CAS 3031514-69-6

Fórmula: C45H54FN9O5

InChI: InChI=1S/C45H54FN9O5/c1-27-21-37(41(46)33-25-55(44(58)40(27)33)36-9-10-39(56)49-43(36)57)53-15-11-30(12-16-53)59-29-5-3-28(4-6-29)24-52-17-19-54(20-18-52)38-23-35(47-26-48-38)42-32-22-31(60-45(2)13-14-45)7-8-34(32)50-51-42/h7-8,21-23,26,28-30,36H,3-6,9-20,24-25H2,1-2H3,(H,50,51)(H,49,56,57)

Chave InChI: MMPCWXISESNYDH-UHFFFAOYSA-N

SMILES: CC1=CC(=C(C2=C1C(=O)N(C2)C3CCC(=O)NC3=O)F)N4CCC(CC4)OC5CCC(CC5)CN6CCN(CC6)C7=NC=NC(=C7)C8=NNC9=C8C=C(C=C9)OC1(CC1)C

PROTAC LRRK2 Degrader-1

CAS: 3031514-69-6

PROTAC LRRK2 Degrader-1 (compound 18) is a PROTAC degrader targeting leucine-rich repeat kinase 2 (LRRK2) with an IC50 of less than 10 nM. It is applicable for research in Parkinson's disease.

Fórmula: C₄₅H₅₄FN₉O₅

Peso molecular: 819.97

Ref: TM-T217746