CAS 2904690-41-9

Fórmula: C29H31F3N8O

InChI: InChI=1S/C29H31F3N8O/c1-37-12-14-38(15-13-37)18-20-5-6-22(16-23(20)29(30,31)32)35-28(41)21-9-11-39(19-21)27-8-7-26-34-17-25(40(26)36-27)24-4-2-3-10-33-24/h2-8,10,16-17,21H,9,11-15,18-19H2,1H3,(H,35,41)/t21-/m1/s1

Chave InChI: WYCSRUVPJUYDGP-OAQYLSRUSA-N

SMILES: CN1CCN(CC1)CC2=C(C=C(C=C2)NC(=O)[C@@H]3CCN(C3)C4=NN5C(=NC=C5C6=CC=CC=N6)C=C4)C(F)(F)F

TRK II-IN-1

CAS: 2904690-41-9

TRK II-IN-1: potent type II TRK inhibitor; IC50s: TRKA (3.3 nM), TRKB (6.4 nM), TRKC (4.3 nM), TRKA G667C (9.4 nM); also targets FLT3, RET, VEGFR2.

Fórmula: C₂₉H₃₁F₃N₈O

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 564.6

Ref: TM-T73033