CAS 366789-02-8
:Rivaroxabana
Descrição:
Rivaroxabana é um medicamento anticoagulante oral utilizado principalmente para a prevenção e tratamento de distúrbios tromboembólicos, como trombose venosa profunda e embolia pulmonar. Funciona como um inibidor direto do fator Xa, que interrompe a cascata de coagulação e reduz a formação de coágulos sanguíneos. Rivaroxabana é caracterizado por sua alta biodisponibilidade e farmacocinética previsível, permitindo dosagem fixa sem a necessidade de monitoramento rotineiro dos parâmetros de coagulação. A substância é tipicamente administrada em forma de comprimido e é absorvida rapidamente, com concentrações plasmáticas máximas ocorrendo dentro de algumas horas após a ingestão. É metabolizada principalmente no fígado através das enzimas do citocromo P450 e é excretada por vias renais e fecais. Efeitos colaterais comuns podem incluir complicações hemorrágicas, o que exige cautela em pacientes com certos fatores de risco. O perfil de eficácia e segurança de Rivaroxabana fez dele uma opção amplamente utilizada na terapia anticoagulante, embora seja contraindicado em pacientes com hemorragia ativa ou comprometimento renal severo.
Fórmula:C19H18ClN3O5S
InChI:InChI=1/C19H18ClN3O5S/c20-16-6-5-15(29-16)18(25)21-9-14-10-23(19(26)28-14)13-3-1-12(2-4-13)22-7-8-27-11-17(22)24/h1-6,14H,7-11H2,(H,21,25)/t14-/m0/s1
Chave InChI:InChIKey=KGFYHTZWPPHNLQ-AWEZNQCLSA-N
SMILES:O=C1N(C[C@H](CNC(=O)C=2SC(Cl)=CC2)O1)C3=CC=C(C=C3)N4C(=O)COCC4
Sinónimos:- (S)-Rivaroxaban
- 2-Thiophenecarboxamide, 5-chloro-N-[[(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]-
- 5-Chloro-N-(((5S)-2-oxo-3-(4-(3-oxomorpholin-4-yl)phenyl)-1,3-oxazolidin-5-yl)methyl)thiophene-2-carboxamide
- 5-Chloro-N-([(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidin-5-yl]-methyl)-2-thiophenecarboxamide
- 5-Chloro-N-[[(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]-2-thiophenecarboxamide
- 5-Chloro-N-[[(S)-3-(4-(3-oxomorpholin-4-yl)phenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl]-thiophene-2-carboxamide
- 5-chloro-N-[[(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]oxazolidin-5-yl]methyl]thiophene-2-carboxamide
- Bay 59-7939
- Rivaroxaban intermediates
- Rivaroxban
- Xarelto
- Rivaroxaban
- (S)-5-chloro-N-((2-oxo-3-(4-(3-oxomorpholino)phenyl)oxazolidin-5-yl)methyl)thiophene-2-carboxamide
- Rivaroxaban API
- Rivarobaxan
- Rivaroxaban(Xarelto)
- (S)-5-Chloro-N-((2-oxo-3-(4-(3-oxomorpholino)phenyl)-oxazolidin-5-yl)methyl)thiophene-2-carboxami
- Rivaroxaba
- Ver mais sinónimos
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14 produtos.
Rivaroxaban
CAS:Fórmula:C19H18ClN3O5SPureza:>98.0%(T)(HPLC)Cor e Forma:White to Light yellow powder to crystalPeso molecular:435.88Rivaroxaban
CAS:Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoiFórmula:C19H18ClN3O5SCor e Forma:White PowderPeso molecular:435.06557Rivaroxaban
CAS:Rivaroxaban (BAY 59-7939) is an oral, direct factor Xa inhibitor with anticoagulant properties, interfering with thrombin formation.Fórmula:C19H18ClN3O5SPureza:99.93% - >99.99%Cor e Forma:SolidPeso molecular:435.885-chloro-N-{[(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl]methyl}thiophene-2-carboxamide
CAS:Fórmula:C19H18ClN3O5SPureza:99%Cor e Forma:SolidPeso molecular:435.8813Rivaroxaban
CAS:Fórmula:C19H18ClN3O5SPureza:≥ 98.0% (dried basis)Cor e Forma:White to off-white powderPeso molecular:435.88Rivaroxaban
CAS:<p>Applications A novel antithrombotic agent. A highly potent and selective, direct FXa inhibitor.<br>References Ansell, J., et al.: Drugs, 64, 1 (2004), Eriksson, B., et al.: J. Thromb. Haemost., 3, 103 (2005), Kubitza, D., et al.: Clin. Pharmacol. Ther., 78, 412 (2005),<br></p>Fórmula:C19H18ClN3O5SCor e Forma:White To BeigePeso molecular:435.88Rivaroxaban - Bio-X ™
CAS:<p>Rivaroxaban is a natural drug that is a direct factor Xa inhibitor. It has been shown to be an effective therapy for the treatment of atrial fibrillation, deep vein thrombosis (DVT) and pulmonary embolism (PE). It works by inhibiting the enzyme, thrombin, which is responsible for the formation of blood clots. Rivaroxaban also has an effect on the coagulation system by decreasing the levels of fibrinogen and increases in antithrombin III. This drug does not have any specific antidote, but it can be reversed with heparin. Pharmacodynamics and drug interactions have been studied extensively in preclinical models, demonstrated by the concentration–time curves.</p>Fórmula:C19H18ClN3O5SPureza:Min. 95%Cor e Forma:White PowderPeso molecular:435.88 g/molRivaroxaban
CAS:<p>Rivaroxaban is a natural drug that is a direct factor Xa inhibitor. It has been shown to be an effective therapy for the treatment of atrial fibrillation, deep vein thrombosis (DVT) and pulmonary embolism (PE). It works by inhibiting the enzyme, thrombin, which is responsible for the formation of blood clots. Rivaroxaban also has an effect on the coagulation system by decreasing the levels of fibrinogen and increases in antithrombin III. This drug does not have any specific antidote, but it can be reversed with heparin. Pharmacodynamics and drug interactions have been studied extensively in preclinical models, demonstrated by the concentration–time curves.</p>Fórmula:C19H18ClN3O5SPureza:Min. 98 Area-%Cor e Forma:White Off-White PowderPeso molecular:435.88 g/mol
![5-chloro-N-{[(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl]methyl}thiophene-2-c…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA0035KL.jpg&w=3840&q=75)
