CAS 39562-70-4

Nitrendipina

Descrição:

Nitrendipina é um bloqueador de canais de cálcio utilizado principalmente no tratamento da hipertensão e da angina de peito. Pertence à classe de compostos dihidropiridínicos, que se caracterizam pela sua capacidade de inibir seletivamente a entrada de cálcio através dos canais de cálcio tipo L no músculo liso vascular e no tecido cardíaco. Essa ação leva à vasodilatação e a uma subsequente diminuição da pressão arterial. Nitrendipina é conhecido por sua alta lipofilicidade, que melhora sua absorção e distribuição no corpo. O composto geralmente apresenta uma longa meia-vida, permitindo a dosagem uma vez ao dia em ambientes clínicos. Sua estrutura química inclui um grupo nitro, que contribui para suas propriedades farmacológicas. Nitrendipina é geralmente bem tolerado, mas como outros bloqueadores de canais de cálcio, pode causar efeitos colaterais como dor de cabeça, rubor ou edema periférico. Assim como qualquer medicamento, é importante considerar contraindicações e potenciais interações com outros fármacos. No geral, Nitrendipina é um agente eficaz no manejo de condições cardiovasculares, contribuindo para a melhoria dos resultados dos pacientes.

Fórmula: C₁₈H₂₀N₂O₆

InChI: InChI=1/C18H20N2O6/c1-5-26-18(22)15-11(3)19-10(2)14(17(21)25-4)16(15)12-7-6-8-13(9-12)20(23)24/h6-9,15-16H,5H2,1-4H3/t15?,16-/m1/s1

Chave InChI: InChIKey=PVHUJELLJLJGLN-UHFFFAOYSA-N

SMILES: C(OCC)(=O)C=1C(C(C(OC)=O)=C(C)NC1C)C2=CC(N(=O)=O)=CC=C2

Sinónimos:

• (.+-.)-Bay E 5009
• (.+-.)-Nitrendipine
• 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 3-ethyl 5-methyl ester
• Baylotensin
• Bayotensin
• Baypress
• Bylotensin
• Cardif
• Deiten
• Nidrel
• Nitrendipin
• Nitrendipino
• Nitrepin
• 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, ethyl methyl ester
• 3-ethyl 5-methyl (4S)-2,6-dimethyl-4-(3-nitrophenyl)-3,4-dihydropyridine-3,5-dicarboxylate
• 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid ethyl methyl ester
• 3-ethyl 5-methyl (4R)-2,6-dimethyl-4-(3-nitrophenyl)-3,4-dihydropyridine-3,5-dicarboxylate
• ethyl methyl 1,4-dihydro-2,6-dimethyl-4-(meta-nitrophenyl)-3,5-pyridinedicarboxylate
• NITRENDIPINE IMPURITY AETHYL METHYL-2,6-DIMETHYL-4-(3-NITROPHENYL) PYRIDINE-3,5-DICARBOXYLATE
• ylmethylester
• NITRENDIPINE EPN(CRM STANDARD)
• (NITROPHENYLPYRIDINE ANALOGUE) EPN(CRM STANDARD)
• 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, ethyl methyl ester (9CI)
• NITRENDIPINE >95% CA2+ CHANNEL BLOCKER,
• ethylmethyl1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)-3,5-pyridinedicarboxy
• 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylicacidethy
• NITRENDIPINE MM(CRM STANDARD)
• baye5009

Nitrendipine

CAS: 39562-70-4

Fórmula: C₁₈H₂₀N₂O₆

Pureza: >98.0%(HPLC)(N)

Cor e Forma: White to Yellow powder to crystal

Peso molecular: 360.37

Ref: 3B-N1186

Nitrendipine

CAS: 39562-70-4

L-type calcium channel blocker

Fórmula: C₁₈H₂₀N₂O₆

Cor e Forma: Powder

Peso molecular: 360.37

Ref: 02-J60841

NITRENDIPINE FOR PEAK IDENTIFICATION CRS

CAS: 39562-70-4

NITRENDIPINE FOR PEAK IDENTIFICATION CRS

Fórmula: C₁₈H₂₀N₂O₆

Peso molecular: 360.3612

Ref: 41-Y0001456

NITRENDIPINE CRS

CAS: 39562-70-4

NITRENDIPINE CRS

Fórmula: C₁₈H₂₀N₂O₆

Peso molecular: 360.3612

Ref: 41-N0905000

Nitrendipine

CAS: 39562-70-4

Fórmula: C₁₈H₂₀N₂O₆

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 360.3612

Ref: IN-DA003T4X

Nitrendipine

CAS: 39562-70-4

Nitrendipine

Fórmula: C₁₈H₂₀N₂O₆

Pureza: >98%

Peso molecular: 360.36

Ref: 54-OR1030253

Nitrendipine

CAS: 39562-70-4

Nitrendipine is a vasodilating calcium channel blocker and antihypertensive that preserves kidney function and promotes sodium excretion.

Fórmula: C₁₈H₂₀N₂O₆

Pureza: 99% - 99.55%

Cor e Forma: Solid

Peso molecular: 360.36

Ref: TM-T0119

Nitrendipine

CAS: 39562-70-4

Nitrendipine

Fórmula: C₁₈H₂₀N₂O₆

Pureza: ≥98%

Peso molecular: 360.36

Ref: 54-BUP15672

Nitrendipine

CAS: 39562-70-4

Fórmula: C₁₈H₂₀N₂O₆

Pureza: ≥ 97.0%

Cor e Forma: Pale yellow to yellow or green powder

Peso molecular: 360.36

Ref: 7W-GP6940

Nitrendipine (Lercanidipine EP Impurity B)

CAS: 39562-70-4

Fórmula: C₁₈H₂₀N₂O₆

Peso molecular: 360.37

Ref: 4Z-N-060002

Nitrendipine

CAS: 39562-70-4

Cor e Forma: Neat

Ref: 61-FOR0092.00

Nitrendipine

Produto Controlado

CAS: 39562-70-4

Fórmula: C₁₈H₂₀N₂O₆

Cor e Forma: Neat

Peso molecular: 360.36

Ref: 86-MM0092.00

NITRENDIPINE

CAS: 39562-70-4

Pureza: 95+%

Peso molecular: 360.3659973

Ref: 10-F813117

Nitrendipine (Standard)

CAS: 39562-70-4

Nitrendipine (Standard) is the standard substance of Nitrendipine, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Nitrendipine (BAY-E-5009) is a calcium channel blocker with marked vasodilator action. It is an effective antihypertensive agent and differs from other calcium channel blockers in that it does not reduce glomerular filtration rate and is mildly natriuretic, rather than sodium retentive.

Fórmula: C₁₈H₂₀N₂O₆

Peso molecular: 360.36

Ref: TM-TMSM-1739

Nitrendipine 100 µg/mL in Acetonitrile

CAS: 39562-70-4

Fórmula: C₁₈H₂₀N₂O₆

Cor e Forma: Single Solution

Peso molecular: 360.36

Ref: 04-A15529500AL-100

Nitrendipine

CAS: 39562-70-4

3-Ethyl 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

Fórmula: C₁₈H₂₀N₂O₆

Pureza: 98%

Peso molecular: 360.36

Ref: IN-DG20623

Nitrendipine

Produto Controlado

CAS: 39562-70-4

Applications Nitrendipine is a dihydropyridine calcium channel blocker. Nitrendipine is used in the treatment of primary (essential) hypertension to decrease blood pressure. Antihypertensive.
References Ventura, H.O., et al.: Am. J. Cardiol., 51, 783 (1983); Kann, J. et al.: Brit. J. Clin. Pharmacol., 33, 51 (1992);

Fórmula: C₁₈H₂₀N₂O₆

Cor e Forma: Neat

Peso molecular: 360.36

Ref: TR-N490150

Nitrendipine-d5

Produto Controlado

CAS: 39562-70-4

Applications Nitrendipine-d5 is the isotope labelled analogue of Nitrendipine (N490150), a dihydropyridine calcium channel blocker. Nitrendipine is used in the treatment of primary (essential) hypertension to decrease blood pressure. Antihypertensive.
References Ventura, H.O., et al.: Am. J. Cardiol., 51, 783 (1983),

Fórmula: C₁₈H₁₅D₅N₂O₆

Cor e Forma: Neat

Peso molecular: 365.39

Ref: TR-N490152

(RS)-Methyl ethyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate

CAS: 39562-70-4

Methyl ethyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate is a propranolol hydrochloride derivative that has vasodilatory effects. It is used as a nitrovasodilator to treat angina pectoris and high blood pressure. Methyl ethyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate binds to the alpha1 adrenergic receptors in the heart and causes vasodilation by inhibiting the release of norepinephrine from sympathetic nerves. This drug also inhibits the binding of norepinephrine to cardiac beta receptors which decreases the heart rate and contractility of cardiac muscle. Methyl ethyl 1,4-dihydro-2,6

Fórmula: C₁₈H₂₀N₂O₆

Pureza: Min. 95%

Cor e Forma: Yellow Powder

Peso molecular: 360.36 g/mol

Ref: 3D-IM57947

(RS)-Methyl ethyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate - EP Grade

CAS: 39562-70-4

Propranolol hydrochloride is a non-selective beta-adrenergic blocker that blocks the effects of epinephrine, norepinephrine and dopamine. Propranolol hydrochloride has been shown to inhibit the activity of proximal tubules in the kidney, which may be due to its inhibition of chemical ionization. This drug also has antihypertensive activity and can be used for the treatment of cardiac disorders such as hypertension. Propranolol hydrochloride is a monoclonal antibody that is activated by nitro groups and binds with high affinity to multiple-reaction monitoring (MRM) transitions for protonated molecular ions at m/z 289, 296, 305, 313, 320, 328, 336 and 344. Propranolol hydrochloride also has vasodilatory effects on the papillary muscle which aids in regulating blood pressure by maintaining vascular resistance.

Fórmula: C₁₈H₂₀N₂O₆

Pureza: Min. 95%

Peso molecular: 360.36 g/mol

Ref: 3D-IM175687