CAS 32607-79-7

Glycine, 23,2′3-trithiobis[L-γ-glutamyl-L-alanyl-

Descrição:

Bis-Glutathione Trisulfide is the organic salt.

Fórmula: C₂₀H₃₂N₆O₁₂S₃

InChI: InChI=1S/C20H32N6O12S3/c21-9(19(35)36)1-3-13(27)25-11(17(33)23-5-15(29)30)7-39-41-40-8-12(18(34)24-6-16(31)32)26-14(28)4-2-10(22)20(37)38/h9-12H,1-8,21-22H2,(H,23,33)(H,24,34)(H,25,27)(H,26,28)(H,29,30)(H,31,32)(H,35,36)(H,37,38)/t9-,10-,11-,12-/m0/s1

Chave InChI: FQEIPOORDCCMGQ-BJDJZHNGSA-N

SMILES: C(CC(=O)N[C@@H](CSSSC[C@@H](C(=O)NCC(=O)O)NC(=O)CC[C@@H](C(=O)O)N)C(=O)NCC(=O)O)[C@@H](C(=O)O)N

Sinónimos:

• GSSSG
• Glycine, 23,2′3-trithiobis[L-γ-glutamyl-L-alanyl-

Glutathione trisulfide

CAS: 32607-79-7

Glutathione trisulfide (GSSSG) is a potent neuroprotective agent with anti-inflammatory properties. It inhibits lipopolysaccharide (LPS)-induced inflammatory gene expression in retinal pigment epithelial cells through excessive activation of the ERK signaling pathway, independently of the NRF2/HMOX1 pathway. GSSSG is applicable in research on neurodegenerative diseases and ischemic spinal cord injury (SCI).

Fórmula: C₂₀H₃₂N₆O₁₂S₃

Peso molecular: 644.69

Ref: TM-T214776