CAS 2885961-55-5

Fórmula: C36H34F2N6O3

InChI: InChI=1S/C36H34F2N6O3/c1-3-25-28(37)10-7-21-15-24(45)16-26(30(21)25)32-31(38)33-27(17-39-32)34(42-18-22-8-9-23(19-42)44(22)29(46)4-2)41-35(40-33)47-20-36-11-5-13-43(36)14-6-12-36/h1,4,7,10,15-17,22-23,45H,2,5-6,8-9,11-14,18-20H2

Chave InChI: YUFVOCUAYXHCEL-UHFFFAOYSA-N

SMILES: C=CC(=O)N1C2CCC1CN(C2)C3=NC(=NC4=C(C(=NC=C43)C5=C6C(=CC(=C5)O)C=CC(=C6C#C)F)F)OCC78CCCN7CCC8

pan-KRAS-IN-4

CAS: 2885961-55-5

Pan-KRAS-IN-4 (compound 5) is a potent KRAS inhibitor, demonstrating IC50 values of 0.37 nM for Kras G12C and 0.19 nM for Kras G12V [1].

Fórmula: C₃₆H₃₄F₂N₆O₃

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 636.69

Ref: TM-T79799