CAS 4773-96-0
:Mangiferina
Descrição:
Mangiferina é um composto polifenólico que ocorre naturalmente, encontrado principalmente em mangas e várias outras plantas, particularmente na família Anacardiaceae. É classificado como um glicosídeo de xantona, caracterizado por sua estrutura complexa que inclui um núcleo de xantona ligado a uma unidade de glicose. Mangiferina exibe uma variedade de atividades biológicas, incluindo propriedades antioxidantes, anti-inflamatórias e antimicrobianas, tornando-o de interesse na pesquisa farmacológica. Sua fórmula química é C17H17O11, e tem um peso molecular de aproximadamente 433,31 g/mol. Mangiferina é solúvel em água e solventes orgânicos, o que melhora sua biodisponibilidade. O composto foi estudado por seus potenciais efeitos terapêuticos, incluindo seu papel no manejo de distúrbios metabólicos, doenças cardiovasculares e certos tipos de câncer. Além disso, o perfil de segurança de Mangiferina foi avaliado, indicando baixos níveis de toxicidade em vários estudos. No geral, Mangiferina representa uma área significativa de interesse na química de produtos naturais e na pesquisa medicinal devido aos seus diversos benefícios e aplicações para a saúde.
Fórmula:C19H18O11
InChI:InChI=1S/C19H18O11/c20-4-11-15(25)17(27)18(28)19(30-11)12-8(23)3-10-13(16(12)26)14(24)5-1-6(21)7(22)2-9(5)29-10/h1-3,11,15,17-23,25-28H,4H2/t11-,15-,17+,18-,19+/m1/s1
Chave InChI:InChIKey=AEDDIBAIWPIIBD-ZJKJAXBQSA-N
SMILES:OC1=C2C(OC=3C(C2=O)=CC(O)=C(O)C3)=CC(O)=C1[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O
Sinónimos:- (1S)-1,5-anhydro-1-(1,3,6,7-tetrahydroxy-9-oxo-9H-xanthen-2-yl)-D-glucitol
- (1xi)-1,5-anhydro-1-(1,3,6,7-tetrahydroxy-9-oxo-9H-xanthen-2-yl)-D-glucitol
- 1,3,6,7-Tetrahydroxyxanthone-C<sub>2</sub>-β-<span class="text-smallcaps">D</span>-glucoside
- 1,5-anhydro-1-(1,3,6,7-tetrahydroxy-9-oxo-9H-xanthen-2-yl)hexitol
- 2-C-β-<span class="text-smallcaps">D</span>-Glucopyranosyl-1,3,6,7-tetrahydroxyxanthone
- 2-β-<span class="text-smallcaps">D</span>-Glucopyranosyl-1,3,6,7-tetrahydroxy-9H-xanthen-9-one
- 9H-Xanthen-9-one, 2-β-<span class="text-smallcaps">D</span>-glucopyranosyl-1,3,6,7-tetrahydroxy-
- Alpizarin
- Alpizarine
- Aphloiol
- Chinomin
- Chinonin
- Hedysarid
- Mangiferin
- NSC 248870
- Shamimin
- Xanthone-c-glucoside
- 2-β-D-Glucopyranosyl-1,3,6,7-tetrahydroxy-9H-xanthen-9-one
- Ver mais sinónimos
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Pureza (%)
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100
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90
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95
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100
Foram encontrados 19 produtos.
Mangiferin
CAS:Fórmula:C19H18O11Pureza:>97.0%(T)(HPLC)Cor e Forma:White to Light orange to Pale yellow green powder to crystalPeso molecular:422.34Mangiferin
CAS:Mangiferin analytical standard provided with w/w absolute assay, to be used for quantitative titration.Fórmula:C19H18O11Pureza:(HPLC) ≥99%Cor e Forma:PowderPeso molecular:422.35MANGIFERIN CRS
CAS:MANGIFERIN CRSFórmula:C19H18O11Cor e Forma:Light Yellow. Powder.Peso molecular:422.3396Mangiferin
CAS:Other glycosides, natural or reproduced by synthesis, and their salts, ethers, esters and other derivativesFórmula:C19H18O11Cor e Forma:Yellow Green SolidPeso molecular:422.08491Mangifera Indica Bark Dry Extract
CAS:Vegetable saps and extracts, nesoiCor e Forma:Reddish-Brown PowderMangiferin
CAS:Mangiferin (Hedysarid) is used for antidiabetes. Extracted from Mangifera indica L.Fórmula:C19H18O11Pureza:99.78% - 99.86%Cor e Forma:Yellow SolidPeso molecular:422.349H-Xanthen-9-one, 2-b-D-glucopyranosyl-1,3,6,7-tetrahydroxy-
CAS:Fórmula:C19H18O11Pureza:98%Cor e Forma:SolidPeso molecular:422.3396Mangiferin Mangifera Indica
CAS:Mangiferin Mangifera IndicaFórmula:C19H18O11Pureza:95%Peso molecular:422.34Mangiferin
CAS:Mangiferin (MF) and its glucosides (mangiferin-7-O-beta-glucoside) (MG) isolated from Anemarrhena asphodeloides Bunge rhizome, have antidiabetic activity in KK-Ay mice,Fórmula:C19H18O11Pureza:95%~99%Cor e Forma:PowderPeso molecular:422.3421,3,6,7-Tetrahydroxyxanthone-C2-b-D-glucoside
CAS:Fórmula:C19H18O11Pureza:≥ 95.0%Cor e Forma:Off-white to yellow powderPeso molecular:422.34Mangiferin
CAS:Natural glycosideFórmula:C19H18O11Pureza:≥ 95.0 % (HPLC)Cor e Forma:PowderPeso molecular:422.35Mangiferin
CAS:Produto ControladoApplications Mangiferin is a xanthonoid, a chemical compound found in mangoes and in Anemarrhena asphodeloides rhizomes. Mangiferin has effect of hepatinica and choleretic, and is used to therapy hepatitis. Mangiferin is an anti-inflammatory, antivirotic, central nervous system inhibit function and immunologic suppression. Mangiferin has curative effect on chronic bronchitis. Mangiferin has cytotoxicity effect on hepatocellularcarcinoma ce1l, and may induce apoptosis. Mangiferin has the effect of antioxidation and delaying caducity.
References Tawab, M., et al.; Drug Metab. Dispos., 31, 1065 (2003), Yim, J., et al.: Biol. Pharm. Bull., 27, 1580 (2004), Kim, Y., et al.: J. Microbiol. Biotechnol., 18, 1109 (2008), Joh, E., et al.: Biochem. Pharmacol., 82, 278 (2011),Fórmula:C19H18O11Cor e Forma:NeatPeso molecular:422.34Mangiferin - 90%
CAS:Mangiferin - 90% is a purified form of the bioactive compound mangiferin, which is a xanthonoid derived primarily from the leaves, bark, and fruit of the mango tree, Mangifera indica. Known for its potent antioxidant properties, mangiferin acts by scavenging free radicals, thereby protecting cells from oxidative stress and potential damage. This mode of action makes it a critical component in research focused on understanding its potential in mitigating oxidative stress-related conditions.Fórmula:C19H18O11Pureza:Min. 95%Cor e Forma:PowderPeso molecular:422.34 g/molMangiferin, 98%
CAS:Mangiferin is a monosodium salt of mangiferin and has been shown to have DNA-binding activity. It is an activator of the apoptosis pathway and has been shown to inhibit the dinucleotide phosphate (DNP) synthase enzyme, which is involved in nucleotide synthesis. This inhibition prevents cells from making DNA and RNA, leading to cell death. Mangiferin also has hypoglycemic effects in humans due to its ability to inhibit glycolysis. The biological properties of mangiferin are not well understood but it has been shown that it may be detoxified by enzymes such as cytochrome P450 or glutathione S-transferase. Mangiferin also exhibits anti-cancer activities against colorectal adenocarcinoma cells and human breast cancer cells MDA-MB-231. It acts by inhibiting dextran sulfate (DS) uptake, which is an important component for the proliferation of tumor cells.Fórmula:C19H18O11Pureza:Min. 95%Cor e Forma:PowderPeso molecular:422.34 g/molMangiferin
CAS:1,3,6,7-Tetrahydroxy-2-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)-9H-xanthen-9-oneFórmula:C19H18O11Pureza:98%Peso molecular:422.34
