CAS 5041-81-6

Isoliquiritina

Descrição:

Isoliquiritina é um composto flavonoide derivado principalmente das raízes de Glycyrrhiza glabra, comumente conhecido como alcaçuz. É caracterizado por sua estrutura química, que inclui uma espinha dorsal de flavanona, contribuindo para suas várias atividades biológicas. Isoliquiritina exibe propriedades antioxidantes, ajudando a neutralizar radicais livres e reduzir o estresse oxidativo. Além disso, foi estudado por seus potenciais efeitos anti-inflamatórios, anticancerígenos e neuroprotetores, tornando-o de interesse na pesquisa farmacológica. O composto é solúvel em solventes orgânicos e possui um peso molecular relativamente baixo, o que facilita sua absorção em sistemas biológicos. Isoliquiritina também é notado por sua capacidade de modular certas vias de sinalização, o que pode contribuir para seus efeitos terapêuticos. Seu perfil de segurança é geralmente favorável, mas mais estudos são necessários para entender completamente sua farmacocinética e efeitos a longo prazo. No geral, Isoliquiritina representa um produto natural promissor com aplicações potenciais em saúde e medicina.

Fórmula: C₂₁H₂₂O₉

InChI: InChI=1/C21H22O9/c22-10-17-18(26)19(27)20(28)21(30-17)29-13-5-1-11(2-6-13)3-8-15(24)14-7-4-12(23)9-16(14)25/h1-9,17-23,25-28H,10H2/b8-3+/t17-,18-,19+,20-,21-/m1/s1

Chave InChI: InChIKey=YNWXJFQOCHMPCK-LXGDFETPSA-N

SMILES: O([C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)C2=CC=C(/C=C/C(=O)C3=C(O)C=C(O)C=C3)C=C2

Sinónimos:

• (2E)-1-(2,4-Dihydroxyphenyl)-3-[4-(β-<span class="text-smallcaps">D</span>-glucopyranosyloxy)phenyl]-2-propen-1-one
• 2-Propen-1-one, 1-(2,4-dihydroxyphenyl)-3-(4-(beta-D-glucopyranosyloxy)phenyl)-, (2E)-
• 2-Propen-1-one, 1-(2,4-dihydroxyphenyl)-3-[4-(β-<span class="text-smallcaps">D</span>-glucopyranosyloxy)phenyl]-, (2E)-
• 2-Propen-1-one, 1-(2,4-dihydroxyphenyl)-3-[4-(β-<span class="text-smallcaps">D</span>-glucopyranosyloxy)phenyl]-, (E)-
• 2′,4,4′-Trihydroxychalcone 4-(β-<span class="text-smallcaps">D</span>-glucopyranoside)
• Chalcone, 2′,4,4′-trihydroxy-, 4-β-<span class="text-smallcaps">D</span>-glucopyranoside
• Isoliquiritin
• Isoliquiritoside
• 2-Propen-1-one, 1-(2,4-dihydroxyphenyl)-3-[4-(β-D-glucopyranosyloxy)phenyl]-, (2E)-
• 2-Propen-1-one, 1-(2,4-dihydroxyphenyl)-3-[4-(β-D-glucopyranosyloxy)phenyl]-, (E)-
• (2E)-1-(2,4-Dihydroxyphenyl)-3-[4-(β-D-glucopyranosyloxy)phenyl]-2-propen-1-one
• Chalcone, 2′,4,4′-trihydroxy-, 4-β-D-glucopyranoside
• (E)-1-(2,4-Dihydroxyphenyl)-3-[4-(β-D-glucopyranosyloxy)phenyl]-2-propen-1-one
• [(E)-2',4'-Dihydroxychalcone-4-yl]β-D-glucopyranoside
• 4-[(1E)-3-(2,4-dihydroxyphenyl)-3-oxoprop-1-en-1-yl]phenyl beta-D-glucopyranoside
• Aids-004475
• 2',4,4'-Trihydroxychalcone 4-beta-D-glucopyranoside
• 2',4,4'-Trihydroxychalcone 4-(beta-D-glucopyranoside)
• neoisoliquritin

Isoliquiritin

CAS: 5041-81-6

Fórmula: C₂₁H₂₂O₉

Pureza: >98.0%(HPLC)

Cor e Forma: White to Yellow powder to crystal

Peso molecular: 418.40

Ref: 3B-I1144

Isoliquiritin

CAS: 5041-81-6

Fórmula: C₂₁H₂₂O₉

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 418.3940

Ref: IN-DA003R3X

Isoliquiritin

CAS: 5041-81-6

Isoliquiritin

Fórmula: C₂₁H₂₂O₉

Pureza: ≥98%

Cor e Forma: Solid

Peso molecular: 418.39

Ref: 54-BUP08910

Isoliquiritin

CAS: 5041-81-6

Insampaedoksan is a traditional herbal medicine used for antipyretic and antiinflammatory diseases, isoliquiritigenin is the main compound of it , thus , isoliquiritigenin has bioactivity effects such as antioxidant, estrogenic and anticancer.

Fórmula: C₂₁H₂₂O₉

Pureza: 95%~99%

Cor e Forma: Yellow powder

Peso molecular: 418.398

Ref: BP-BP0788

Isoliquiritin (Standard)

CAS: 5041-81-6

Isoliquiritin (Standard) is a reference standard for research and analysis in studies involving Isoliquiritin. 1. Isoliquiritin (Neoisoliquritin) has antitussive effects. 2. Isoliquiritin has antidepressant-like effects. 3. Isoliquiritin, liquiritin and isoliquirigenin inhibits the p53-dependent pathway and shows crosstalk between Akt activities.

Fórmula: C₂₁H₂₂O₉

Peso molecular: 418.394

Ref: TM-TMSM-3013

Isoliquiritin

CAS: 5041-81-6

Isoliquiritin analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Fórmula: C₂₁H₂₂O₉

Pureza: (HPLC) ≥99%

Cor e Forma: Powder

Peso molecular: 418.4

Ref: 11-1366S

Isoliquiritin

CAS: 5041-81-6

Isoliquiritin (Neoisoliquritin) has antitussive and antidepressant-like effects, and together with liquiritin and isoliquirigenin, it inhibits the p53-dependent pathway and exhibits crosstalk with Akt activities.

Fórmula: C₂₁H₂₂O₉

Pureza: 98.65% - 99.88%

Cor e Forma: Solid

Peso molecular: 418.394

Ref: TM-T5S0331

Isoliquiritin

CAS: 5041-81-6

Fórmula: C₂₁H₂₂O₉

Pureza: ≥ 95.0%

Cor e Forma: Light-yellow to dark yellow powder

Peso molecular: 418.40

Ref: 7W-GY1387

Isoliquiritin

CAS: 5041-81-6

Natural glycoside

Fórmula: C₂₁H₂₂O₉

Pureza: ≥ 90.0 % (HPLC)

Cor e Forma: Powder

Peso molecular: 418.4

Ref: 5G-80481

Isoliquiritin

CAS: 5041-81-6

Isoliquiritin is a bioactive compound, specifically a flavonoid, which is derived from the roots of Glycyrrhiza glabra, commonly known as licorice. It possesses diverse pharmacological properties with multiple modes of action, notably influencing pathways involved in oxidative stress and inflammation. Isoliquiritin acts as an antioxidant, scavenging free radicals and reducing oxidative damage at the cellular level. Additionally, it exhibits anti-inflammatory effects by modulating the expression of inflammatory cytokines and inhibiting specific signaling pathways like NF-κB.

Fórmula: C₂₁H₂₂O₉

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 418.39 g/mol

Ref: 3D-FN42767

Isoliquiritin

CAS: 5041-81-6

Fórmula: C₂₁H₂₂O₉

Peso molecular: 418.4

Ref: BE-RMT22109