CAS 2849535-96-0

Fórmula: C21H23NO4

InChI: InChI=1S/C21H23NO4/c1-12(2)9-13(11-23)22-8-7-16-17(10-22)26-21-15-6-4-3-5-14(15)19(24)20(25)18(16)21/h3-6,12-13,23H,7-11H2,1-2H3/t13-/m0/s1

Chave InChI: YKVUDUKZQAMEHP-ZDUSSCGKSA-N

SMILES: CC(C)C[C@@H](CO)N1CCC2=C(C1)OC3=C2C(=O)C(=O)C4=CC=CC=C43

STAT3-IN-35

CAS: 2849535-96-0

STAT3-IN-35 is a STAT3 inhibitor that binds to the SH2 domain. This compound inhibits the phosphorylation of STAT3 and exhibits antiproliferative activity in triple-negative breast cancer (TNBC) cell lines. Additionally, STAT3-IN-35 has demonstrated toxicity and potent antitumor activity in TNBC xenograft models.

Fórmula: C₂₁H₂₃NO₄

Cor e Forma: Solid

Peso molecular: 353.41

Ref: TM-T200468