CAS 39012-20-9

Picroside II

Descrição:

Picroside II é um composto glicósido derivado principalmente da raiz da planta *Picrorhiza kurroa*, conhecida por suas propriedades medicinais na medicina tradicional. É caracterizado por seu sabor amargo e frequentemente estudado por seus potenciais efeitos terapêuticos, incluindo atividades hepatoprotetoras, anti-inflamatórias e antioxidantes. A estrutura química de Picroside II consiste em uma porção de glicose ligada a uma aglicona fenólica, contribuindo para sua atividade biológica. Este composto é solúvel em água e solventes orgânicos, tornando-o versátil para várias aplicações em formulações herbais e pesquisa farmacológica. Além disso, Picroside II despertou interesse por seu potencial papel no tratamento de distúrbios hepáticos e na melhoria da função imunológica. Seu perfil de segurança e eficácia são temas de pesquisa em andamento, destacando a importância de entender sua farmacocinética e mecanismos de ação no contexto da medicina herbal. No geral, Picroside II representa um composto significativo no estudo de produtos naturais e suas aplicações em saúde e bem-estar.

Fórmula: C₂₃H₂₈O₁₃

InChI: InChI=1/C23H28O13/c1-31-12-6-9(2-3-11(12)26)20(30)34-18-10-4-5-32-21(14(10)23(8-25)19(18)36-23)35-22-17(29)16(28)15(27)13(7-24)33-22/h2-6,10,13-19,21-22,24-29H,7-8H2,1H3/t10?,13-,14?,15-,16+,17-,18?,19?,21?,22+,23?/m1/s1

Chave InChI: InChIKey=AKNILCMFRRDTEY-UHFFFAOYSA-N

SMILES: C(O)C12C(O1)C(OC(=O)C3=CC(OC)=C(O)C=C3)C4C2C(OC5OC(CO)C(O)C(O)C5O)OC=C4

Sinónimos:

• (1aS,1bS,2S,5aR,6S,6aS)-1a,1b,2,5a,6,6a-Hexahydro-6-[(4-hydroxy-3-methoxybenzoyl)oxy]-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl β-<span class="text-smallcaps">D</span>-glucopyranoside
• 2-(Hexopyranosyloxy)-1A-(Hydroxymethyl)-1A,1B,2,5A,6,6A-Hexahydrooxireno[4,5]Cyclopenta[1,2-C]Pyran-6-Yl 4-Hydroxy-3-Methoxybenzoate
• 2-(beta-D-glucopyranosyloxy)-1a-(hydroxymethyl)-1a,1b,2,5a,6,6a-hexahydrooxireno[4,5]cyclopenta[1,2-c]pyran-6-yl 4-hydroxy-3-methoxybenzoate
• Amphicoside II
• Ampicoside
• Kutkin II
• Oxireno[4,5]cyclopenta[1,2-c]pyran, β-<span class="text-smallcaps">D</span>-glucopyranoside deriv.
• Picroside II
• Vanilloyl catalpol
• beta-D-Glucopyranoside, 1a,1b,2,5a,6,6a-hexahydro-6-((4-hydroxy-3-methoxybenzoyl)oxy)-1a-(hydroxymethyl)oxireno(4,5)cyclopenta(1,2-c)pyran-2-yl, (1aS-(1aalpha,1bbeta,2beta,5abeta,6beta,6aalpha))-
• β-<span class="text-smallcaps">D</span>-Glucopyranoside, (1aS,1bS,2S,5aR,6S,6aS)-1a,1b,2,5a,6,6a-hexahydro-6-[(4-hydroxy-3-methoxybenzoyl)oxy]-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl
• β-<span class="text-smallcaps">D</span>-Glucopyranoside, 1a,1b,2,5a,6,6a-hexahydro-6-[(4-hydroxy-3-methoxybenzoyl)oxy]-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl, [1aS-(1aα,1bβ,2β,5aβ,6β,6aα)]-
• β-D-Glucopyranoside, 1a,1b,2,5a,6,6a-hexahydro-6-[(4-hydroxy-3-methoxybenzoyl)oxy]-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl, [1aS-(1aα,1bβ,2β,5aβ,6β,6aα)]-
• Oxireno[4,5]cyclopenta[1,2-c]pyran, β-D-glucopyranoside deriv.
• (1aS,1bS,2S,5aR,6S,6aS)-1a,1b,2,5a,6,6a-Hexahydro-6-[(4-hydroxy-3-methoxybenzoyl)oxy]-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl β-D-glucopyranoside
• β-D-Glucopyranoside, (1aS,1bS,2S,5aR,6S,6aS)-1a,1b,2,5a,6,6a-hexahydro-6-[(4-hydroxy-3-methoxybenzoyl)oxy]-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl
• (1aS-(1aalpha,1bbeta,2beta,5abeta,6beta,6aalpha))-1a,1b,2,5a,6,6a-Hexahydro-6-((4-hydroxy-3-methoxybenzoyl)oxy)-1a-(hydroxymethyl)oxireno(4,5)cyclopenta(1,2-c)pyran-2-yl-beta-D-glucopyranoside
• PICROSID II
• Berberine II
• 6-[(4-hydroxy-3-methoxybenzoyl)oxy]-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl,[1aS-(1aα,1bβ,2β,5aβ,6β,6aα)]-
• Picroside a…
• Picroside II, 98%, from Picrorhiza scrophulariiflora Pennell.
• 6'-VANILLOYL CATALPOL
• Picroside II, ≥98% (HPLC)
• Picroside II USP/EP/BP
• AMPHICOSIDE
• PICROSIDE ò
• Picroside-2

Picroside II

CAS: 39012-20-9

Fórmula: C₂₃H₂₈O₁₃

Pureza: 97%

Cor e Forma: Solid

Peso molecular: 512.4606

Ref: IN-DA00BYG2

Picroside II

CAS: 39012-20-9

Picroside II

Pureza: ≥98%

Peso molecular: 512.46g/mol

Ref: 54-BUP13396

Picroside 2

CAS: 39012-20-9

Fórmula: C₂₃H₂₈O₁₃

Pureza: ≥ 98.0%

Cor e Forma: White, off-white or pale yellow powder

Peso molecular: 512.47

Ref: 7W-GC2669

(1aS,1bS,2S,5aR,6S,6aS)-1A-(Hydroxymethyl)-2-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-2-Yl)Oxy)-1A,1B,2,5A,6,6A-Hexahydrooxireno[2’,3’:4,5]Cyclopenta[1,2-C]Pyran-6-Yl4-

CAS: 39012-20-9

(1aS,1bS,2S,5aR,6S,6aS)-1A-(Hydroxymethyl)-2-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-2-Yl)Oxy)-1A,1B,2,5A,6,6A-Hexahydrooxireno[2’,3’:4,5]Cyclopenta[1,2-C]Pyran-6-Yl4-

Pureza: 95%

Peso molecular: 512.46g/mol

Ref: 54-OR1025805

Picroside II

CAS: 39012-20-9

Fórmula: C₂₃H₂₈O₁₃

Pureza: >98.0%(HPLC)(qNMR)

Cor e Forma: White to Light yellow powder to crystal

Peso molecular: 512.46

Ref: 3B-P2594

Picroside II

CAS: 39012-20-9

Picroside II has antioxidant, anti-inflammatory, immune regulatory, anti-virus and other pharmacological activities. It has potent anti-apoptotic activity against renal I/R injury by suppressing the TLR4/NF-κB signaling pathway, it can protect the ischemic kidney against renal fibrosis and improve the neurological function of rats upon cerebral ischemia reperfusion injury. Picroside II enhances nerve growth factor (NGF)-induced neurite outgrowth from PC12D cells by amplifying a down-stream step of MAP kinase in the NGF receptor-mediated intracellular MAP kinase-dependent signaling pathway.

Fórmula: C₂₃H₂₈O₁₃

Pureza: 95%~99%

Peso molecular: 512.464

Ref: BP-BP1100

Picroside II

CAS: 39012-20-9

Picroside II (Vanilloyl catalpol) is the main active ingredient in iridoid glycosides.

Fórmula: C₂₃H₂₈O₁₃

Pureza: 98% - 99.83%

Cor e Forma: Solid

Peso molecular: 512.46

Ref: TM-T2817

Picroside ii

CAS: 39012-20-9

Natural glycoside

Fórmula: C₂₃H₂₈O₁₃

Pureza: ≥ 90.0 % (HPLC)

Cor e Forma: Powder

Peso molecular: 512.47

Ref: 5G-89759

Picroside II

Produto Controlado

CAS: 39012-20-9

Applications Picroside II similar to Picroside I (P437635), acts as an oxygen free radical scavenger and thus promotes anti-inflammatory activity and may be used in the treatment of arthritis or ischemic injury.
References Wang, Y. et al.: Res. Neuro. Int. J., 488911, 8 (2014); Singh, G. et al.: Phytother. Res., 7, 402 (1993); Chander R. et al.: Biochem. Pharmacol., 7, 190 (1992);

Fórmula: C₂₃H₂₈O₁₃

Cor e Forma: Neat

Peso molecular: 512.46

Ref: TR-P437640

Picroside 2

CAS: 39012-20-9

Picroside 2 is a natural iridoid glycoside, which is derived from the medicinal plant Picrorhiza kurroa. This bioactive compound is primarily extracted from the roots and rhizomes of the plant, known for its significant therapeutic properties. Picroside 2 functions mainly through its antioxidative and anti-inflammatory mechanisms, offering protection against oxidative stress and mitigating liver damage. By inhibiting various inflammatory mediators and pathways, it contributes to cellular protection and promotes regeneration.

Fórmula: C₂₃H₂₈O₁₃

Pureza: Min. 95%

Peso molecular: 512.47 g/mol

Ref: 3D-MP10468

Picroside II

CAS: 39012-20-9

Pureza: 97%

Peso molecular: 512.153

Ref: 10-F869650