CAS 39012-20-9

Picroside II

Descrição:

Picroside II é um composto glicósido derivado principalmente da raiz da planta *Picrorhiza kurroa*, conhecida por suas propriedades medicinais na medicina tradicional. É caracterizado por seu sabor amargo e frequentemente estudado por seus potenciais efeitos terapêuticos, incluindo atividades hepatoprotetoras, anti-inflamatórias e antioxidantes. A estrutura química de Picroside II consiste em uma porção de glicose ligada a uma aglicona fenólica, contribuindo para sua atividade biológica. Este composto é solúvel em água e solventes orgânicos, tornando-o versátil para várias aplicações em formulações herbais e pesquisa farmacológica. Além disso, Picroside II despertou interesse por seu potencial papel no tratamento de distúrbios hepáticos e na melhoria da função imunológica. Seu perfil de segurança e eficácia são temas de pesquisa em andamento, destacando a importância de entender sua farmacocinética e mecanismos de ação no contexto da medicina herbal. No geral, Picroside II representa um composto significativo no estudo de produtos naturais e suas aplicações em saúde e bem-estar.

Fórmula: C₂₃H₂₈O₁₃

InChI: InChI=1/C23H28O13/c1-31-12-6-9(2-3-11(12)26)20(30)34-18-10-4-5-32-21(14(10)23(8-25)19(18)36-23)35-22-17(29)16(28)15(27)13(7-24)33-22/h2-6,10,13-19,21-22,24-29H,7-8H2,1H3/t10?,13-,14?,15-,16+,17-,18?,19?,21?,22+,23?/m1/s1

Chave InChI: InChIKey=AKNILCMFRRDTEY-UHFFFAOYSA-N

SMILES: C(O)C12C(O1)C(OC(=O)C3=CC(OC)=C(O)C=C3)C4C2C(OC5OC(CO)C(O)C(O)C5O)OC=C4

Sinónimos:

• (1aS,1bS,2S,5aR,6S,6aS)-1a,1b,2,5a,6,6a-Hexahydro-6-[(4-hydroxy-3-methoxybenzoyl)oxy]-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl β-<span class="text-smallcaps">D</span>-glucopyranoside
• 2-(Hexopyranosyloxy)-1A-(Hydroxymethyl)-1A,1B,2,5A,6,6A-Hexahydrooxireno[4,5]Cyclopenta[1,2-C]Pyran-6-Yl 4-Hydroxy-3-Methoxybenzoate
• 2-(beta-D-glucopyranosyloxy)-1a-(hydroxymethyl)-1a,1b,2,5a,6,6a-hexahydrooxireno[4,5]cyclopenta[1,2-c]pyran-6-yl 4-hydroxy-3-methoxybenzoate
• Amphicoside II
• Ampicoside
• Kutkin II
• Oxireno[4,5]cyclopenta[1,2-c]pyran, β-<span class="text-smallcaps">D</span>-glucopyranoside deriv.
• Picroside II
• Vanilloyl catalpol
• beta-D-Glucopyranoside, 1a,1b,2,5a,6,6a-hexahydro-6-((4-hydroxy-3-methoxybenzoyl)oxy)-1a-(hydroxymethyl)oxireno(4,5)cyclopenta(1,2-c)pyran-2-yl, (1aS-(1aalpha,1bbeta,2beta,5abeta,6beta,6aalpha))-
• β-<span class="text-smallcaps">D</span>-Glucopyranoside, (1aS,1bS,2S,5aR,6S,6aS)-1a,1b,2,5a,6,6a-hexahydro-6-[(4-hydroxy-3-methoxybenzoyl)oxy]-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl
• β-<span class="text-smallcaps">D</span>-Glucopyranoside, 1a,1b,2,5a,6,6a-hexahydro-6-[(4-hydroxy-3-methoxybenzoyl)oxy]-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl, [1aS-(1aα,1bβ,2β,5aβ,6β,6aα)]-
• β-D-Glucopyranoside, 1a,1b,2,5a,6,6a-hexahydro-6-[(4-hydroxy-3-methoxybenzoyl)oxy]-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl, [1aS-(1aα,1bβ,2β,5aβ,6β,6aα)]-
• Oxireno[4,5]cyclopenta[1,2-c]pyran, β-D-glucopyranoside deriv.
• (1aS,1bS,2S,5aR,6S,6aS)-1a,1b,2,5a,6,6a-Hexahydro-6-[(4-hydroxy-3-methoxybenzoyl)oxy]-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl β-D-glucopyranoside
• β-D-Glucopyranoside, (1aS,1bS,2S,5aR,6S,6aS)-1a,1b,2,5a,6,6a-hexahydro-6-[(4-hydroxy-3-methoxybenzoyl)oxy]-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl
• (1aS-(1aalpha,1bbeta,2beta,5abeta,6beta,6aalpha))-1a,1b,2,5a,6,6a-Hexahydro-6-((4-hydroxy-3-methoxybenzoyl)oxy)-1a-(hydroxymethyl)oxireno(4,5)cyclopenta(1,2-c)pyran-2-yl-beta-D-glucopyranoside
• PICROSID II
• Berberine II
• 6-[(4-hydroxy-3-methoxybenzoyl)oxy]-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl,[1aS-(1aα,1bβ,2β,5aβ,6β,6aα)]-
• Picroside a…
• Picroside II, 98%, from Picrorhiza scrophulariiflora Pennell.
• 6'-VANILLOYL CATALPOL
• Picroside II, ≥98% (HPLC)
• Picroside II USP/EP/BP
• AMPHICOSIDE
• PICROSIDE ò
• Picroside-2

Picroside II

CAS: 39012-20-9

Fórmula: C₂₃H₂₈O₁₃

Pureza: >98.0%(HPLC)(qNMR)

Cor e Forma: White to Light yellow powder to crystal

Peso molecular: 512.46

Ref: 3B-P2594

Picroside 2

CAS: 39012-20-9

Fórmula: C₂₃H₂₈O₁₃

Pureza: ≥ 98.0%

Cor e Forma: White, off-white or pale yellow powder

Peso molecular: 512.47

Ref: 7W-GC2669

Picroside II

CAS: 39012-20-9

Picroside II

Fórmula: C₂₃H₂₈O₁₃

Pureza: 95%

Peso molecular: 512.46

Ref: 54-OR1025805

Picroside II

CAS: 39012-20-9

Picroside II

Fórmula: C₂₃H₂₈O₁₃

Pureza: 98.5%

Peso molecular: 512.46

Ref: 54-BUP13396

Picroside II

CAS: 39012-20-9

Picroside II has antioxidant, anti-inflammatory, immune regulatory, anti-virus and other pharmacological activities. It has potent anti-apoptotic activity against renal I/R injury by suppressing the TLR4/NF-κB signaling pathway, it can protect the ischemic kidney against renal fibrosis and improve the neurological function of rats upon cerebral ischemia reperfusion injury. Picroside II enhances nerve growth factor (NGF)-induced neurite outgrowth from PC12D cells by amplifying a down-stream step of MAP kinase in the NGF receptor-mediated intracellular MAP kinase-dependent signaling pathway.

Fórmula: C₂₃H₂₈O₁₃

Pureza: 95%~99%

Peso molecular: 512.464

Ref: BP-BP1100

Picroside II (Standard)

CAS: 39012-20-9

Picroside II (Standard) is a reference standard for research and analysis in studies involving Picroside II. Picroside II (Vanilloyl catalpol) is the main active ingredient in iridoid glycosides. It has antioxidant, anti-inflammatory, immune regulatory, anti-virus and other pharmacological activities.

Fórmula: C₂₃H₂₈O₁₃

Peso molecular: 512.4606

Ref: TM-TMSM-1805

Picroside II

Produto Controlado

CAS: 39012-20-9

Applications Picroside II similar to Picroside I (P437635), acts as an oxygen free radical scavenger and thus promotes anti-inflammatory activity and may be used in the treatment of arthritis or ischemic injury.
References Wang, Y. et al.: Res. Neuro. Int. J., 488911, 8 (2014); Singh, G. et al.: Phytother. Res., 7, 402 (1993); Chander R. et al.: Biochem. Pharmacol., 7, 190 (1992);

Fórmula: C₂₃H₂₈O₁₃

Cor e Forma: Neat

Peso molecular: 512.46

Ref: TR-P437640

Picroside II

CAS: 39012-20-9

Picroside II (Vanilloyl catalpol) is the main active ingredient in iridoid glycosides.

Fórmula: C₂₃H₂₈O₁₃

Pureza: 98% - 99.83%

Cor e Forma: Solid

Peso molecular: 512.4606

Ref: TM-T2817

Picroside II

CAS: 39012-20-9

(1aS,1bS,2S,5aR,6S,6aS)-1a-(Hydroxymethyl)-2-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-1a,1b,2,5a,6,6a-hexahydrooxireno[2',3':4,5]cyclopenta[1,2-c]pyran-6-yl 4-hydroxy-3-methoxybenzoate

Fórmula: C₂₃H₂₈O₁₃

Pureza: 95%

Peso molecular: 512.46

Ref: IN-DG33504

Picroside II

CAS: 39012-20-9

Natural glycoside

Fórmula: C₂₃H₂₈O₁₃

Pureza: ≥ 90.0 % (HPLC)

Cor e Forma: Powder

Peso molecular: 512.47

Ref: 5G-89759

Picroside-II

CAS: 39012-20-9

Fórmula: C₂₃H₂₈O₁₃

Peso molecular: 512.5

Ref: BE-RMT12180

Picroside II

CAS: 39012-20-9

Pureza: 97%

Peso molecular: 512.153

Ref: 10-F869650

Picroside II

CAS: 39012-20-9

Fórmula: C₂₃H₂₈O₁₃

Pureza: 95%

Cor e Forma: Solid

Peso molecular: 512.4606

Ref: IN-DA00BYG2