CAS 302-79-4

Ácido retinoico

Descrição:

Ácido retinoico, com o número CAS 302-79-4, é um metabolito da vitamina A (retinol) e desempenha um papel crucial em vários processos biológicos, incluindo crescimento celular, diferenciação e desenvolvimento embrionário. Existe em duas formas principais: todo-trans-Ácido retinoico e 13-cis-Ácido retinoico, cada uma exibindo atividades biológicas distintas. Ácido retinoico é um composto lipofílico, o que significa que é solúvel em solventes orgânicos, mas tem solubilidade limitada em água. Atua principalmente através de receptores nucleares, influenciando a expressão gênica e as funções celulares. Este composto é essencial em dermatologia, particularmente no tratamento da acne e do envelhecimento da pele, pois promove a renovação celular e reduz a hiperqueratinização. Além disso, Ácido retinoico está envolvido na regulação das respostas imunológicas e tem aplicações terapêuticas potenciais no tratamento do câncer, particularmente na leucemia promielocítica aguda. No entanto, seu uso deve ser cuidadosamente monitorado devido a possíveis efeitos colaterais, incluindo teratogenicidade e irritação da pele. No geral, Ácido retinoico é um composto vital tanto em processos fisiológicos quanto em aplicações terapêuticas.

Fórmula: C₂₀H₂₈O₂

InChI: InChI=1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8+,16-14+

Chave InChI: InChIKey=SHGAZHPCJJPHSC-YCNIQYBTSA-N

SMILES: C(=C/C(=C/C=C/C(=C/C(O)=O)/C)/C)\C=1C(C)(C)CCCC1C

Sinónimos:

• (11Cis,13Cis)-7,8-Dihydroretinoic Acid
• (9Cis)-Retinoic Acid
• (all-E)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid
• (all-E)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexene-1-yl)-2,4,6,8-nonatetraenoic acid
• 15-Oxidoretinal
• 2,4,6,8-Nonatetraenoic acid, 3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-, (all-E)-
• 3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid
• Aberel
• Acide retinoique
• Agn 100335
• Airol
• Aknoten
• Atra
• Atragen
• Cordes Vas
• Dermairol
• Epi-Aberel
• Eudyna
• N,N'-hexane-1,6-diyldiacetamide
• Nsc 122578
• Nsc 122758
• Renova
• Retacnyl
• Retin A
• Retinoic Acid
• Retinoic acid, all-trans-
• Retionoic Acid
• Ro 1-5488
• Tretin M
• Tretin M, 3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-, (all-E)-
• Tretinion
• Tretinoin (Retionoic Acid)
• Tretinoine
• Tretinoino
• Vesanoid
• Vesnaroid
• Vitamin A acid
• Vitamin A acid, all-trans-
• Vitamin A1 acid, all-trans-
• Vitamin A₁ acid, all-trans-
• all-(E)-Retinoic acid
• all-trans-Retinoic acid
• all-trans-Tretinoin
• all-trans-Vitamin A acid
• all-trans-β-Retinoic acid
• trans-Retinoic acid
• β-Retinoic acid
• Tretinoein
• Tretinoin
• AKOS 92103
• 3,7-DIMETHYL-9-(2,6,6-TRIMETHYL-1-CYCLOHEXEN-1-YL)-2Z,4E,6E,8E-NONATETRANENOIC ACID
• ALL-TRANS-RETINOIE ACID
• ISOTRETINOIN
• 3,7-DIMETHYL-9-(2,6,6-TRIMETHYL-1-CYCLOHEXEN-1-YL)-2E,4E,6E,8E-NONATETRAENOIC ACID
• RETINOIC ACID ALL TRANS ISOMER
• 13-CIS-RETINOIC ACID
• 9-TRANS-TRETINOIN
• (L)-ISOTRETINOIN
• TRANS VITAMIN A ACID
• RETINOIC ACID, 13-CIS-

Retinoic Acid

CAS: 302-79-4

Fórmula: C₂₀H₂₈O₂

Pureza: >93.0%(HPLC)

Cor e Forma: Light yellow to Amber to Dark green powder to crystal

Peso molecular: 300.44

Ref: 3B-R0064

Retinoic acid, 97%

CAS: 302-79-4

Retinoic acid (tretinoin or all-trans-retinoic acid (ATRA)), 302-79-4, is a naturally occuring derivative of retinol which is implicated in cell differentiation. Learn more.

Fórmula: C₂₀H₂₈O₂

Pureza: 97%

Cor e Forma: Pale yellow to yellow, Powder or crystalline powder

Peso molecular: 300.44

Ref: 02-044540

TRETINOIN CRS

CAS: 302-79-4

TRETINOIN CRS

Fórmula: C₂₀H₂₈O₂

Cor e Forma: Added Modified

Peso molecular: 300.4351

Ref: 41-T1850000

Tretinoin

CAS: 302-79-4

Tretinoin

Fórmula: C₂₀H₂₈O₂

Pureza: 99.5%

Cor e Forma: Yellow

Peso molecular: 300.20893

Ref: 47-1205

Tretinoin

CAS: 302-79-4

Vitamins a and their derivatives unmixed

Fórmula: C₂₀H₂₈O₂

Cor e Forma: Yellow Powder

Peso molecular: 300.44

Ref: 45-1674004

Retinoic acid

CAS: 302-79-4

Retinoic acid (Tretinoin) binds to and activates RARs, thereby inducing changes in gene expression that lead to inhibition of tumorigenesis.

Fórmula: C₂₀H₂₈O₂

Pureza: 97.21% - 99.60%

Cor e Forma: Yellow-Orange Powder

Peso molecular: 300.44

Ref: TM-T1051

Tretinoin (all-trans-Retinoic Acid, Isotretinoin EP Impurity A)

CAS: 302-79-4

Fórmula: C₂₀H₂₈O₂

Peso molecular: 300.44

Ref: 4Z-T-114001

Retinoic acid

CAS: 302-79-4

Fórmula: C₂₀H₂₈O₂

Pureza: 98.0 - 102.0 % (dried basis)

Cor e Forma: Yellow powder

Peso molecular: 300.44

Ref: 7W-GP4026

Retinoic Acid

CAS: 302-79-4

Retinoic Acid

Fórmula: C₂₀H₂₈O₂

Pureza: 99%

Cor e Forma: Solid-Powder

Peso molecular: 300.44

Ref: 54-OR1014889

Tretinoin-d5 (all-trans-Retinoic Acid-d5, Isotretinoin EP Impurity A-d5)

CAS: 302-79-4, 78996-15-3

Fórmula: C₂₀H₂₃D₅O₂

Cor e Forma: Pale Yellow Solid

Peso molecular: 305.47

Ref: 4Z-T-114002

Retinoic acid, USP grade

CAS: 302-79-4

Fórmula: C₂₀H₂₈O₂

Pureza: (Titration) 97.0 - 103.0 % (dried basis)

Cor e Forma: Yellow to light-orange crystalline powder

Peso molecular: 300.44

Ref: 7W-GP2891

Retinoic acid

CAS: 302-79-4

Retinoic acid

Fórmula: C₂₀H₂₈O₂

Pureza: ≥95%

Peso molecular: 300.44

Ref: 54-BUP14667

Tretinoin

Produto Controlado

CAS: 302-79-4

Fórmula: C₂₀H₂₈O₂

Cor e Forma: Neat

Peso molecular: 300.44

Ref: 04-C17608000

Tretinoin

Produto Controlado

CAS: 302-79-4

Fórmula: C₂₀H₂₈O₂

Cor e Forma: Neat

Peso molecular: 300.44

Ref: 86-MM1110.00

all-trans-Retinoic Acid

CAS: 302-79-4

Stability Light Sensitive
Applications Physiological metabolite of vitamin A. Effects gene expression via nuclear retinoic acid receptors (RAR); mediates cellular growth and differentiation.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Kamm, J.J., et al.: J. Am. Acad. Dermatol., 6, 652 (1982), Warrel, R.P., et al.: Leukemia, 8, 929 (1994), Sasai, Y., et al.: J. Neurol., 249, 41 (2002),

Fórmula: C₂₀H₂₈O₂

Cor e Forma: Neat

Peso molecular: 300.44

Ref: TR-R250200

all-trans-Retinoic acid

Produto Controlado

CAS: 302-79-4

Retinoic acid receptor (RAR) agonist; inhibits melanocyte activity

Fórmula: C₂₀H₂₈O₂

Pureza: Min. 95%

Cor e Forma: Yellow Powder

Peso molecular: 300.44 g/mol

Ref: 3D-FR17921

Tretinoin - Bio-X ™

Produto Controlado

CAS: 302-79-4

Tretinoin is a type of retinoic acid that can be used for the treatment of acne. It is a chemical inhibitor that binds to nuclear receptors and leads to an increase in apoptosis. This type of retinoic acid helps with cell detachment and increases shedding thus increasing cell turnover. Tretinoin has been shown to have antibacterial efficacy against Staphylococcus aureus, as well as synergistic effects when combined with other agents, such as cyclic lipopeptide antibiotics and quinolones. Additionally, Tretinoin is used in the research and treatment for promyelocytic leukaemia.

Fórmula: C₂₀H₂₈O₂

Pureza: Min. 95%

Cor e Forma: Yellow Powder

Peso molecular: 300.44 g/mol

Ref: 3D-BR164493

Tretinoin

CAS: 302-79-4

Fórmula: C₂₀H₂₈O₂

Peso molecular: 300.44

Ref: ST-EA-CP-T101000

Retinoic acid, Isotretinoin Impurity

CAS: 302-79-4

Pureza: 97%

Peso molecular: 300.21

Ref: 10-F570782

(2E,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid

CAS: 302-79-4

Fórmula: C₂₀H₂₈O₂

Pureza: 98%

Cor e Forma: Solid, Yellow powder

Peso molecular: 300.442

Ref: 10-F317904