CAS 332950-12-6

Fórmula: C23H21N3O3S2

InChI: InChI=1S/C23H21N3O3S2/c1-4-29-23(28)17-15(14-8-6-5-7-9-14)11-30-21(17)26-20(27)19-18(24)16-12(2)10-13(3)25-22(16)31-19/h5-11H,4,24H2,1-3H3,(H,26,27)

Chave InChI: BPVWCTZLAKMQDH-UHFFFAOYSA-N

SMILES: CCOC(=O)C1=C(SC=C1C2=CC=CC=C2)NC(=O)C3=C(C4=C(S3)N=C(C=C4C)C)N

ISR activator 3

CAS: 332950-12-6

ISR activator 3 (Compound cc81) is the active metabolite of A8. It activates the integrated stress response (ISR) by binding to RIG-I (KD≈ 0.55 μM) without inducing lipid droplet clearance. Additionally, ISR activator 3 enhances the interferon response under viral mimic signaling. This compound is applicable in studies of neurodegenerative diseases and immune stress.

Fórmula: C₂₃H₂₁N₃O₃S₂

Peso molecular: 451.56

Ref: TM-T214641