CAS 32981-85-4

(2R,3S)-N-benzoil-3-fenilisoserina éster metílico

Descrição:

(2R,3S)-N-benzoil-3-fenilisoserina éster metílico é um composto químico caracterizado por sua estereoquímica específica e grupos funcionais. Apresenta um grupo benzóico, que é um grupo carbonila ligado a um anel fenil, indicando seu potencial para interações típicas de compostos aromáticos. A presença da parte isoserina sugere que possui grupos funcionais amino e hidroxila, contribuindo para sua potencial solubilidade em solventes polares. A funcionalidade de éster metílico indica que o grupo ácido carboxílico da isoserina está esterificado, o que pode aumentar a lipofilicidade e influenciar sua reatividade. Este composto pode exibir atividade biológica devido à sua semelhança estrutural com aminoácidos, tornando-o de interesse na química farmacêutica. Sua estereoquímica, denotada pela configuração (2R,3S), é crucial para suas interações biológicas, uma vez que a disposição espacial dos átomos pode afetar significativamente as propriedades e o comportamento do composto em sistemas biológicos. No geral, a estrutura única deste composto o posiciona como uma molécula potencialmente valiosa em química medicinal e campos relacionados.

Fórmula: C₁₇H₁₇NO₄

InChI: InChI=1S/C17H17NO4/c1-22-17(21)15(19)14(12-8-4-2-5-9-12)18-16(20)13-10-6-3-7-11-13/h2-11,14-15,19H,1H3,(H,18,20)/t14-,15+/m0/s1

Chave InChI: InChIKey=UYJLJICUXJPKTB-LSDHHAIUSA-N

SMILES: [C@@H](NC(=O)C1=CC=CC=C1)([C@H](C(OC)=O)O)C2=CC=CC=C2

Sinónimos:

• (2R,3S)-1-benzoyl-2-hydroxy-3-aminophenylpionic acid ester
• (2R,3S)-Methyl 3-benzoylamino-2-hydroxy-3-phenylpropanoate
• (2R,3S)-N-Benzoyl-3-phenylisoserine methyl ester
• Benzenepropanoic acid, β-(benzoylamino)-α-hydroxy-, methyl ester, (αR,βS)-
• Benzenepropanoic acid, β-(benzoylamino)-α-hydroxy-, methyl ester, [R-(R*,S*)]-
• Isoserine, N-benzoyl-3-phenyl-, methyl ester, (2R,3S)-
• Lkt-T 0104
• Methyl (-)-(2R,3S)-3-benzoylamino-2-hydroxy-3-phenylpropionate
• Methyl(2R,3S)-3-(benzoylamino)-2-hydroxy-3-phenylpropanoale
• Methyl(2R,3S)-N-benzoylphenylisoserinate
• Methyl-(2R,3S)-N-Benzoyl-3-Phenylisos
• N-Benzoyl-3-Phenyl isoserine methyl ester
• Paclitaxel Side Chain No.4
• methyl (2R,3S)-3-(benzoylamino)-2-hydroxy-3-phenylpropanoate
• methyl (2R,3S)-3-benzamido-2-hydro-3-phenylpropionate

Methyl (2R,3S)-3-benzamido-2-hydroxy-3-phenylpropionate, 98%

CAS: 32981-85-4

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Fórmula: C₁₇H₁₇NO₄

Pureza: 98%

Peso molecular: 299.33

Ref: 02-H61641

Bz-RS-iSer(3-Ph)-OMe

CAS: 32981-85-4

Fórmula: C₁₇H₁₇NO₄

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 299.3212

Ref: IN-DA00I6BS

(2R,3S)-N-Benzoyl-3-phenylisoserine methyl ester

CAS: 32981-85-4

(2R,3S)-N-Benzoyl-3-phenylisoserine methyl ester

Fórmula: C₁₇H₁₇NO₄

Pureza: 98%

Peso molecular: 299.32118

Ref: 54-OR315016

Methyl (2R,3S)-3-(benzoylamino)-2-hydroxy-3-phenylpropanoate

CAS: 32981-85-4

Fórmula: C₁₇H₁₇NO₄

Peso molecular: 299.33

Ref: 7W-GY0500

Bz-RS-ISer(3-Ph)-Ome

CAS: 32981-85-4

Bz-RS-ISer(3-Ph)-Ome

Fórmula: C₁₇H₁₇NO₄

Pureza: ≥98%

Peso molecular: 299.32

Ref: 54-BUP17991

Methyl (2R,3S)-3-Benzamido-2-hydroxy-3-phenylpropanoate

Produto Controlado

CAS: 32981-85-4

Fórmula: C₁₇H₁₇NO₄

Cor e Forma: Neat

Peso molecular: 299.32

Ref: 86-MM1489.09

Methyl (2R,3S)-3-(benzoylamino)-2-hydroxy-3-phenylpropanoate

CAS: 32981-85-4

Fórmula: C₁₇H₁₇NO₄

Pureza: 95%~99%

Peso molecular: 299.326

Ref: BP-BP4346

Bz-RS-iSer(3-Ph)-OMe

CAS: 32981-85-4

Methyl (2R,3S)-3-benzamido-2-hydroxy-3-phenylpropanoate

Fórmula: C₁₇H₁₇NO₄

Pureza: 98%

Peso molecular: 299.32

Ref: IN-DG33236

Paclitaxel Impurity 11

CAS: 32981-85-4

Fórmula: C₁₇H₁₇NO₄

Peso molecular: 299.33

Ref: 4Z-P-2850

Bz-RS-ISer(3-Ph)-Ome

CAS: 32981-85-4

Bz-RS-ISer(3-Ph)-Ome (Methyl (2R,3S)-3-(benzoylamino)-2-hydroxy-3-phenylpropanoate) is a paclitaxel derivative that inhibits the HSV replication cycle.

Fórmula: C₁₇H₁₇NO₄

Pureza: 99.36% - 99.89%

Cor e Forma: White Solid

Peso molecular: 299.32

Ref: TM-T7055

(2R,3S)-N-Benzoyl-3-phenyl Isoserine Methyl Ester

Produto Controlado

CAS: 32981-85-4

Applications (2R,3S)-N-Benzoyl-3-phenyl Isoserine Methyl Ester is an intermediate in the preparation of potent anticancer drug Paclitaxel (P132500) used to study the location of the binding sites.
References Paal, K. et al.: Bioorg. Med. Chem., 15, 1323 (2007); Krawczyk, E. et al.: J. Pharm. Pharmacol., 57, 791 (2005);

Fórmula: C₁₇H₁₇NO₄

Cor e Forma: Neat

Peso molecular: 299.32

Ref: TR-B208560

(2R,3S)-Methyl 3-benzamido-2-hydroxy-3-phenylpropanoate

CAS: 32981-85-4

Fórmula: C₁₇H₁₇NO₄

Pureza: ≥98%

Peso molecular: 299.326

Ref: 10-F213091

Paclitaxel Impurity 54

CAS: 32981-85-4

Fórmula: C₁₇H₁₇NO₄

Peso molecular: 299.33

Ref: ST-EA-CP-P36033

Methyl (2R,3S)-N-benzoyl-3-phenylisoserine

CAS: 32981-85-4

Methyl (2R,3S)-N-benzoyl-3-phenylisoserine is a potent anticancer drug that inhibits the growth of tumor cells. It has been shown to be effective against breast cancer and prostate cancer cell lines and is currently being tested in clinical trials for its antitumor activity. Methyl (2R,3S)-N-benzoyl-3-phenylisoserine has been shown to induce apoptosis in a number of tumor cell lines and may function by increasing the intracellular level of reactive oxygen species. This drug also binds to microtubules, which are essential for the mitotic spindle assembly checkpoint that prevents cells from entering mitosis until all chromosomes are properly aligned at the metaphase plate.
Methyl (2R,3S)-N-benzoyl-3-phenylisoserine belongs to the group of taxane drugs and was first isolated from Taxus brevif

Fórmula: C₁₇H₁₇NO₄

Pureza: Min. 95%

Cor e Forma: White/Off-White Solid

Peso molecular: 299.32 g/mol

Ref: 3D-FM32203