CAS 51-48-9

(-)-Tiroxina

Descrição:

(-)-Tiroxina, também conhecido como L-tiroxina ou T4, é um hormônio produzido pela glândula tireoide que desempenha um papel crucial na regulação do metabolismo, crescimento e desenvolvimento no corpo. É um derivado tetraiodado do aminoácido tirosina, caracterizado pela presença de quatro átomos de iodo em sua estrutura. A fórmula química de (-)-Tiroxina é C15H11I4N0, e tem um peso molecular de aproximadamente 776,87 g/mol. Este composto é tipicamente encontrado como um pó cristalino branco a off-white e é solúvel em água e álcool, mas menos solúvel em solventes orgânicos. (-)-Tiroxina funciona ligando-se aos receptores de hormônios tireoidianos, influenciando a expressão gênica e os processos metabólicos. É comumente usado em ambientes clínicos para tratar o hipotireoidismo e outros distúrbios relacionados à tireoide. Sua atividade é monitorada de perto, pois tanto a deficiência quanto o excesso podem levar a problemas de saúde significativos. O número CAS 51-48-9 identifica exclusivamente este composto em bancos de dados químicos, facilitando a pesquisa e a conformidade regulatória.

Fórmula: C₁₅H₁₁I₄NO₄

InChI: InChI=1S/C15H11I4NO4/c16-8-4-7(5-9(17)13(8)21)24-14-10(18)1-6(2-11(14)19)3-12(20)15(22)23/h1-2,4-5,12,21H,3,20H2,(H,22,23)/t12-/m0/s1

Chave InChI: InChIKey=XUIIKFGFIJCVMT-LBPRGKRZSA-N

SMILES: O(C1=CC(I)=C(O)C(I)=C1)C2=C(I)C=C(C[C@@H](C(O)=O)N)C=C2I

Sinónimos:

• (-)-Thyroxine
• 3,3',5,5'-Tetraiodo-L-thyronine
• 3,3′,5,5′-Tetraiodo-<span class="text-smallcaps">L</span>-thyronine
• 3,5,3',5'-Tetraiodothyronine
• 3-[4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]-alanine
• <span class="text-smallcaps">L</span>-T₄
• <span class="text-smallcaps">L</span>-Thyroxin
• <span class="text-smallcaps">L</span>-Thyroxine
• <span class="text-smallcaps">L</span>-Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-
• Beta-[(3,5-Diiodo-4-Hydroxyphenoxy)-3,5-Diiodophenyl]Alanine
• DL-thyroxin
• DL-thyroxine
• DL-tiroxina
• Henning
• L-3,5,3',5'-Tetraiodothyronine
• L-T4
• L-Thyroxin
• L-Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-
• Levothyroxine
• Levotiron
• Nsc 36397
• O-(4-Hydroxy-3,5-Diiodophenyl)-3,5-Diiodo-L-Tyrosin
• O-(4-Hydroxy-3,5-Diiodophenyl)-3,5-Diiodotyrosine
• O-(4-Hydroxy-3,5-diiodophenyl)-3,5-diiodo-<span class="text-smallcaps">L</span>-tyrosine
• O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-L-tyrosine
• SK&amp;F 1-6528
• T4
• T4(Hormone)
• T₄
• T₄ (hormone)
• THX
• Tetraiodothyronine
• Thyrax
• Thyreoideum
• Thyroxin
• Thyroxinal
• Thyroxine, <span class="text-smallcaps">L</span>-

Levothyroxine

CAS: 51-48-9

Amino-acid derivatives

Fórmula: C₁₅H₁₁I₄NO₄

Cor e Forma: Yellow Off-White Crystalline Powder

Peso molecular: 776.6867

Ref: 45-1365000

L-Thyroxine Sodium Salt Pentahydrate

CAS: 51-48-9, 55-03-8, 6106-07-6

Fórmula: C₁₅H₁₀I₄NNaO₄·5H₂O

Pureza: >98.0%(T)

Cor e Forma: White to Yellow to Orange powder to crystal

Peso molecular: 888.94

Ref: 3B-T0245

L-Thyroxine, 98%

CAS: 51-48-9

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Fórmula: C₁₅H₁₁I₄NO₄

Pureza: 98%

Cor e Forma: Powder, Pale cream to cream

Peso molecular: 776.87

Ref: 02-J62606

Liothyronine EP Impurity A

CAS: 51-48-9

Fórmula: C₁₅H₁₁I₄NO₄

Peso molecular: 776.9

Ref: ST-EA-CP-L45001

L-Thyroxine-[l-tyr-ring-13c6] hydrochloride

CAS: 51-48-9

Fórmula: C₁₅H₁₁I₄NO₄

Pureza: 97%

Cor e Forma: Liquid

Peso molecular: 776.8700

Ref: IN-DA0038OW

L-Thyroxine

CAS: 51-48-9

L-Thyroxine, major thyroid hormone, is made by iodinating tyrosine and coupling it in thyroglobulin, then secreted into blood.

Fórmula: C₁₅H₁₁I₄NO₄

Pureza: 97.63% - 99.562%

Cor e Forma: Crystals Solid

Peso molecular: 776.87

Ref: TM-T0864

L-Thyroxine

CAS: 51-48-9

L-Thyroxine

Pureza: 97%

Peso molecular: 776.87g/mol

Ref: 54-OR1030066

L-Thyroxine

CAS: 51-48-9

Fórmula: C₁₅H₁₁I₄NO₄

Pureza: ≥ 98.0% (dried basis)

Cor e Forma: White to off-white crystalline powder

Peso molecular: 776.87

Ref: 7W-GP9966

L-Thyroxine (Tetraiodothyronine)

CAS: 51-48-9

Fórmula: C₁₅H₁₁I₄NO₄

Cor e Forma: White To Off-White Solid

Peso molecular: 776.87

Ref: 4Z-T-421

L-Thyroxine

CAS: 51-48-9

L-Thyroxine

Pureza: ≥95%

Peso molecular: 776.87g/mol

Ref: 54-BUP17744

L-Thyroxine

Produto Controlado

CAS: 51-48-9

Fórmula: C₁₅H₁₁I₄NO₄

Cor e Forma: Neat

Peso molecular: 776.87

Ref: 04-C17575300

Thyroxine (100% pure T4 reference standard (free of T3))

CAS: 51-48-9

Applications Thyroxine is one of the thyroid hormones involved in the maintenance of metabolic homeostasis. Synthesized and stored as amino acid residues of thyroglobulin, the major protein component of the thyroid follicular colloid. Synthesis and secretion are regulated by the pituitary hormone (TSH). Deiodinated in peripheral tissues to the active metabolite, liothyronine. The D-form has very little activity as a thyroid hormone, but has been used to treat hyperlipidemia.
References Post, A., et al.: Anal. Profiles Drug Subs., 5, 225 (1976); Nelson, J.C., et al.: Clin. Chem., 34, 1737 (1988); Fischer, D.A., et al.: Clin. Chem., 42, 135 (1996); Cavalieri, R.R., et al.: Thyroid, 7, 177 (1997);

Fórmula: C₁₅H₁₁I₄NO₄

Cor e Forma: Off-White

Peso molecular: 776.87

Ref: TR-T425650

Thyroxine

Produto Controlado

CAS: 51-48-9

Applications Thyroxine is one of the thyroid hormones involved in the maintenance of metabolic homeostasis. Synthesized and stored as amino acid residues of thyroglobulin, the major protein component of the thyroid follicular colloid. Synthesis and secretion are regulated by the pituitary hormone (TSH). Deiodinated in peripheral tissues to the active metabolite, liothyronine. The D-form has very little activity as a thyroid hormone, but has been used to treat hyperlipidemia.
References Post, A., et al.: Anal. Profiles Drug Subs., 5, 225 (1976); Nelson, J.C., et al.: Clin. Chem., 34, 1737 (1988); Fischer, D.A., et al.: Clin. Chem., 42, 135 (1996); Cavalieri, R.R., et al.: Thyroid, 7, 177 (1997);

Fórmula: C₁₅H₁₁I₄NO₄

Cor e Forma: Off-White

Peso molecular: 776.87

Ref: TR-T425600

Levothyroxine Lactose Adduct >85%

Produto Controlado

CAS: 51-48-9

Fórmula: C₂₇H₃₁I₄NO₁₄

Pureza: >85%

Cor e Forma: Neat

Peso molecular: 1101.151

Ref: TR-L378053

O-(4-HYDROXY-3,5-DIIODOPHENYL)-3,5-DIIODO-L-TYROSINE

CAS: 51-48-9

Pureza: 97%

Peso molecular: 776.8740234

Ref: 10-F837420

2-(3-(4-Hydroxy-3,5-diiodophenoxy)-2,4-diiodobenzamido)-3-(4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl)propanoic Acid, Amide-Bridged

Produto Controlado

CAS: 51-48-9

Fórmula: C₂₈H₁₆I₇NO₇

Cor e Forma: Neat

Peso molecular: 1366.76

Ref: TR-H972213

Levothyroxine

CAS: 51-48-9

Levothyroxine is a thyroid hormone that is used to treat hypothyroidism. It is taken in tablet form, usually once per day. Levothyroxine therapy can be started with a low dose and increased gradually over time. This drug has been shown to be effective in the treatment of bowel disease, which may be due to its ability to decrease inflammation and increase the movement of stool through the intestines. Levothyroxine has also been shown to have beneficial effects on other autoimmune diseases such as rheumatoid arthritis and congestive heart failure. The use of levothyroxine requires periodic blood sampling for monitoring.

Fórmula: C₁₅H₁₁I₄NO₄

Pureza: Min. 98 Area-%

Cor e Forma: Off-White Powder

Peso molecular: 776.87 g/mol

Ref: 3D-FL34087

L-Thyroxine-13C6

CAS: 51-48-9

Fórmula: C₉₁₃C₆H₁₁I₄NO₄

Peso molecular: 782.83

Ref: 4Z-T-422