CAS 4836-13-9

N4-benzoil-2'-desoxicitidina

Descrição:

N4-benzoil-2'-desoxicitidina, com o número CAS 4836-13-9, é um nucleosídeo modificado que apresenta um grupo benzóico ligado ao átomo de nitrogênio na posição 4 da base de citidina. Este composto é caracterizado por seus componentes estruturais, que incluem um açúcar de desoxirribose e uma base de pirimidina, especificamente citidina. A modificação benzóica aumenta sua lipofilicidade e pode influenciar sua atividade biológica, tornando-o de interesse na química medicinal e na biologia molecular. N4-benzoil-2'-desoxicitidina é frequentemente estudado por suas potenciais aplicações em terapias antivirais e anticancerígenas, uma vez que as modificações nos nucleosídeos podem afetar sua interação com ácidos nucleicos e enzimas. Além disso, este composto pode apresentar propriedades únicas de solubilidade e estabilidade em comparação com nucleosídeos não modificados, o que pode ser vantajoso na formulação e entrega de medicamentos. Sua síntese geralmente envolve a acilação de 2′-desoxi-citidina, e pode ser analisada usando várias técnicas espectroscópicas para confirmar sua estrutura e pureza.

Fórmula: C₁₆H₁₇N₃O₅

InChI: InChI=1/C16H17N3O5/c20-9-12-11(21)8-14(24-12)19-7-6-13(18-16(19)23)17-15(22)10-4-2-1-3-5-10/h1-7,11-12,14,20-21H,8-9H2,(H,17,18,22,23)/t11-,12+,14+/m1/s1

Chave InChI: InChIKey=MPSJHJFNKMUKCN-OUCADQQQSA-N

SMILES: O=C1N([C@@H]2O[C@H](CO)[C@@H](O)C2)C=CC(NC(=O)C3=CC=CC=C3)=N1

Sinónimos:

• 4-(benzoylamino)-1-(2-deoxy-beta-L-erythro-pentofuranosyl)pyrimidin-2(1H)-one
• 4-N-Benzoyldeoxycytidine
• Benzamide, N-[1-(2-deoxy-β-<span class="text-smallcaps">D</span>-erythro-pentofuranosyl)-1,2-dihydro-2-oxo-4-pyrimidinyl]-
• Cytidine, N-benzoyl-2′-deoxy-
• N-Benzoyl-2′-deoxycytidine
• N-Benzoyldeoxycytidine
• N4-Benzoyl-2'-deoxycytidine
• N⁴-Benzoyl-2′-deoxycytidine
• N⁴-Benzoyldeoxycytidine
• Benzamide, N-[1-(2-deoxy-β-D-erythro-pentofuranosyl)-1,2-dihydro-2-oxo-4-pyrimidinyl]-
• N4-Benzoyldeoxycytidine
• N-Benzoyl-2-Deoxy-Cytidine
• Bz-dC
• DC-N-BZ
• n-benzoyl-2’-deoxy-cytidin
• N(sup 4)benzoyl-2'-deoxycytidine
• NBZ-2'-DC
• N-BZ-DC
• N-[1-(2-Deoxy-β-D-ribofuranosyl)-2-oxo-1,2-dihydropyrimidine-4-yl]benzamide
• N4-BZ-2'-DEOXYCYTIDINE
• DC-BZ 99.0%
• 4-(Benzoylamino)-1-(2-deoxy-beta-L-erythro-pentofuranosyl)-2(1H)-pyrimidinone
• DC-BZ/N-BENZOYL-2''-DEOXY-CYTIDIN
• DC-BZ

N4-Benzoyl-2'-deoxycytidine

CAS: 4836-13-9

Fórmula: C₁₆H₁₇N₃O₅

Pureza: >98.0%(HPLC)(N)

Cor e Forma: White to Almost white powder to crystal

Peso molecular: 331.33

Ref: 3B-B3102

N-Benzoyl-2'-deoxycytidine, 98+%

CAS: 4836-13-9

N-Benzoyl-2'-deoxycytidine, 98+%

Fórmula: C₁₆H₁₇N₃O₅

Pureza: 98+%

Cor e Forma: White to pale cream, Powder or crystalline powder

Peso molecular: 331.33

Ref: 02-H52298

N4-Benzoyl-2′-deoxycytidine

CAS: 4836-13-9

N4-Benzoyl-2′-deoxycytidine

Fórmula: C₁₆H₁₇N₃O₅

Pureza: ≥98%

Peso molecular: 331.32

Ref: 54-BUP16481

N4-Benzoyl-2'-deoxycytidine

CAS: 4836-13-9

Fórmula: C₁₆H₁₇N₃O₅

Pureza: 97%

Cor e Forma: Solid

Peso molecular: 331.3233

Ref: IN-DA006WUB

N-Benzoyl-2-Deoxy-Cytidine

CAS: 4836-13-9

N-Benzoyl-2-Deoxy-Cytidine

Fórmula: C₁₆H₁₇N₃O₅

Pureza: 98%

Peso molecular: 331.32

Ref: 54-OR1014255

N4-Benzoyl-2''-deoxycytidine

CAS: 4836-13-9

Fórmula: C₁₆H₁₇N₃O₅

Peso molecular: 331.33

Ref: 7W-GN9700

N4-Benzoyl-2'-deoxycytidine

CAS: 4836-13-9

Pureza: 98.0%

Cor e Forma: Solid, No data available.

Peso molecular: 331.3280029296875

Ref: 10-F434668

N4-Benzoyl-2′-deoxycytidine

CAS: 4836-13-9

N4-Benzoyl-2′-deoxycytidine is a synthetic nucleoside analog of the natural nucleoside deoxycytidine (dC), a competitive inhibitor of DNA polymerase.

Fórmula: C₁₆H₁₇N₃O₅

Pureza: 99.41%

Cor e Forma: Solid

Peso molecular: 331.32

Ref: TM-T7961

N4-Benzoyl-2'-deoxycytidine

CAS: 4836-13-9

N4-Benzoyl-2'-deoxycytidine is a fluorescent nucleoside that has been used to study the molecular interactions between sugar residues and the phosphate groups of nucleic acids. It is used as a reagent for glycosidation, which involves the formation of a glycosidic linkage between an alcohol group in a saccharide or oligosaccharide and the hydroxyl group in an aromatic acid. N4-Benzoyl-2'-deoxycytidine has also been synthesized by solid-phase techniques. This synthetic method is based on phosphoramidite chemistry and uses an automated DNA synthesizer to produce oligonucleotides with specific sequences. The synthesis of this nucleoside relies on the use of fluorescent dyes such as fluorescein, rhodamine, and coumarin to monitor progress during synthesis.

Fórmula: C₁₆H₁₇N₃O₅

Pureza: Min. 95%

Cor e Forma: White Powder

Peso molecular: 331.33 g/mol

Ref: 3D-NB02991

N4-Benzoyl-2'-deoxy-a-cytidine

CAS: 4836-13-9

N4-Benzoyl-2'-deoxy-a-cytidine is a novel, modified nucleoside that has shown anticancer and antiviral activity. It is synthesized by the enzymatic oxidation of 2'-deoxyadenosine with benzoyl chloride and sodium bicarbonate. N4-Benzoyl-2'-deoxy-a-cytidine has been shown to activate transcription, increase DNA synthesis, and inhibit virus replication. It also inhibits bacterial growth, but does not appear to have any effect on mammalian cells.

Fórmula: C₁₆H₁₇N₃O₅

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 331.32 g/mol

Ref: 3D-NB08374

N-Benzoyldeoxycytidine

Produto Controlado

CAS: 4836-13-9

Applications N-Benzoyldeoxycytidine is proetected Deoxycytidine (2’-deoxy, D232615) which is a Eg5 kinesin modulator with antiproliferative and apoptosis-inducing activity.
References Hecht, S., et al.: Chem. Res. Toxicol., 17, 588 (2004), Choi, J., et al.: J. Biol. Chem., 281, 38244 (2006), Lao, Y., et al.: Chem. Res. Toxicol., 20, 246 (2007)

Fórmula: C₁₆H₁₇N₃O₅

Cor e Forma: Neat

Peso molecular: 331.32

Ref: TR-B208000