4=CC=C(C=C4)OC5CCN(CC5)C(=O)CCOCCOCCNC6=CC=CC7=C6C(=O)N(C7=O)C8CCC(=O)NC8=O

NU223612

CAS: 2759420-43-2

"NU223612 is a potent IDO1-degrading PROTAC with Kd 640 nM, binds CRBN at 290 nM, and crosses the BBB."

Fórmula: C₄₉H₅₅FN₆O₉

Cor e Forma: Solid

Peso molecular: 890.99

Ref: TM-T74992