CAS 3007658-94-5

Fórmula: C24H23N5O2

InChI: InChI=1S/C24H23N5O2/c1-15-13-19-17(23(30)31)9-5-11-20(19)29(15)24-27-21-18(10-6-12-25-21)22(28-24)26-14-16-7-3-2-4-8-16/h2-5,7-9,11,13H,6,10,12,14H2,1H3,(H,30,31)(H2,25,26,27,28)

Chave InChI: PNYJJAVZMANKFI-UHFFFAOYSA-N

SMILES: CC1=CC2=C(C=CC=C2N1C3=NC4=C(CCCN4)C(=N3)NCC5=CC=CC=C5)C(=O)O

VCP/p97 IN-2

CAS: 3007658-94-5

VCP/p97 IN-2 (Compound V13) is a VCP/p97 inhibitor with an IC50 of 32 nM for p97. It exhibits excellent antitumor activity, significantly suppressing tumor growth in a Molm-13 xenograft mouse model. VCP/p97 IN-2 is applicable for research in acute myeloid leukemia (AML).

Fórmula: C₂₄H₂₃N₅O₂

Cor e Forma: Solid

Peso molecular: 413.47

Ref: TM-T210967