CAS 2925211-47-6

Fórmula: C42H48Cl2N6O6

InChI: InChI=1S/C42H48Cl2N6O6/c43-32-27-37(56-36-19-22-45-28-31(36)42(55)49-25-24-48(30-14-15-30)34-10-5-6-11-35(34)49)33(44)26-29(32)13-16-39(52)47-21-8-2-1-7-20-46-38(51)12-4-3-9-23-50-40(53)17-18-41(50)54/h5-6,10-11,17-19,22,26-28,30H,1-4,7-9,12-16,20-21,23-25H2,(H,46,51)(H,47,52)

Chave InChI: JFKZRMIIIBJHLC-UHFFFAOYSA-N

SMILES: C1CC1N2CCN(C3=CC=CC=C32)C(=O)C4=C(C=CN=C4)OC5=C(C=C(C(=C5)Cl)CCC(=O)NCCCCCCNC(=O)CCCCCN6C(=O)C=CC6=O)Cl

TGR5 agonist 6

CAS: 2925211-47-6

Compound 22b, also known as TGR5 agonist 6, is a non-systemic, intestine-targeted TGR5 agonist that demonstrates significant and sustained blood glucose-lowering effects with an acceptable safety profile.

Fórmula: C₄₂H₄₈Cl₂N₆O₆

Cor e Forma: Solid

Peso molecular: 803.77

Ref: TM-T200705