CAS 355140-49-7

Fórmula: C33H45N5O9

InChI: InChI=1S/C33H45N5O9/c1-5-7-10-23(36-32(45)26-12-9-15-38(26)33(46)24(11-8-6-2)34-20(4)39)30(43)37-25(18-28(40)41)31(44)35-21-13-14-22-19(3)16-29(42)47-27(22)17-21/h13-14,16-17,23-26H,5-12,15,18H2,1-4H3,(H,34,39)(H,35,44)(H,36,45)(H,37,43)(H,40,41)/t23-,24-,25-,26-/m0/s1

Chave InChI: WPTAROWBMZVECB-CQJMVLFOSA-N

SMILES: CCCC[C@@H](C(=O)N[C@@H](CC(=O)O)C(=O)NC1=CC2=C(C=C1)C(=CC(=O)O2)C)NC(=O)[C@@H]3CCCN3C(=O)[C@H](CCCC)NC(=O)C

Ac-Nle-Pro-Nle-Asp-AMC

CAS: 355140-49-7

Ac-nLPnLD-AMC, substrate for proteasome.

Fórmula: C₃₃H₄₅N₅O₉

Pureza: 97.34%

Cor e Forma: White Powder

Peso molecular: 655.75

Ref: 01-4030084

(S)-3-((S)-2-((S)-1-((S)-2-Acetamidohexanoyl)pyrrolidine-2-carboxamido)hexanamido)-4-((4-methyl-2-oxo-2H-chromen-7-yl)amino)-4-oxobutanoic acid

CAS: 355140-49-7

(S)-3-((S)-2-((S)-1-((S)-2-Acetamidohexanoyl)pyrrolidine-2-carboxamido)hexanamido)-4-((4-methyl-2-oxo-2H-chromen-7-yl)amino)-4-oxobutanoic acid

Fórmula: C₃₃H₄₅N₅O₉

Pureza: 98%

Peso molecular: 655.75

Ref: 54-OR1062989

Ac-Nle-Pro-Nle-Asp-AMC

CAS: 355140-49-7

Ac-Nle-Pro-Nle-Asp-AMC: 26S proteasome substrate for caspase-like activity analysis.

Fórmula: C₃₃H₄₅N₅O₉

Peso molecular: 655.7385

Ref: TM-T76038

Ac-Nle-Pro-Nle-Asp-AMC

CAS: 355140-49-7

Fórmula: C₃₃H₄₅N₅O₉

Pureza: 99.85%

Peso molecular: 655.7385

Ref: IN-DA00BXJE

Ac-Nle-Pro-Nle-Asp-AMC

CAS: 355140-49-7

Ac-Nle-Pro-Nle-Asp-AMC is a reactive molecule that has been shown to be neuroprotective and to inhibit insulin resistance in mammalian cells. Ac-Nle-Pro-Nle-Asp-AMC is able to stop neuronal death by binding to the proteolytic enzymes, such as ubiquitin ligases, and inhibiting their activity. This drug also inhibits the activity of c2c12 myotubes, which are muscle cells that have been used in research studies. Ac-Nle-Pro-Nle-Asp AMC binds to ubiquitin and prevents it from being degraded by the proteasome system, which is a cellular protein degradation pathway. Ac-Nle-Pro-Nle -Asp AMC also inhibits the release of inflammatory factors from c2c12 myotubes, which may be due to its ability to block ubiquitin ligases.

Fórmula: C₃₃H₄₅N₅O₉

Pureza: Min. 97 Area-%

Cor e Forma: Powder

Peso molecular: 655.74 g/mol

Ref: 3D-FA110588

Ac-Nle-Pro-Nle-Asp-AMC

CAS: 355140-49-7

(S)-3-((S)-2-((S)-1-((S)-2-Acetamidohexanoyl)pyrrolidine-2-carboxamido)hexanamido)-4-((4-methyl-2-oxo-2H-chromen-7-yl)amino)-4-oxobutanoic acid

Fórmula: C₃₃H₄₅N₅O₉

Pureza: 98%

Peso molecular: 655.74

Ref: IN-DG01165363