CAS 328-50-7

Ácido 2-oxoglutárico

Descrição:

Ácido 2-oxoglutárico, também conhecido como alfa-cetoglutarato, é um intermediário chave no ciclo de Krebs, que é essencial para a respiração celular e a produção de energia em organismos aeróbicos. É um ácido dicarboxílico com a fórmula molecular C5H6O5 e apresenta dois grupos carboxila (-COOH) e um grupo cetona (C=O). Este composto é tipicamente encontrado em sua forma aniônica, conhecida como alfa-cetoglutarato, a pH fisiológico. Desempenha um papel crucial no metabolismo de aminoácidos e na síntese de neurotransmissores. Além disso, Ácido 2-oxoglutárico está envolvido na regulação de processos celulares, incluindo a modulação da expressão gênica e a manutenção do equilíbrio redox celular. Também é estudado por suas potenciais aplicações terapêuticas, incluindo seu papel como suplemento dietético para melhorar o desempenho atlético e sua participação em vários distúrbios metabólicos. O composto é geralmente reconhecido como seguro quando usado adequadamente, mas seus efeitos podem variar com base na dosagem e nas condições de saúde individuais.

Fórmula: C₅H₆O₅

InChI: InChI=1S/C5H6O5/c6-3(5(9)10)1-2-4(7)8/h1-2H2,(H,7,8)(H,9,10)

Chave InChI: InChIKey=KPGXRSRHYNQIFN-UHFFFAOYSA-N

SMILES: C(CCC(O)=O)(C(O)=O)=O

Sinónimos:

• 2-Ketoglutaric acid
• 2-Oxo-1,5-pentanedioic acid
• 2-Oxoglutaric Acid
• 2-Oxoglutarsaure
• 2-Oxopentanedioic acid
• Acide 2-oxoglutarique
• Acido 2-Oxoglutarico
• Glutaric acid, 2-oxo-
• Nsc 17391
• α-Ketoglutaric acid
• α-Oxoglutaric acid
• α-Oxopentanedioic acid
• α-keto-Glutaric acid
• 2-oxo-pentanedioicaci
• alpha-Ketoglutaric Acid
• 2-Oxpentanedioicacid
• 2-oxopentanedioate
• 2-KETOGLUTARIC ACID, DISODIUM SALT, DIHYDRATE BIOTECh GRADE 99.5%
• diammonium 2-oxopentanedioate
• 2-KETOGLUTARIC ACID 99+%
• Oxoglutaric acid
• KETO-GLU
• GAMMA-KETOGLUTARIC ACID
• -Ketoglutaricacid
• α-Ketoglutaricacid
• A-KETOGLUTARIC ACID FREE ACID CELL*CULTU RE TESTED
• 2-OXOPENTANDIOICACID
• Glutaric acid, alpha keto
• KetoglutaricAcid,FreeAcid
• N-oxoglutamic acid
• 2-KETOGLUTARIC ACID BIOSYNTH
• alpha-keto-Glutaric acid
• Pentanedioic acid, 2-oxo-
• A-KetoglutaricAcidPuriss
• FEMA 3891
• 2-Oxo-1,5-dipentanedioic acid
• PENTANEDIOIC ACID, 2-OXO-

2-Oxoglutaric Acid

CAS: 328-50-7

Fórmula: C₅H₆O₅

Pureza: >99.0%(T)

Cor e Forma: White to Light yellow powder to crystal

Peso molecular: 146.10

Ref: 3B-K0005

2-Ketoglutaric acid, 98%

CAS: 328-50-7

2-Ketoglutaric acid is used as an intermediate in the kreb’s cycle catalyzed by glutamate dehydrogenase enzyme on glutamate. It is also used in dietary supplements to improve protein synthesis. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. So

Fórmula: C₅H₆O₅

Pureza: 98%

Cor e Forma: White to pale yellow, Crystals or powder or crystalline powder

Peso molecular: 146.10

Ref: 02-A10256

2-Oxopentanedioic acid

CAS: 328-50-7

2-Oxopentanedioic acid

Fórmula: C₅H₆O₅

Pureza: 95

Cor e Forma: White Solid

Peso molecular: 146.09814

Ref: 54-OR4662

2-Ketoglutaric Acid

CAS: 328-50-7

Fórmula: C₅H₆O₅

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 146.0981

Ref: IN-DA003HHY

2-Ketoglutaric acid

CAS: 328-50-7

2-Ketoglutaric acid

Fórmula: C₅H₆O₅

Pureza: ≥98%

Peso molecular: 146.1

Ref: 54-BUP19492

2-Ketoglutaric acid

CAS: 328-50-7

Fórmula: C₅H₆O₅

Pureza: (Titration) 98.0 - 101.5 %

Cor e Forma: White to off-white crystalline powder

Peso molecular: 146.10

Ref: 7W-GP9006

2-Oxo-1,5-pentanedioic Acid-d6

CAS: 1173021-86-7, 328-50-7

Pureza: 98 atom % D

Peso molecular: 152.14

Ref: 3U-D8105

alfa-Ketoglutaric Acid

CAS: 328-50-7

Fórmula: C₅H₆O₅

Peso molecular: 146.10

Ref: 4Z-K-040001

2-Ketoglutaric acid

CAS: 328-50-7

2-Ketoglutaric acid is a reversible inhibitor of tyrosinase (IC50=15 mM). 2-Ketoglutaric acid is an intermediate of the Krebs cycle. High-Quality, Low-Cost!

Fórmula: C₅H₆O₅

Pureza: 99.28% - 99.92%

Cor e Forma: White Solid

Peso molecular: 146.10

Ref: TM-T5980

2-Oxopentanedioic acid

CAS: 328-50-7

Fórmula: C₅H₆O₅

Pureza: 95%

Cor e Forma: Powder or Crystalline Powder

Peso molecular: 146.098

Ref: 10-F069250

2-Ketoglutaric Acid

CAS: 328-50-7

Applications 2-Ketoglutaric Acid is a derivative of glutaric acid and is an intermediate in the kreb’s cycle catalyzed by glutamate dehydrogenase enzyme on glutamate.
References Son, J.Y., et al.: Nature., 496, 7443 (2013); Quartarao, C.E., et al.: Biochem., 52, 1765 (2013); Yum, S.H., et al.: Euro.J. Pharmacol., 699, 124 (2013);

Fórmula: C₅H₆O₅

Cor e Forma: Neat

Peso molecular: 146.1

Ref: TR-K191200

2-Ketoglutaric acid

CAS: 328-50-7

Used to differentiate microorganisms based on their metabolic properties.

Fórmula: C₅H₆O₅

Peso molecular: 146.10 g/mol

Ref: 3D-K-2400

a-Ketoglutaric acid

CAS: 328-50-7

a-Ketoglutaric acid is a naturally occurring organic compound that is found in the body as well as in plants. It belongs to the group of organic acids and is produced from the breakdown of amino acids, such as leucine and valine. a-Ketoglutaric acid has been shown to have physiological effects on cells and tissues by inhibiting enzymes involved in energy metabolism. In vitro assays have shown that a-ketoglutaric acid has inhibitory properties against plant metabolism. This drug also inhibits the transcriptional regulation of genes for fatty acid synthesis in human erythrocytes. A-ketoglutaric acid has also been shown to inhibit glucose production in rat liver cells, which may be due to its ability to bind covalently with proteins or lipids, changing their structures and functions.

Fórmula: C₅H₆O₅

Cor e Forma: White Off-White Powder

Peso molecular: 146.1 g/mol

Ref: 3D-FK09820

2-Ketoglutaric acid

CAS: 328-50-7

2-Oxopentanedioic acid

Fórmula: C₅H₆O₅

Pureza: 98% HPLC-ELSD

Peso molecular: 146.1

Ref: IN-DG01400429

2-Ketoglutaric acid

CAS: 328-50-7

2-Oxopentanedioic acid

Fórmula: C₅H₆O₅

Pureza: 95%

Peso molecular: 146.1

Ref: IN-DG20243

2-Ketoglutaric acid (Standard)

CAS: 328-50-7

2-Ketoglutaric acid (Standard) is a reference standard for research and analysis in studies involving 2-Ketoglutaric acid. 2-Ketoglutaric acid is a reversible inhibitor of tyrosinase (IC50=15 mM). 2-Ketoglutaric acid is an intermediate of the Krebs cycle and can produce either ATP or GTP. 2-Ketoglutaric acid also acts as a major carbon backbone for the nitrogen assimilation reaction.

Fórmula: C₅H₆O₅

Cor e Forma: Solid

Peso molecular: 146.10

Ref: TM-TMSM-3358

a-Ketoglutaric Acid extrapure, 99%

CAS: 328-50-7

Fórmula: C₅H₆O₅

Pureza: min. 99%

Cor e Forma: White to pale yellow, Crystalline powder, Clear, Colourless to pale yellow

Peso molecular: 146.10

Ref: SR-93929

a-Ketoglutaric Acid (High Purity) extrapure AR, 99.5%

CAS: 328-50-7

Fórmula: C₅H₆O₅

Pureza: min. 99.5%

Cor e Forma: White to pale yellow, Crystalline powder, Clear, Colourless to pale yellow

Peso molecular: 146.10

Ref: SR-28386