CAS 3562-84-3

benzbromarona

Descrição:

benzbromarona é um composto orgânico sintético usado principalmente como um agente uricosúrico no tratamento da gota e da hiperuricemia. Funciona inibindo a reabsorção do ácido úrico nos rins, promovendo assim sua excreção. O composto é caracterizado por sua fórmula molecular, que inclui um grupo bromobenzeno, contribuindo para suas propriedades farmacológicas. benzbromarona é tipicamente administrado por via oral e é conhecido por sua relativamente alta biodisponibilidade. Apresenta solubilidade moderada a alta em solventes orgânicos, mas é menos solúvel em água. O composto tem uma longa meia-vida, permitindo a dosagem uma vez ao dia em ambientes clínicos. Os efeitos colaterais podem incluir distúrbios gastrointestinais e, em casos raros, toxicidade hepática, necessitando monitoramento da função hepática durante o tratamento. O mecanismo de ação e a eficácia de benzbromarona fazem dele uma opção valiosa no manejo de condições associadas a níveis elevados de ácido úrico, embora seu uso possa ser limitado por potenciais efeitos adversos e contraindicações em certas populações de pacientes.

Fórmula: C₁₇H₁₂Br₂O₃

InChI: InChI=1/C17H12Br2O3/c1-2-13-15(10-5-3-4-6-14(10)22-13)16(20)9-7-11(18)17(21)12(19)8-9/h3-8,21H,2H2,1H3

Chave InChI: InChIKey=WHQCHUCQKNIQEC-UHFFFAOYSA-N

SMILES: C(=O)(C=1C=2C(OC1CC)=CC=CC2)C3=CC(Br)=C(O)C(Br)=C3

Sinónimos:

• (3,5-Dibromo-4-hydroxyphenyl)(2-ethyl-3-benzofuranyl)methanone
• (3,5-Dibromo-4-hydroxyphenyl)(2-ethylbenzofuran-3-yl)methanone
• (3,5-Dibromo-4-hydroxyphenyl)-(2-ethyl-1-benzofuran-3-yl)methanone
• 2-Ethyl-3-(3,5-dibromo-4-hydroxybenzoyl)benzofuran
• 3,5-Dibromo-4-Hydroxyphenyl-2-Ethylbenzo[B]Furan-3-Yl Ketone
• 3,5-Dibromo-4-hydroxyphenyl 2-ethyl-3-benzofuranyl ketone
• Azubromaron
• Benzbromaron
• Besuric
• Desuric
• Ketone, 3,5-dibromo-4-hydroxyphenyl 2-ethyl-3-benzofuranyl
• L 2214
• L 2214-Labaz
• Max-Uric
• Methanone, (3,5-dibromo-4-hydroxyphenyl)(2-ethyl-3-benzofuranyl)-
• Minuric
• Mj 10061
• NSC 85433
• Narcaricin
• Normurat
• Uricovac
• Urinorm
• Benzbromarone
• mj10061
• BENZBROMARONE, MM(CRM STANDARD)
• l2214-labaz
• exurate
• l2214
• (3,5-dibromo-4-hydroxyphenyl)(2-ethyl-3-benzofuranyl)-methanon
• 3-(3,5-dibromo-4-hydroxybenzoyl)-2-ethyl-benzofura
• (3,5-Dibromo-4-hydroxyphenyl)(2-ethylbenzofuran-3-yl)ketone
• LABOTEST-BB LT00134669
• 3,5-dibromo-4-hydroxyphenyl2-ethyl-3-benzofuranylketone
• 3-[3,5-DIBROMO-4-HYDROXYBENZOYL]-2-ETHYLBENZOFURAN
• ketone,3,5-dibromo-4-hydroxyphenyl2-ethyl-3-benzofuranyl

Benzbromarone

CAS: 3562-84-3

Fórmula: C₁₇H₁₂Br₂O₃

Pureza: >98.0%(GC)(T)

Cor e Forma: White to Light yellow powder to crystal

Peso molecular: 424.09

Ref: 3B-B4099

BENZBROMARONE CRS

CAS: 3562-84-3

BENZBROMARONE CRS

Fórmula: C₁₇H₁₂Br₂O₃

Cor e Forma: Added Modified

Peso molecular: 424.0834

Ref: 41-Y0000775

Benzbromarone

CAS: 3562-84-3

Benzbromarone (Desuric) is a CYP2C9 inhibitor with Ki value of 19.3 nM.

Fórmula: C₁₇H₁₂Br₂O₃

Pureza: 99.37% - 99.94%

Cor e Forma: Solid

Peso molecular: 424.08

Ref: TM-T1274

Benzbromarone

CAS: 3562-84-3

Benzbromarone

Fórmula: C₁₇H₁₂Br₂O₃

Pureza: 99.5%

Peso molecular: 424.08

Ref: 54-BUP17025

Benzbromarone

CAS: 3562-84-3

Fórmula: C₁₇H₁₂Br₂O₃

Peso molecular: 424.09

Ref: 4Z-B-079003

Benzbromarone

CAS: 3562-84-3

Fórmula: C₁₇H₁₂Br₂O₃

Pureza: (GC) ≥ 98.0%

Cor e Forma: White to pale yellow powder or crystals

Peso molecular: 424.08

Ref: 7W-GP8819

Benzbromarone-d5

CAS: 3562-84-3

Fórmula: C₁₇H₇D₅Br₂O₃

Peso molecular: 429.12

Ref: 4Z-B-079013

Benzbromarone

CAS: 3562-84-3

Benzbromarone

Fórmula: C₁₇H₁₂Br₂O₃

Pureza: >98%

Cor e Forma: Solid

Peso molecular: 424.08

Ref: 54-OR1012321

Methanone, (3,5-dibromo-4-hydroxyphenyl)(2-ethyl-3-benzofuranyl)-

CAS: 3562-84-3

Fórmula: C₁₇H₁₂Br₂O₃

Pureza: 95%

Cor e Forma: Solid

Peso molecular: 424.0834

Ref: IN-DA003AX3

Benzbromarone

Produto Controlado

CAS: 3562-84-3

Fórmula: C₁₇H₁₂Br₂O₃

Cor e Forma: Neat

Peso molecular: 424.08

Ref: 86-MM0456.00

Benzbromarone

Produto Controlado

CAS: 3562-84-3

Fórmula: C₁₇H₁₂Br₂O₃

Cor e Forma: Neat

Peso molecular: 424.08

Ref: 04-C10534000

Benzbromarone-D5

Produto Controlado

CAS: 3562-84-3

Fórmula: C₁₇D₅H₇Br₂O₃

Cor e Forma: Neat

Peso molecular: 429.114

Ref: TR-B185202

Benzbromarone

Produto Controlado

CAS: 3562-84-3

Applications Benzbromarone is a uricosuric agent used in the treatment of gout and hyperuricemia. Studies show that use of Benzbromarone results in less complications than other uricosuric agent such as Allopurinol.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Heel, R.C. et al.: Drugs, 14, 349 (1977); Perez-Ruiz, F. et al.: Ann. Rheum. Dis., 57, 545 (1998);

Fórmula: C₁₇H₁₂Br₂O₃

Cor e Forma: Neat

Peso molecular: 424.08

Ref: TR-B185200

(3,5-Dibromo-4-hydroxyphenyl)(2-ethylbenzofuran-3-yl)methanone

CAS: 3562-84-3

(3,5-Dibromo-4-hydroxyphenyl)(2-ethylbenzofuran-3-yl)methanone

Fórmula: C₁₇H₁₂Br₂O₃

Pureza: 98%

Peso molecular: 424.08

Ref: IN-DG33371

Benzbromarone-d4

CAS: 3562-84-3

Fórmula: C₁₇H₈D₄Br₂O₃

Peso molecular: 428.11

Ref: 4Z-B-079011

(3,5-Dibromo-4-hydroxyphenyl)(2-ethyl-3-benzofuranyl)methanone

CAS: 3562-84-3

3,5-Dibromo-4-hydroxyphenyl-(2-ethyl-3-benzofuranyl)methanone (DBF) is a synthetic molecule that has been shown to be effective against obesity by reducing the size of fat cells. DBF was originally developed as an anti-inflammatory drug for psoriasis and arthritis. It has also been shown to have antioxidant and anti-cancer properties. DBF binds to toll-like receptor 4 (TLR4), which is involved in the inflammatory response, and inhibits its activation. This inhibition leads to a decrease in proinflammatory cytokines such as tumor necrosis factor alpha (TNFα). DBF also reduces the mitochondrial membrane potential, which may be due to its ability to inhibit ATP production by mitochondria and/or block mitochondrial protein synthesis.

Fórmula: C₁₇H₁₂Br₂O₃

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 424.08 g/mol

Ref: 3D-FD18180

Benzbromarone

CAS: 3562-84-3

Fórmula: C₁₇H₁₂Br₂O₃

Cor e Forma: Solid

Peso molecular: 424.1

Ref: BE-BePure-28875

Benzbromarone

CAS: 3562-84-3

Fórmula: C₁₇H₁₂Br₂O₃

Cor e Forma: Solid

Peso molecular: 424.1

Ref: BE-RMCB051000

Benzbromarone

CAS: 3562-84-3

Pureza: 95%

Peso molecular: 421.915

Ref: 10-F811899

Benzbromarone

CAS: 3562-84-3

Fórmula: C₁₇H₁₂Br₂O₃

Peso molecular: 424.08

Ref: ST-EA-CP-B46000