CAS 3056612-67-7

Fórmula: C42H44Cl2N8O6S

InChI: InChI=1S/C42H43ClN8O6S.ClH/c1-24-19-25(43)20-30(37(24)47-26-7-6-14-44-22-26)28-12-16-46-32-21-27(58-38(28)32)23-50-35(53)13-18-49(42(50)57)17-4-2-3-15-45-31-9-5-8-29-36(31)41(56)51(40(29)55)33-10-11-34(52)48-39(33)54;/h5,8-9,12-13,16,18-21,26,33,44-45,47H,2-4,6-7,10-11,14-15,17,22-23H2,1H3,(H,48,52,54);1H

Chave InChI: NSUMVMMLIUGUOY-UHFFFAOYSA-N

SMILES: CC1=CC(=CC(=C1NC2CCCNC2)C3=C4C(=NC=C3)C=C(S4)CN5C(=O)C=CN(C5=O)CCCCCNC6=CC=CC7=C6C(=O)N(C7=O)C8CCC(=O)NC8=O)Cl.Cl

PROTAC USP7 Degrader-2

CAS: 3056612-67-7

PROTACUSP7 Degrader-2 (Compound D16) is a potent and selective USP7 PROTAC degrader with a DC₅₀ of 1.91 μM (in TE-12 cells). It inhibits the migration of upper gastrointestinal (UGI) cancer cells while exhibiting weak antiproliferative activity. This compound is utilized for research on metastatic UGI cancer.

Fórmula: C₄₂H₄₄Cl₂N₈O₆S

Peso molecular: 859.82

Ref: TM-T215997