CAS 51-48-9

(-)-Tiroxina

Descrição:

(-)-Tiroxina, também conhecido como L-tiroxina ou T4, é um hormônio produzido pela glândula tireoide que desempenha um papel crucial na regulação do metabolismo, crescimento e desenvolvimento no corpo. É um derivado tetraiodado do aminoácido tirosina, caracterizado pela presença de quatro átomos de iodo em sua estrutura. A fórmula química de (-)-Tiroxina é C15H11I4N0, e tem um peso molecular de aproximadamente 776,87 g/mol. Este composto é tipicamente encontrado como um pó cristalino branco a off-white e é solúvel em água e álcool, mas menos solúvel em solventes orgânicos. (-)-Tiroxina funciona ligando-se aos receptores de hormônios tireoidianos, influenciando a expressão gênica e os processos metabólicos. É comumente usado em ambientes clínicos para tratar o hipotireoidismo e outros distúrbios relacionados à tireoide. Sua atividade é monitorada de perto, pois tanto a deficiência quanto o excesso podem levar a problemas de saúde significativos. O número CAS 51-48-9 identifica exclusivamente este composto em bancos de dados químicos, facilitando a pesquisa e a conformidade regulatória.

Fórmula: C₁₅H₁₁I₄NO₄

InChI: InChI=1S/C15H11I4NO4/c16-8-4-7(5-9(17)13(8)21)24-14-10(18)1-6(2-11(14)19)3-12(20)15(22)23/h1-2,4-5,12,21H,3,20H2,(H,22,23)/t12-/m0/s1

Chave InChI: InChIKey=XUIIKFGFIJCVMT-LBPRGKRZSA-N

SMILES: O(C1=CC(I)=C(O)C(I)=C1)C2=C(I)C=C(C[C@@H](C(O)=O)N)C=C2I

Sinónimos:

• (-)-Thyroxine
• 3,3',5,5'-Tetraiodo-L-thyronine
• 3,3′,5,5′-Tetraiodo-<span class="text-smallcaps">L</span>-thyronine
• 3,5,3',5'-Tetraiodothyronine
• 3-[4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]-alanine
• <span class="text-smallcaps">L</span>-T₄
• <span class="text-smallcaps">L</span>-Thyroxin
• <span class="text-smallcaps">L</span>-Thyroxine
• <span class="text-smallcaps">L</span>-Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-
• Beta-[(3,5-Diiodo-4-Hydroxyphenoxy)-3,5-Diiodophenyl]Alanine
• DL-thyroxin
• DL-thyroxine
• DL-tiroxina
• Henning
• L-3,5,3',5'-Tetraiodothyronine
• L-T4
• L-Thyroxin
• L-Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-
• Levothyroxine
• Levotiron
• Nsc 36397
• O-(4-Hydroxy-3,5-Diiodophenyl)-3,5-Diiodo-L-Tyrosin
• O-(4-Hydroxy-3,5-Diiodophenyl)-3,5-Diiodotyrosine
• O-(4-Hydroxy-3,5-diiodophenyl)-3,5-diiodo-<span class="text-smallcaps">L</span>-tyrosine
• O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-L-tyrosine
• SK&amp;F 1-6528
• T4
• T4(Hormone)
• T₄
• T₄ (hormone)
• THX
• Tetraiodothyronine
• Thyrax
• Thyreoideum
• Thyroxin
• Thyroxinal
• Thyroxine, <span class="text-smallcaps">L</span>-

Levothyroxine

CAS: 51-48-9

Amino-acid derivatives

Fórmula: C₁₅H₁₁I₄NO₄

Cor e Forma: Yellow Off-White Crystalline Powder

Peso molecular: 776.6867

Ref: 45-1365000

L-Thyroxine, 98%

CAS: 51-48-9

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Fórmula: C₁₅H₁₁I₄NO₄

Pureza: 98%

Cor e Forma: Powder, Pale cream to cream

Peso molecular: 776.87

Ref: 02-J62606

LIOTHYRONINE FOR PEAK IDENTIFICATION CRS

CAS: 1041-01-6, 300-39-0, 51-24-1, 51-48-9, 67-30-1

LIOTHYRONINE FOR PEAK IDENTIFICATION CRS

Fórmula: C₁₅H₁₁I₃NNaO₄

Cor e Forma: Added

Peso molecular: 672.9553

Ref: 41-Y0000860

L-Thyroxine

CAS: 51-48-9

L-Thyroxine

Fórmula: C₁₅H₁₁I₄NO₄

Pureza: ≥95%

Peso molecular: 776.87

Ref: 54-BUP17744

L-Thyroxine

CAS: 51-48-9

L-Thyroxine, major thyroid hormone, is made by iodinating tyrosine and coupling it in thyroglobulin, then secreted into blood.

Fórmula: C₁₅H₁₁I₄NO₄

Pureza: 97.63% - 99.56%

Cor e Forma: Crystals Solid

Peso molecular: 776.87

Ref: TM-T0864

L-Thyroxine

CAS: 51-48-9

L-Thyroxine

Fórmula: C₁₅H₁₁I₄NO₄

Pureza: >97%

Cor e Forma: Solid

Peso molecular: 776.87

Ref: 54-OR1030066

O-(4-Hydroxy-3,5-diiodophenyl)-3,5-diiodo-L-tyrosine

CAS: 51-48-9

Fórmula: C₁₅H₁₁I₄NO₄

Pureza: 97%

Cor e Forma: Liquid

Peso molecular: 776.8700

Ref: IN-DA0038OW

L-Thyroxine

CAS: 51-48-9

Fórmula: C₁₅H₁₁I₄NO₄

Pureza: ≥ 98.0% (dried basis)

Cor e Forma: White to off-white crystalline powder

Peso molecular: 776.87

Ref: 7W-GP9966

L-Thyroxine (Liothyronine EP Impurity A, Levothyroxine, Tetraiodothyronine)

CAS: 51-48-9

Fórmula: C₁₅H₁₁I₄NO₄

Cor e Forma: White To Off-White Solid

Peso molecular: 776.87

Ref: 4Z-T-421

L-Thyroxine

Produto Controlado

CAS: 51-48-9

Fórmula: C₁₅H₁₁I₄NO₄

Cor e Forma: Neat

Peso molecular: 776.87

Ref: 04-C17575300

L-Thyroxine (Standard)

CAS: 51-48-9

L-Thyroxine (Standard) is the standard substance of L-Thyroxine, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. L-Thyroxine (NSC 36397) is the major hormone derived from the thyroid gland. L-Thyroxine (NSC 36397) is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. L-Thyroxine (NSC 36397) is released from thyroglobulin by proteolysis and secreted into the blood. L-Thyroxine (NSC 36397) is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.

Fórmula: C₁₅H₁₁I₄NO₄

Cor e Forma: Solid

Peso molecular: 776.87

Ref: TM-TMSM-1492

Levothyroxine Lactose Adduct >85%

Produto Controlado

CAS: 51-48-9

Fórmula: C₂₇H₃₁I₄NO₁₄

Pureza: >85%

Cor e Forma: Neat

Peso molecular: 1101.151

Ref: TR-L378053

Thyroxine (100% pure T4 reference standard (free of T3))

CAS: 51-48-9

Applications Thyroxine is one of the thyroid hormones involved in the maintenance of metabolic homeostasis. Synthesized and stored as amino acid residues of thyroglobulin, the major protein component of the thyroid follicular colloid. Synthesis and secretion are regulated by the pituitary hormone (TSH). Deiodinated in peripheral tissues to the active metabolite, liothyronine. The D-form has very little activity as a thyroid hormone, but has been used to treat hyperlipidemia.
References Post, A., et al.: Anal. Profiles Drug Subs., 5, 225 (1976); Nelson, J.C., et al.: Clin. Chem., 34, 1737 (1988); Fischer, D.A., et al.: Clin. Chem., 42, 135 (1996); Cavalieri, R.R., et al.: Thyroid, 7, 177 (1997);

Fórmula: C₁₅H₁₁I₄NO₄

Cor e Forma: Neat

Peso molecular: 776.87

Ref: TR-T425650

Thyroxine

Produto Controlado

CAS: 51-48-9

Applications Thyroxine is one of the thyroid hormones involved in the maintenance of metabolic homeostasis. Synthesized and stored as amino acid residues of thyroglobulin, the major protein component of the thyroid follicular colloid. Synthesis and secretion are regulated by the pituitary hormone (TSH). Deiodinated in peripheral tissues to the active metabolite, liothyronine. The D-form has very little activity as a thyroid hormone, but has been used to treat hyperlipidemia.
References Post, A., et al.: Anal. Profiles Drug Subs., 5, 225 (1976); Nelson, J.C., et al.: Clin. Chem., 34, 1737 (1988); Fischer, D.A., et al.: Clin. Chem., 42, 135 (1996); Cavalieri, R.R., et al.: Thyroid, 7, 177 (1997);

Fórmula: C₁₅H₁₁I₄NO₄

Cor e Forma: Neat

Peso molecular: 776.87

Ref: TR-T425600

Levothyroxine

CAS: 51-48-9

Fórmula: C₁₅H₁₁I₄NO₄

Peso molecular: 776.87

Ref: ST-EA-CP-L18000

Liothyronine EP Impurity A

CAS: 51-48-9

Fórmula: C₁₅H₁₁I₄NO₄

Peso molecular: 776.9

Ref: ST-EA-CP-L45001

L-Thyroxine

CAS: 51-48-9

Fórmula: C₁₅H₁₁I₄NO₄

Cor e Forma: Solid

Peso molecular: 776.87

Ref: BE-BePure-26042

L-Thyroxine

CAS: 51-48-9

Fórmula: C₁₅H₁₁I₄NO₄

Cor e Forma: Solid

Peso molecular: 776.87

Ref: BE-MU-2445

L-Thyroxine

CAS: 51-48-9

Fórmula: C₁₅H₁₁I₄NO₄

Cor e Forma: Solid

Peso molecular: 776.87

Ref: BE-RMCT176001

L-Thyroxine-[13C6] Hydrochloride(T4)

CAS: 51-48-9

Fórmula: C₁₅H₁₁I₄NO₄

Cor e Forma: Solid

Peso molecular: 776.87

Ref: BE-MC-2535C6