CAS 35661-60-0
:Fmoc-leucina
Descrição:
Fmoc-leucina, ou fluorenilmetoxicarbonila-leucina, é um derivado do aminoácido leucina, comumente utilizado na síntese de peptídeos e na síntese de peptídeos em fase sólida (SPPS). Apresenta um grupo protetor Fmoc que permite a desproteção seletiva durante o processo de síntese. A estrutura de Fmoc-leucina inclui um grupo fluorenilmetoxicarbonila ligado ao grupo amino da leucina, o que ajuda a estabilizar o aminoácido durante a síntese e previne reações indesejadas. Fmoc-leucina é tipicamente um sólido branco a off-white e é solúvel em solventes orgânicos como dimetilformamida (DMF) e dimetilsulfóxido (DMSO), mas menos solúvel em água. Seu uso na síntese de peptídeos é favorecido devido à facilidade de remoção do grupo Fmoc em condições básicas suaves, permitindo a adição sequencial de aminoácidos. Além disso, Fmoc-leucina mantém as propriedades essenciais da leucina, como sua natureza hidrofóbica, tornando-o valioso no design de peptídeos com características estruturais e funcionais específicas.
Fórmula:C21H23NO4
InChI:InChI=1S/C21H23NO4/c1-13(2)11-19(20(23)24)22-21(25)26-12-18-16-9-5-3-7-14(16)15-8-4-6-10-17(15)18/h3-10,13,18-19H,11-12H2,1-2H3,(H,22,25)(H,23,24)/t19-/m0/s1
Chave InChI:InChIKey=CBPJQFCAFFNICX-IBGZPJMESA-N
SMILES:C(OC(N[C@@H](CC(C)C)C(O)=O)=O)C1C=2C(C=3C1=CC=CC3)=CC=CC2
Sinónimos:- (2S)-2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-4-methylpentanoic acid
- (2S)-2-[[[(9H-Fluoren-9-yl)methoxy]carbonyl]amino]-4-methylpentanoic acid
- (S)-N-Fmoc-leucine
- 217: PN: US20070042401 PAGE: 29 claimed protein
- 908: PN: WO2006135786 PAGE: 58 claimed protein
- <span class="text-smallcaps">L</span>-Leucine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-
- Fmoc-<span class="text-smallcaps">L</span>-Leucine
- Fmoc-leucine
- N-(9-Fluorenylmethoxycarbonyl)-<span class="text-smallcaps">L</span>-leucine
- N-(9-Fluorenylmethoxycarbonyl)-L-leucine
- N-(9-Fluorenylmethoxycarbonyl)leucine
- N-(Fluorenylmethoxycarbonyl)leucine
- N-FMOC-leucine
- N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-<span class="text-smallcaps">L</span>-leucine
- N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-leucin
- N-[(9H-fluoren-9-ilmetoxi)carbonil]-L-leucina
- N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-leucine
- N-[(9H-fluorene-9-ylmethoxy)carbonyl]-L-leucine
- Npc 15199
- Nsc 334290
- (2S)-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-4-methylpentanoate
- Fmoc-L-Leu-OH
- L-Leucine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-
- Fmoc-L-Leucine
- (2R)-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-4-methylpentanoate
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N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-leucine
CAS:Fórmula:C21H23NO4Pureza:>98.0%(HPLC)(T)Cor e Forma:White to Almost white powder to crystalPeso molecular:353.42Fmoc-Leu-OH
CAS:M03365 - Fmoc-Leu-OH
Fórmula:C21H23NO4Pureza:98%Cor e Forma:SolidPeso molecular:353.418N-Fmoc-L-leucine, 98%
CAS:This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo SciFórmula:C21H23NO4Pureza:98%Cor e Forma:White, PowderPeso molecular:353.42Fmoc-Leu-OH
CAS:Fmoc-Leu-OH (NPC 15199, NSC 334290) showed anti-inflammatory activity. On histologic examination after administration of arachidonic acid, NPC 15199 was found to block the recruitment of neutrophils into the inflammatory site. Fmoc-L-leucine was effective in blocking antigen arthritis in rabbits.Fórmula:C21H23NO4Pureza:99.95%Cor e Forma:WhitePeso molecular:353.42Fmoc-Leu-OH
CAS:Fórmula:C21H23NO4Pureza:≥ 99.0%Cor e Forma:White to almost white powderPeso molecular:353.42L-Leucine-d10-N-FMOC
CAS:Fórmula:(CD3)2CDCD2CD(NHFMOC)COOHPureza:98 atom % DCor e Forma:White SolidPeso molecular:363.48L-Leucine-d3-N-FMOC(methyl-d3)
CAS:Fórmula:CH3CH(CD3)CH2CH(NHFMOC)COOHPureza:99 atom % DCor e Forma:White SolidPeso molecular:356.44Ref: IN-DA00I72W
5g20,00€10g20,00€25g28,00€50g38,00€100g52,00€250g99,00€500g141,00€1kg216,00€5kg565,00€10kg1.036,00€25kg2.642,00€L-Leucine, FMOC protected
CAS:L-Leucine, FMOC protectedFórmula:C21H23NO4Pureza:98%Cor e Forma:White SolidPeso molecular:353.41162NPC 15199
CAS:NPC 15199 (FMOC-L-Leucine) is an anti-inflammatory agent.Fórmula:C21H23NO4Pureza:99.93% - 99.94%Cor e Forma:White SolidPeso molecular:353.41Fmoc-Leu-OH
CAS:Fmoc-Leu-OH is a fatty acid that has been shown to be effective in treating inflammatory diseases such as skin cancer. It has also been shown to have neuroprotective and anti-inflammatory activities, which may be due to its ability to inhibit the nitrite levels in diabetic patients. Fmoc-Leu-OH has been shown to increase insulin sensitivity and decrease insulin resistance in diabetic patients. This drug may also have an effect on cancer by inhibiting the growth of tumor cells and inducing apoptosis.Fórmula:C21H23NO4Pureza:Min. 98.0 Area-%Peso molecular:353.41 g/molFmoc-Leu-OH
CAS:Fmoc-Leu-OH is a fatty acid that contains a hydroxyl group. It is used in the synthesis of polymer drugs, especially sodium salt polymers. The activity of Fmoc-Leu-OH can be reversed with degarelix acetate, an irreversible inhibitor of ns3 protease. In addition to its use as an antidiabetic agent, Fmoc-Leu-OH has been shown to have immunomodulatory effects and antiinflammatory activity. In tumor treatment, Fmoc-Leu-OH has been shown to inhibit the growth of fat cells without affecting normal cells or causing any toxic side effects.Fórmula:C21H23NO4Pureza:Min. 98 Area-%Cor e Forma:White PowderPeso molecular:353.41 g/molFMOC-L-Leucine extrapure, 99%
CAS:Fórmula:C21H23NO4Pureza:min. 99%Cor e Forma:White to Off white, Crystalline powderPeso molecular:353.40
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