CAS 29883-15-6

Amigdalina

Descrição:

Amigdalina é um composto que ocorre naturalmente classificado como um glicosídeo cianogênico, encontrado principalmente nas sementes de frutas como damascos, amêndoas e cerejas. Sua fórmula química é C14H17NO6, e é conhecido por seu potencial de liberar cianeto quando metabolizado. Amigdalina aparece como um pó cristalino branco e é solúvel em água e álcool. Foi estudado por seus supostos benefícios à saúde, particularmente na medicina alternativa, embora as evidências científicas que apoiam sua eficácia sejam limitadas e controversas. O composto pode ser tóxico em altas doses devido à liberação de cianeto, o que pode levar a sérios riscos à saúde. Como resultado, o consumo de sementes ricas em Amigdalina deve ser abordado com cautela. Agências reguladoras levantaram preocupações sobre sua segurança, e não é aprovado como tratamento para qualquer condição médica. No geral, embora Amigdalina tenha despertado interesse por seu uso histórico e potenciais propriedades terapêuticas, seu perfil de segurança exige consideração cuidadosa.

Fórmula: C₂₀H₂₇NO₁₁

InChI: InChI=1/C20H27NO11/c21-6-10(9-4-2-1-3-5-9)30-20-18(28)16(26)14(24)12(32-20)8-29-19-17(27)15(25)13(23)11(7-22)31-19/h1-5,10-20,22-28H,7-8H2/t10-,11+,12+,13+,14+,15-,16-,17+,18+,19+,20+/m0/s1

Chave InChI: InChIKey=XUCIJNAGGSZNQT-JHSLDZJXSA-N

SMILES: O([C@@H](C#N)C1=CC=CC=C1)[C@@H]2O[C@H](CO[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)[C@@H](O)[C@H](O)[C@H]2O

Sinónimos:

• (2R)-[(6-O-hexopyranosylhexopyranosyl)oxy](phenyl)ethanenitrile
• (2R)-{[6-O-(beta-D-glucopyranosyl)-beta-D-glucopyranosyl]oxy}(phenyl)ethanenitrile
• (R)-Amygdalin
• (αR)-α-[(6-O-β-<span class="text-smallcaps">D</smallcap>-Glucopyranosyl-β-<smallcap>D</span>-glucopyranosyl)oxy]benzeneacetonitrile
• <span class="text-smallcaps">D</span>-Amygdalin
• Amygdalin
• Amygdaloside
• Amygdaloside (disaccharide)
• Apricot Kernel Extract
• Benzeneacetonitrile, α-[(6-O-β-<span class="text-smallcaps">D</smallcap>-glucopyranosyl-β-<smallcap>D</span>-glucopyranosyl)oxy]-, (R)-
• Benzeneacetonitrile, α-[(6-O-β-<span class="text-smallcaps">D</smallcap>-glucopyranosyl-β-<smallcap>D</span>-glucopyranosyl)oxy]-, (αR)-
• D-Amygdalin (1.12428)
• Mandelonitrile-β-gentiobioside
• NSC 15780
• {[6-O-(beta-D-glucopyranosyl)-beta-D-glucopyranosyl]oxy}(phenyl)acetonitrile
• Benzeneacetonitrile, α-[(6-O-β-D-glucopyranosyl-β-D-glucopyranosyl)oxy]-, (αR)-
• D-Amygdalin
• (αR)-α-[(6-O-β-D-Glucopyranosyl-β-D-glucopyranosyl)oxy]benzeneacetonitrile
• Benzeneacetonitrile, α-[(6-O-β-D-glucopyranosyl-β-D-glucopyranosyl)oxy]-, (R)-
• D-Amygdalin hydrate
• benzeneacetonitrile,alpha-((6-o-beta-d-glucopyranosyl-beta-d-glucopyranosyl)
• LAETRILE
• benzeneacetonitrile,alpha-((6-o-beta-d-glucopyranosyl-beta-d-glucopyranosyl)ox
• (r)-alpha-((6-o-beta-d-glucopyranosyl-beta-d-glucopyranosyl)oxy)benzeneaceto
• (r)-oxy)
• BENZENEACETONITRILE-[(6-O-BETA-D-GLUCOPYRANOSYL-BETA-D-GLUCOPYRANOSYL)OXY]-, (R)-
• (r)-y)
• 6-O-BETA-D-GLUCOSIDO-BETA-D-GLUCOSIDE
• D-MANDELONITRILE 6-O-BETA-D-GLUCOSIDO-BETA-D-GLUCOSIDE D-MANDELONITRILE BETA-GENTIOBIOSIDE
• D-MANDELONITRILE-BETA-D-GLUCOSIDO-6-BETA-D-GLUCOSIDE
• D-MANDELONITRILE-BETA-GENTIOBIOSIDE
• GLUCOPRUNASIN
• MANDELONITRILE GENTIOBIOSIDE
• (r)-alpha-((6-o-beta-d-glucopyranosyl-beta-d-glucopyranosyl)oxy)benzeneacetonit

Amygdalin

CAS: 29883-15-6

Fórmula: C₂₀H₂₇NO₁₁

Pureza: >97.0%(HPLC)

Cor e Forma: White to Almost white powder to crystal

Peso molecular: 457.43

Ref: 3B-A0443

D-Amygdalin, 98%

CAS: 29883-15-6

A benzylic glycoside that has been used as an antineoplastic agent

Fórmula: C₂₀H₂₇NO₁₁

Pureza: 98%

Cor e Forma: Crystaline powder

Peso molecular: 457.43

Ref: 02-J61472

D-Amygdalin hydrate, 96%

CAS: 29883-15-6

A benzylic glycoside that has been used as an antineoplastic agent This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU refere

Fórmula: C₂₀H₂₇NO₁₁

Pureza: 96%

Cor e Forma: White, Crystals or powder or crystalline powder or fused solid

Peso molecular: 457.43

Ref: 02-L12731

AMYGDALIN CRS

CAS: 29883-15-6

AMYGDALIN CRS

Ref: 41-Y0002302

Amygdalin

CAS: 29883-15-6

Amygdalin

Fórmula: C₂₀H₂₇NO₁₁

Pureza: 98.5%

Peso molecular: 457.43

Ref: 54-BUP14761

Amygdalin

CAS: 29883-15-6

Amygdalin

Fórmula: C₂₀H₂₇NO₁₁

Pureza: >97%

Cor e Forma: Solid

Peso molecular: 457.43

Ref: 54-OR1030162

Amygdalin

CAS: 29883-15-6

Fórmula: C₂₀H₂₇NO₁₁

Pureza: (HPLC) ≥ 98.0%

Cor e Forma: White crystalline powder

Peso molecular: 457.44

Ref: 7W-GC5067

Amygdalin

CAS: 29883-15-6

Fórmula: C₂₀H₂₇NO₁₁

Pureza: 95%

Cor e Forma: Solid

Peso molecular: 457.4285

Ref: IN-DA00I5JE

Amygdalin

CAS: 29883-15-6

Amygdalin analytical standard provided with chromatographic purity, to be used as reference material for qualitative determination.

Fórmula: C₂₀H₂₇NO₁₁

Pureza: (HPLC) ≥90%

Cor e Forma: Powder

Peso molecular: 457.44

Ref: 11-7201A

Amygdalin (Standard)

CAS: 29883-15-6

Amygdalin (Standard) is a reference standard for research and analysis in studies involving Amygdalin. Amygdalin (Laetrile) has antifibrotic, antitumor, anti-inflammatory and analgesic effects, amygdalin joint HSYA could inhibit the degeneration of the endplate chondrocytes derived from intervertebral discs of rats induced by IL-1beta and better than the single use of Amygdalin or HSYA. Amygdalin induces apoptotic cell death in human DU145 and LNCaP prostate cancer cells by caspase-3 activation through down-regulation of Bcl-2 and up-regulation of Bax.

Fórmula: C₂₀H₂₇NO₁₁

Peso molecular: 457.43

Ref: TM-TMSM-2341

D-Amygdalin

CAS: 29883-15-6

Fórmula: C₂₀H₂₇NO₁₁

Cor e Forma: Neat

Peso molecular: 457.43

Ref: 04-C10245500

Amygdalin

CAS: 29883-15-6

Amygdalin induces apoptotic cell death in human DU145 and LNCaP prostate cancer cells by caspase-3 activation through down-regulation of Bcl-2 and up-regulation of Bax,suggests it may offer a valuable option for the treatment of prostate cancers.

Fórmula: C₂₀H₂₇NO₁₁

Pureza: 95%~99%

Cor e Forma: Powder

Peso molecular: 457.432

Ref: BP-BP0162

(R)-Amygdalin

CAS: 29883-15-6

Stability Hygroscopic
Applications (R)-Amygdalin is used in the treatment of psoriasis, an immune-mediated illness. Also it has been shown to induce apoptosis in human cervical cancer cells.
References Perez, J. et al.: Future Med. Chem., 5, 799 {2013); Chen, Y. et al.: Immunopharm. Immunotoxicol., 35, 43 (2013);

Fórmula: C₂₀H₂₇NO₁₁

Cor e Forma: Neat

Peso molecular: 457.43

Ref: TR-A576840

Amygdalin

CAS: 29883-15-6

(R)-2-Phenyl-2-(((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-((((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)methyl)tetrahydro-2H-pyran-2-yl)oxy)acetonitrile

Fórmula: C₂₀H₂₇NO₁₁

Pureza: 95%

Peso molecular: 457.43

Ref: IN-DG33111

Amygdalin

CAS: 29883-15-6

Amygdalin (Laetrile) offers antitumor, anti-inflammatory, analgesic properties; enhances chondrocyte health; triggers prostate cancer cell apoptosis.

Fórmula: C₂₀H₂₇NO₁₁

Pureza: 98.89%

Cor e Forma: Solid

Peso molecular: 457.43

Ref: TM-T2795

Amygdalin

CAS: 29883-15-6

Natural glycoside

Fórmula: C₂₀H₂₇NO₁₁

Pureza: ≥ 95.0 % (HPLC)

Cor e Forma: Powder

Peso molecular: 457.44

Ref: 5G-89559

D-Amygdalin

CAS: 29883-15-6

Cyanogenic glycoside that is a component of bitter almonds and apricot pits. Used to differentiate bacteria on the basis of carbohydrate fermentation abilities.

Fórmula: C₂₀H₂₇NO₁₁

Pureza: Min. 98 Area-%

Cor e Forma: White Powder

Peso molecular: 457.43 g/mol

Ref: 3D-OM05087

Amygdalin

CAS: 29883-15-6

Fórmula: C₂₀H₂₇NO₁₁

Peso molecular: 457.4

Ref: BE-RMT12870

D-Amygdalin

CAS: 29883-15-6

Fórmula: C₂₀H₂₇NO₁₁

Peso molecular: 457.4

Ref: BE-BePure-20343

D-Amygdalin extrapure, 97%

CAS: 29883-15-6

Fórmula: C₂₀H₂₇NO₁₁

Pureza: min. 97%

Cor e Forma: White to off-white, Crystalline powder

Peso molecular: 457.44

Ref: SR-85441