CAS 3011029-58-3

XL01126

Fórmula: C₅₀H₆₄ClFN₁₀O₆S₂

InChI: InChI=1S/C50H64ClFN10O6S2/c1-30-41(69-29-56-30)34-12-10-31(11-13-34)24-54-44(64)39-23-36(63)27-62(39)46(66)42(58-47(67)50(52)16-17-50)49(2,3)70-28-33-8-6-32(7-9-33)26-60-18-20-61(21-19-60)45(65)35-14-15-38(40(22-35)68-5)57-48-55-25-37(51)43(53-4)59-48/h10-15,22,25,29,32-33,36,39,42,63H,6-9,16-21,23-24,26-28H2,1-5H3,(H,54,64)(H,58,67)(H2,53,55,57,59)/t32?,33?,36-,39+,42-/m1/s1

Chave InChI: HKSBXNVKPFTBIG-WUEKOBJSSA-N

SMILES: CC1=C(SC=N1)C2=CC=C(C=C2)CNC(=O)[C@@H]3C[C@H](CN3C(=O)[C@H](C(C)(C)SCC4CCC(CC4)CN5CCN(CC5)C(=O)C6=CC(=C(C=C6)NC7=NC=C(C(=N7)NC)Cl)OC)NC(=O)C8(CC8)F)O

Sinónimos:

• XL01126

(2S,4R)-1-((R)-3-((((1R,4R)-4-((4-(4-((5-Chloro-4-(methylamino)pyrimidin-2-yl)amino)-3-methoxybenzoyl)piperazin-1-yl)methyl)cyclohexyl)methyl)thio)-2-(1-fluorocyclopropane-1-carboxamido)-3-methylbutan

CAS: 3011029-58-3

(2S,4R)-1-((R)-3-((((1R,4R)-4-((4-(4-((5-Chloro-4-(methylamino)pyrimidin-2-yl)amino)-3-methoxybenzoyl)piperazin-1-yl)methyl)cyclohexyl)methyl)thio)-2-(1-fluorocyclopropane-1-carboxamido)-3-methylbutan

Fórmula: C₅₀H₆₄ClFN₁₀O₆S₂

Pureza: 98%

Peso molecular: 1019.71

Ref: 54-PC1006489

XL01126

CAS: 3011029-58-3

XL01126 LRRK2 degrader (DC50 14 nM G2019S, 32 nM WT) BBB-penetrant probe for Parkinson’s disease and LRRK2 signaling and protein degradation studies.

Fórmula: C₅₀H₆₄ClFN₁₀O₆S₂

Pureza: 99.98%

Cor e Forma: Solid

Peso molecular: 1019.69

Ref: TM-T74638

(2S,4R)-1-((R)-3-((((1R,4R)-4-((4-(4-((5-Chloro-4-(Methylamino)Pyrimidin-2-Yl)Amino)-3-Methoxybenzoyl)Piperazin-1-Yl)Methyl)Cyclohexyl)Methyl)Thio)-2-(1-Fluorocyclopropane-1-Carboxamido)-3-Methylbutanoyl)-4-Hydroxy-N-(4-(4-Methylthiazol-5-Yl)Benzyl)Pyrrol

CAS: 3011029-58-3

Fórmula: C₅₀H₆₄ClFN₁₀O₆S₂

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 1019.6880

Ref: IN-DA02AOYR