CAS 3046378-98-4

Fórmula: C30H30F3N5O4

InChI: InChI=1S/C30H30F3N5O4/c1-40-20-7-4-18(5-8-20)35-29(39)22-15-21-23(30(31,32)33)16-28(37-25(21)17-26(22)41-2)36-24-9-6-19(14-27(24)42-3)38-12-10-34-11-13-38/h4-9,14-17,34H,10-13H2,1-3H3,(H,35,39)(H,36,37)

Chave InChI: LUUSQGGJIVYGID-UHFFFAOYSA-N

SMILES: COC1=CC=C(C=C1)NC(=O)C2=C(C=C3C(=C2)C(=CC(=N3)NC4=C(C=C(C=C4)N5CCNCC5)OC)C(F)(F)F)OC

SGK1-IN-6

CAS: 3046378-98-4

SGK1-IN-6 (compound 12f) is an SGK1 inhibitor with an IC50 value of 0.39 μM. In PC3 xenograft models using BALB/c nude mice, SGK1-IN-6 effectively hinders tumor growth without causing any observable toxicity.

Fórmula: C₃₀H₃₀F₃N₅O₄

Cor e Forma: Solid

Peso molecular: 581.586

Ref: TM-T205289