CAS 28608-75-5

Orientina

Descrição:

Orientina, com o número CAS 28608-75-5, é um glicosídeo flavonoide encontrado principalmente em várias plantas, particularmente nas folhas de certas espécies como o trigo sarraceno comum e em algumas ervas. É caracterizado por sua cor amarelada e é conhecido por suas propriedades antioxidantes, que contribuem para seus potenciais benefícios à saúde. Orientina é solúvel em água e apresenta um sabor doce devido à sua estrutura glicosídica. Este composto é frequentemente estudado por seus efeitos farmacológicos, incluindo atividades anti-inflamatórias, anti-diabéticas e neuroprotetoras. Além disso, Orientina pode desempenhar um papel na proteção das células contra o estresse oxidativo e tem sido investigado por seu potencial em promover a saúde cardiovascular. Sua presença em fontes dietéticas sugere que pode contribuir para os benefícios gerais à saúde associados a uma dieta rica em plantas. Assim como muitos flavonoides, a biodisponibilidade e eficácia de Orientina podem ser influenciadas por vários fatores, incluindo o método de extração e a presença de outros compostos no material de origem.

Fórmula: C₂₁H₂₀O₁₁

InChI: InChI=1S/C21H20O11/c22-6-14-17(28)18(29)19(30)21(32-14)16-11(26)4-10(25)15-12(27)5-13(31-20(15)16)7-1-2-8(23)9(24)3-7/h1-5,14,17-19,21-26,28-30H,6H2/t14-,17-,18+,19-,21+/m1/s1

Chave InChI: InChIKey=PLAPMLGJVGLZOV-VPRICQMDSA-N

SMILES: OC=1C(=C2C(C(=O)C=C(O2)C3=CC(O)=C(O)C=C3)=C(O)C1)[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O

Sinónimos:

• (1S)-1,5-anhydro-1-[2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-chromen-8-yl]-D-glucitol
• 2-(3,4-Dihydroxyphenyl)-8-beta-D-glucopyranosyl-5,7-dihydroxy-4H-1-benzopyran-4-one
• 2-(3,4-Dihydroxyphenyl)-8-β-<span class="text-smallcaps">D</span>-glucopyranosyl-5,7-dihydroxy-4H-1-benzopyran-4-one
• 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-8-β-<span class="text-smallcaps">D</span>-glucopyranosyl-5,7-dihydroxy-
• 8-β-<span class="text-smallcaps">D</span>-Glucopyranosyl-3′,4′,5,7-tetrahydroxyflavone
• Luteolin 8-C-glucoside
• Luteolin 8-C-β-<span class="text-smallcaps">D</span>-glucopyranoside
• Luteolin 8-C-β-glucopyranoside
• Luteolin-8-glucoside
• Lutexin
• Orientin (flavone)
• Luteolin 8-C-β-D-glucopyranoside
• 2-(3,4-Dihydroxyphenyl)-8-β-D-glucopyranosyl-5,7-dihydroxy-4H-1-benzopyran-4-one
• Orientin

Orientin

CAS: 28608-75-5

Fórmula: C₂₁H₂₀O₁₁

Pureza: >98.0%(HPLC)

Cor e Forma: White to Light yellow powder to crystal

Peso molecular: 448.38

Ref: 3B-O0503

2-(3,4-Dihydroxyphenyl)-5,7-Dihydroxy-8-((2S,3R,4R,5S,6R)-3,4,5-Trihydroxy-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-2-Yl)-4H-Chromen-4-One

CAS: 28608-75-5

2-(3,4-Dihydroxyphenyl)-5,7-Dihydroxy-8-((2S,3R,4R,5S,6R)-3,4,5-Trihydroxy-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-2-Yl)-4H-Chromen-4-One

Fórmula: C₂₁H₂₀O₁₁

Pureza: 99%

Peso molecular: 448.38

Ref: 54-OR1009712

Orientin

CAS: 28608-75-5

Orientin

Fórmula: C₂₁H₂₀O₁₁

Pureza: 99.5%

Cor e Forma: Solid

Peso molecular: 448.38

Ref: 54-BUP11077

Orientin

CAS: 28608-75-5

Fórmula: C₂₁H₂₀O₁₁

Peso molecular: 448.38

Ref: 4Z-O-107001

Orientin

CAS: 28608-75-5

Fórmula: C₂₁H₂₀O₁₁

Pureza: ≥ 97.0%

Cor e Forma: Yellow powder

Peso molecular: 448.38

Ref: 7W-GC4819

Orientin 100 µg/mL in Acetonitrile:Water

Produto Controlado

CAS: 28608-75-5

Fórmula: C₂₁H₂₀O₁₁

Cor e Forma: Single Solution

Peso molecular: 448.38

Ref: 04-A15743000WL-100

Orientin

CAS: 28608-75-5

Fórmula: C₂₁H₂₀O₁₁

Cor e Forma: Neat

Peso molecular: 448.38

Ref: 04-C15743000

4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-8-β-D-glucopyranosyl-5,7-dihydroxy-

CAS: 28608-75-5

Fórmula: C₂₁H₂₀O₁₁

Pureza: 60%

Cor e Forma: Solid

Peso molecular: 448.3769

Ref: IN-DA002VV3

Orientin (Standard)

CAS: 28608-75-5

Orientin (Standard) is a reference standard for research and analysis in studies involving Orientin. 1. Orientin (Luteolin-8-glucoside) may be regarded as a candidate therapeutic agent for treatment of vascular inflammatory diseases via inhibition of the HMGB1 signaling pathway. 2. Orientin protects vascular barrier integrity by inhibiting hyperpermeability, expression of CAMs, and adhesion and migration of leukocytes, thereby endorsing its usefulness as a therapy for vascular inflammatory diseases. 3. Orientin has neuroprotection effect by the intracellular mediation of caspase activity; may alleviate cognitive deficits and oxidative stress in AD mice; can exert antidepressant-like effects on CUMS mice, specifically by improving central oxidative stress, neurotransmission, and neuroplasticity.

Fórmula: C₂₁H₂₀O₁₁

Cor e Forma: Solid

Peso molecular: 448.3769

Ref: TM-TMSM-1796

Orientin

CAS: 28608-75-5

Orientin analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Fórmula: C₂₁H₂₀O₁₁

Pureza: (HPLC) ≥99%

Cor e Forma: Powder

Peso molecular: 448.38

Ref: 11-1054S

Orientin

CAS: 28608-75-5

Orientin has various activities including anti-oxidant, anti-aging, anti-viral, anti-bacterial, anti-inflammation, vasodilatation and cardioprotective, antiadipogenesis, antinociceptive, radiation protective, neuroprotective, and antidepressant-like effects. Orientin protects H9c2 cardio-mytocytes against I/R-induced apoptosis by modulating the mPTP opening, and this role of orientin may involve the PI3K/Akt signaling pathway; it also can decrease C/EBPα and PPARγ protein expression level in 3T3-L1 cells.

Fórmula: C₂₁H₂₀O₁₁

Pureza: 95%~99%

Peso molecular: 448.38

Ref: BP-BP1042

Orientin

Produto Controlado

CAS: 28608-75-5

Stability Hygroscopic
Applications Orientin is a flavone, a chemical flavonoid compound. Orientin have been investigated for its anti-oxidant, antihypertensive and antihyperlipidemic effects.
References Yao, H., et al.: Food Chem., 135, 2802 (2012); Gordon, A., et al.: Food Chem., 133, 256 (2012); Cermak, R., et al.: Expert. Opin. Drug. Metab. Toxicol., 4, 17 (2008);

Fórmula: C₂₁H₂₀O₁₁

Cor e Forma: Neat

Peso molecular: 448.38

Ref: TR-O674900

2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-8-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)-4H-chromen-4-one

CAS: 28608-75-5

2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-8-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)-4H-chromen-4-one

Fórmula: C₂₁H₂₀O₁₁

Pureza: 60% +(HPLC)

Peso molecular: 448.38

Ref: IN-DG01415500

Orientin

CAS: 28608-75-5

1.

Fórmula: C₂₁H₂₀O₁₁

Pureza: 98.77% - 99.96%

Cor e Forma: Yellow Powder

Peso molecular: 448.3769

Ref: TM-T6S0721

Orientin

CAS: 28608-75-5

Natural glycoside

Fórmula: C₂₁H₂₀O₁₁

Pureza: ≥ 98.0 % (HPLC)

Cor e Forma: Powder

Peso molecular: 448.38

Ref: 5G-89746

Orientin

CAS: 28608-75-5

Orientin (Luteolin-8-C-glucoside) is a flavonoid that has been shown to have biological properties, such as anti-inflammatory and antioxidant activities, which may be due to its ability to inhibit toll-like receptor 4. Orientin is an effective inhibitor of the growth of Leishmania amazonensis in vitro. It also inhibits the growth of Candida glabrata, a fungus that causes oral thrush and other infections. Orientin has been shown to have high values in inflammatory bowel diseases (IBD).

Fórmula: C₂₁H₂₀O₁₁

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 448.38 g/mol

Ref: 3D-MO08113

Orientin

CAS: 28608-75-5

Fórmula: C₂₁H₂₀O₁₁

Peso molecular: 448.4

Ref: BE-RMT12150

Orientin

CAS: 28608-75-5

Fórmula: C₂₁H₂₀O₁₁

Peso molecular: 448.4

Ref: BE-RMCO060000

ORIENTIN

CAS: 28608-75-5

Pureza: 98.0%

Cor e Forma: Solid

Peso molecular: 448.3800049

Ref: 10-F859737

Orientin

CAS: 28608-75-5

Fórmula: C₂₁H₂₀O₁₁

Peso molecular: 448.38

Ref: ST-EA-CP-O53000