CAS 38819-10-2

2-amino-9-(beta-D-arabinofuranosil)-3,9-diidro-6H-purina-6-ona

Descrição:

2-amino-9-(beta-D-arabinofuranosil)-3,9-diidro-6H-purina-6-ona, comumente conhecido como Ara-A ou arabinosiladenina, é um análogo de nucleosídeo com notáveis propriedades antivirais. É caracterizado por sua estrutura de base purínica, que inclui um grupo amino na posição 2 e um moiety de açúcar beta-D-arabinofuranosilo. Este composto exibe uma estereoquímica única que contribui à sua atividade biológica, particularmente na inibição da replicação viral. Ara-A é utilizado principalmente no tratamento de infecções virais, incluindo aquelas causadas pelo vírus herpes simplex e outros vírus de RNA. Seu mecanismo de ação envolve a interferência na síntese de ácidos nucleicos virais, tornando-o um agente terapêutico valioso. O composto é tipicamente administrado em sua forma de fosfato para melhorar a solubilidade e a biodisponibilidade. Além disso, Ara-A tem sido estudado por seu potencial na terapia do câncer devido à sua capacidade de interromper processos celulares. No geral, suas características estruturais e atividades biológicas fazem dele um composto significativo na química medicinal e na virologia.

Fórmula: C₁₀H₁₃N₅O₅

InChI: InChI=1/C10H13N5O5/c11-10-13-7-4(8(19)14-10)12-2-15(7)9-6(18)5(17)3(1-16)20-9/h2-3,5-6,9,16-18H,1H2,(H3,11,13,14,19)/t3-,5-,6+,9-/m1/s1

Chave InChI: InChIKey=NYHBQMYGNKIUIF-FJFJXFQQSA-N

SMILES: O=C1C2=C(N(C=N2)[C@@H]3O[C@H](CO)[C@@H](O)[C@@H]3O)NC(N)=N1

Sinónimos:

• 1-β-D-Arabinofuranosylguanine
• 2-Amino-6-hydroxy-9-(β-<span class="text-smallcaps">D</span>-arabinofuranosyl)purine
• 2-Amino-9-(beta-D-arabinofuranosyl)-1,9-dihydro-6H-purin-6-one
• 2-Amino-9-β-<span class="text-smallcaps">D</span>-arabinofuranosyl-1,9-dihydro-6H-purin-6-one
• 6H-Purin-6-one, 2-amino-9-β-<span class="text-smallcaps">D</span>-arabinofuranosyl-1,9-dihydro-
• 6H-purin-6-one, 2-amino-9-beta-D-arabinofuranosyl-1,9-dihydro-
• 9-(Beta-D-Arabinofuranosyl)Guanine
• 9-Arabinoguanine
• 9-β-<span class="text-smallcaps">D</span>-Arabinofuranosylguanine
• A 4233
• Arabinoguanosine
• Araguanosine
• Guanine arabinoside
• Guanine, 9-β-<span class="text-smallcaps">D</span>-arabinofuranosyl-
• NSC 76352
• ara-Guanosine
• Arabinosylguanine
• 9-β-D-Arabinofuranosylguanine
• Guanine, 9-β-D-arabinofuranosyl-
• 2-Amino-6-hydroxy-9-(β-D-arabinofuranosyl)purine
• 6H-Purin-6-one, 2-amino-9-β-D-arabinofuranosyl-1,9-dihydro-
• 2-Amino-9-β-D-arabinofuranosyl-1,9-dihydro-6H-purin-6-one
• )-21-(Acetyloxy)-9,11-epoxy-6-fluoro-16-methyl-d3-pregna-1,4-diene-3,20-dione
• )-10-Bromo-8,9,10,11-tetrahydrobenz[a]anthracene-8,9,11-triol
• 9-beta-D-Arabinofuranosylguanine Hydrate
• GUANINE-9-ARABINOSIDE
• -Epoxy-21dehydroxy Betamethasone
• Ara-G
• 9-β-D-Arabinofuranosyl-1,6-dihydro-2-amino-6-oxo-9H-purine
• 9-beta-Arabinosylguanine
• )-9,11-Epoxy-pregna-1,4,16-triene-3,20-dione
• 9-(β-D-Arabinoribofuranosyl)-guanine
• 9-arabinofuranosylguanine
• 9-(BETA-D-ARABINOFURANOSYL)GUANINE USP/EP/BP
• 9-(b-D-Arabinofuranosyl)guanine
• 9-β-D-Arabinofuranosyl-2-amino-9H-purin-6-ol
• )-9,11-Epoxy-6-fluoro-21-hydroxy-16-methyl-pregna-1,4-diene-3,20-dione
• 9-β-D-Arabinofuranosylguanine Hydrate
• 2-AMino-9-((2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxyMethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one
• )-21-(Acetyloxy)-9,11-epoxy-6-fluoro-17-hydroxy-16-methylpregna-1,4-diene-3,20-dione
• -Epoxy-17,21-dihydroxy-16&beta
• 2-amino-9-beta-d-arabinofuranosyl-1,9-dihydro-6h-purin-6-on
• Guanine, 9-(beta-D-arabinofuranosyl)-
• 9-β-D-Arabinofuranosylguanine Hydrate &gt
• 9-&beta
• 9-(beta-d-arabinofuranosyl)-guanin
• )-9,11-Epoxy-1,21-dihydroxy-4,16-dimethyl-19-norpregna-1,3,5(10)-trien-20-one
• 9-(β-D-Arabinofuranosyl)guanine ,97%
• )-9,11-Epoxy-21-hydroxy-16-methyl-pregna-1,4-diene-3,20-dione
• )-21-(Acetyloxy)-9,11-epoxypregna-1,4,16-triene-3,20-dione
• 2-Amino-9-β-D-arabinofuranosyl-9H-purine-6(1H)-one
• Ara-G hydrate, 98%, inhibitor of DNA synthesis, an antimetabolite and antineoplastic.
• Ara-G hydrate
• -Arabinofuranosylguanine Hydrate
• 2-amino-9-(beta-D-arabinofuranosyl)-3,9-dihydro-6H-purin-6-one
• ARABINOFURANOSYL-GUANINE
• D
• -
• )-9-Bromo-8,9,10,11-tetrahydrobenz[a]anthracene-8,10,11-triol-d9
• Arabinofuranosyl-guanine (ara-G)
• )-21-(Acetyloxy)-9,11-epoxy-6-fluoro-pregna-1,4,16-triene-3,20-dione
• 9-β-D-Arabinofuranosyl guanine hydrate
• -methyl-pregn-4-ene-3,20-dione
• )-9,11-Epoxy-6-fluoropregna-1,4,16-triene-3,20-dione
• ARA-G 9-(BETA-D-ARABINOFURANOSYL)-GUANINE

9-beta-D-Arabinofuranosylguanine

CAS: 38819-10-2

Fórmula: C₁₀H₁₃N₅O₅

Pureza: >98.0%(HPLC)

Cor e Forma: White to Almost white powder to crystal

Peso molecular: 283.24

Ref: 3B-A2739

9-β-Arabinosylguanine

CAS: 38819-10-2

9-β-Arabinosylguanine

Fórmula: C₁₀H₁₃N₅O₅

Pureza: 98%

Peso molecular: 283.24

Ref: 54-OR1026312

Ara-G

CAS: 38819-10-2

Ara-G

Fórmula: C₁₀H₁₃N₅O₅

Pureza: 98.5%

Peso molecular: 283.24

Ref: 54-BUP16058

9-β-D-Arabinofuranosylguanine

CAS: 38819-10-2

Fórmula: C₁₀H₁₃N₅O₅

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 283.2407

Ref: IN-DA0037XI

9-β-D-Arabinofuranosylguanine

CAS: 38819-10-2

9-beta-Arabinosylguanine

Fórmula: C₁₀H₁₃N₅O₅

Pureza: 98%

Peso molecular: 283.24

Ref: IN-DG12134

Ara-G

CAS: 38819-10-2

Ara-G, a deoxyguanosine analog, inhibits DNA synthesis, targeting T cell leukemia by converting to araGTP.

Fórmula: C₁₀H₁₃N₅O₅

Pureza: 98.74%

Cor e Forma: White Solid

Peso molecular: 283.2407

Ref: TM-T36944

Nelarabine Impurity 16

CAS: 38819-10-2

Fórmula: C₁₀H₁₃N₅O₅

Peso molecular: 283.24

Ref: 4Z-N-5217

9-(b-D-Arabinofuranosyl)guanine

CAS: 38819-10-2

Fórmula: C₁₀H₁₃N₅O₅·xH₂O

Pureza: ≥ 97.5%

Cor e Forma: White to off-white crystalline powder

Peso molecular: 283.24 (anhydrous)

Ref: 7W-GN2070

9-(b-D-Arabinofuranosyl)guanine

CAS: 38819-10-2

9-(b-D-Arabinofuranosyl)guanine is an arabinoside derivative that has high affinity for DNA. 9-(b-D-Arabinofuranosyl)guanine binds to the phosphate groups in DNA and inhibits the synthesis of DNA. It is used in vitro assays to study molecular pathogenesis and in vivo as a drug against leukemia, lymphomas, and other cancers. 9-(b-D-Arabinofuranosyl)guanine also inhibits protein synthesis by binding to ribosomes. This drug can cause significant side effects such as gastrointestinal distress, diarrhea, nausea, vomiting, and abdominal pain. It can also cause blood dyscrasias and liver damage.

Fórmula: C₁₀H₁₃N₅O₅

Pureza: Min. 97 Area-%

Cor e Forma: White Powder

Peso molecular: 283.24 g/mol

Ref: 3D-NA06002

Ara-G

CAS: 38819-10-2

Fórmula: C₁₀H₁₃N₅O₅

Peso molecular: 283.24

Ref: BE-RMCN045008

9-β-D-Arabinofuranosylguanine

CAS: 38819-10-2

Pureza: 98%

Peso molecular: 283.092

Ref: 10-F858517

9-b-D-Arabinofuranosylguanine

CAS: 38819-10-2

Fórmula: C₁₀H₁₃N₅O₅

Pureza: 95.0%

Cor e Forma: Liquid, No data available.

Peso molecular: 283.244

Ref: 10-F225628

Ara-G

Produto Controlado

CAS: 38819-10-2

Applications Ara-G is an inducer of apoptosis, inhibitor of DNA synthesis, an antimetabolite, and antineoplastic.

Fórmula: C₁₀H₁₃N₅O₅

Cor e Forma: Neat

Peso molecular: 283.24

Ref: TR-A765558

Ara-G-13C,15N2

Produto Controlado

CAS: 38819-10-2

Fórmula: CC₉H₁₃₁₅N₂N₃O₅

Cor e Forma: Neat

Peso molecular: 286.22

Ref: TR-A765559

Nelarabine Impurity 16

CAS: 38819-10-2

Fórmula: C₁₀H₁₃N₅O₅

Peso molecular: 283.24

Ref: ST-EA-CP-N38018

9-(b-D-Arabinofuranosyl)guanine

CAS: 38819-10-2

Fórmula: C₁₀H₁₃N₅O₅

Peso molecular: 283.24

Ref: ST-EA-CP-A88013

9-(b-D-Arabinofuranosyl)guanine - Bio-X ™

CAS: 38819-10-2

9-(b-D-Arabinofuranosyl) guanine is a purine nucleoside in which guanine is attached to arabinofuranose via a beta-N(9)-glycosidic bond. 9-(b-D-Arabinofuranosyl) guanine binds to the phosphate groups in DNA and inhibits the synthesis of DNA causing cell death. It also has antineoplastic properties.

Fórmula: C₁₀H₁₃N₅O₅

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 283.24 g/mol

Ref: 3D-BA300152