CAS 51166-71-3

Di-O-metil-β-ciclodextrina

Descrição:

Di-O-metil-β-ciclodextrina é um derivado modificado da β-ciclodextrina, que é um oligossacarídeo cíclico composto por sete unidades de glicose. Este composto apresenta dois grupos metóxi ligados às posições hidroxila das unidades de glicose, aumentando sua solubilidade em solventes orgânicos e melhorando sua capacidade de formar complexos de inclusão com várias moléculas hóspedes. Di-O-metil-β-ciclodextrina exibe características como maior lipofilicidade em comparação com a β-ciclodextrina nativa, tornando-o útil em aplicações farmacêuticas para entrega e estabilização de medicamentos. Possui um perfil de toxicidade relativamente baixo e é geralmente reconhecido como seguro para uso em formulações alimentares e farmacêuticas. A capacidade do composto de encapsular compostos hidrofóbicos permite uma melhor biodisponibilidade e liberação controlada de ingredientes ativos. Além disso, pode melhorar a estabilidade de compostos sensíveis contra degradação. Suas aplicações se estendem a áreas como cosméticos, ciência dos alimentos e remediação ambiental, onde pode ajudar na solubilização e entrega de várias substâncias.

Fórmula: C₅₆H₉₈O₃₅

InChI: InChI=1S/C56H98O35/c1-64-15-22-36-29(57)43(71-8)50(78-22)86-37-23(16-65-2)80-52(45(73-10)30(37)58)88-39-25(18-67-4)82-54(47(75-12)32(39)60)90-41-27(20-69-6)84-56(49(77-14)34(41)62)91-42-28(21-70-7)83-55(48(76-13)35(42)63)89-40-26(19-68-5)81-53(46(74-11)33(40)61)87-38-24(17-66-3)79-51(85-36)44(72-9)31(38)59/h22-63H,15-21H2,1-14H3/t22-,23-,24-,25-,26-,27-,28-,29+,30+,31+,32+,33+,34+,35+,36-,37-,38-,39-,40-,41-,42-,43-,44-,45-,46-,47-,48-,49-,50-,51-,52-,53-,54-,55-,56-/m1/s1

Chave InChI: InChIKey=QGKBSGBYSPTPKJ-UZMKXNTCSA-N

SMILES: C(OC)[C@@H]1[C@@]2([C@H](O)[C@@H](OC)[C@](O1)(O[C@@]3([C@@H](COC)O[C@@]([C@H](OC)[C@H]3O)(O[C@@]4([C@@H](COC)O[C@@]([C@H](OC)[C@H]4O)(O[C@@]5([C@@H](COC)O[C@](O[C@]6([C@H](O)[C@@H](OC)[C@@](O[C@]7([C@H](O)[C@@H](OC)[C@@](O[C@]8([C@H](O)[C@@H](OC)[C@@](O2)(O[C@@H]8COC)[H])[H])(O[C@@H]7COC)[H])[H])(O[C@@H]6COC)[H])[H])([C@H](OC)[C@H]5O)[H])[H])[H])[H])[H])[H])[H])[H]

Sinónimos:

• 2,4,7,9,12,14,17,19,22,24,27,29,32,34-Tetradecaoxaoctacyclo[31.2.2.2^3,6.2^8,11.2^13,16.2^18,21.2^23,26.2^28,31]nonatetracontane, β-cyclodextrin deriv.
• 2,6-2-Methyl-Beta-Cyclodextrin
• 2,6-Di-O-Methyl-Beta-Cyclodextrin
• 2,6-Di-O-methyl-β-cyclodextrin
• 2,6-Dimethyl-β-cyclodextrin
• 2^A,2^B,2^C,2^D,2^E,2^F,2^G,6^A,6^B,6^C,6^D,6^E,6^F,6^G-Tetradeca-O-methyl-β-cyclodextrin
• 2^A,6^A-Di-O-methyl-β-cyclodextrin
• Beta W 7M1.8
• Di-O-methyl-β-cyclodextrin
• Dimeb
• Dimeb 50
• Dimethyl-β-cyclodextrin
• Hepta-(2,6-di-oxy-methyl)-β-cyclodextrin
• Heptakis(2,6-di-O-methyl)-β-cyclodextrin
• Tetradeca-O-methyl-β-cyclodextrin
• Tetradecakis-2,6-O-methylcycloheptaamylose
• β-Cyclodextrin, 2^A,2^B,2^C,2^D,2^E,2^F,2^G,6^A,6^B,6^C,6^D,6^E,6^F,6^G-tetradeca-O-methyl-
• β-Cyclodextrin, 2A,2B,2C,2D,2E,2F,2G,6A,6B,6C,6D,6E,6F,6G-tetradeca-O-methyl-
• 2A,2B,2C,2D,2E,2F,2G,6A,6B,6C,6D,6E,6F,6G-Tetradeca-O-methyl-β-cyclodextrin

2,6-Di-O-methyl-beta-cyclodextrin

CAS: 51166-71-3

Fórmula: C₅₆H₉₈O₃₅

Pureza: >95.0%(HPLC)

Cor e Forma: White to Light yellow powder to crystal

Peso molecular: 1,331.37

Ref: 3B-D5992

Heptakis(2,6-di-O-methyl)-β-cyclodextrin content > 35% (DS~14)

CAS: 51166-71-3

Heptakis(2,6-di-O-methyl)-β-cyclodextrin content > 35% (DS~14)

Fórmula: C₅₆H₉₈O₃₅

Pureza: 95%

Cor e Forma: Solid-Powder

Peso molecular: 1331.35631

Ref: 54-BICY1000

Heptakis(2,6-di-O-methyl)-b-cyclodextrin

CAS: 51166-71-3

Fórmula: C₅₆H₉₈O₃₅

Pureza: ≥ 98% (2,6-Di-O-methyl-b-CD + other methyl CDs)

Cor e Forma: White to off-white powder

Peso molecular: 1331.36

Ref: 7W-GC9584

β-Cyclodextrin, 2A,2B,2C,2D,2E,2F,2G,6A,6B,6C,6D,6E,6F,6G-tetradeca-O-methyl-

CAS: 51166-71-3

Fórmula: C₅₆H₉₈O₃₅

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 1331.3563

Ref: IN-DA00I95Q

DM-β-CD

CAS: 51166-71-3

DM-β-CD (2,6-Di-O-methyl-β-cyclodextrin) is a cyclic molecule composed of seven glucose units, modified with two methyl groups at the 2 and 6 positions. It is commonly utilized as a solubilizer and carrier for poorly soluble drugs in pharmaceutical formulations. Additionally, its ability to form inclusion complexes with various guest molecules—such as aromatic compounds, pesticides, and heavy metals—makes it valuable in analytical chemistry, food science, and environmental remediation.

Fórmula: C₅₆H₉₈O₃₅

Peso molecular: 1331.3563

Ref: TM-TSH-00009

Di-O-methyl-b-cyclodextrin (90%)

Produto Controlado

CAS: 51166-71-3

Applications Induces the release of cholesterol from cholesterol-rich lipid rafts located on the surface of cells, making it a good agent for removing cholesterol from processed foods
References Krajian, H., et al.: Anal. Bioanal. Chem., 394, 2193 (2009), Perez-Cruz, F., et al.: Bioorg. Med. Chem., 17, 4604 (2009), Motoyama, K., et al.: Biol. Pharm. Bull., 32, 700 (2009), Padula, C., et al.: Int. J. Pharm., 372, 12 (2009), Chen, Z., et al.: J. Pharm. Sci., 98, 229 (2009),

Fórmula: C₅₆H₉₈O₃₅

Pureza: 90%

Cor e Forma: Neat

Peso molecular: 1331.36

Ref: TR-D470870

2,6-Dimethyl-b-cyclodextrin - Technical

CAS: 51166-71-3

This beta-cyclodextrin (β-CD) derivative is a functionalized cyclic oligosaccharide composed of seven glucose units, characterized by a hydrophilic exterior and a lipophilic cavity (bigger than α-CD and smaller than γ-CDs), which allows it to encapsulate various guest molecules. This structural feature facilitates its use in multiple applications, including pharmaceuticals, food enhancement, and cosmetics. In the pharmaceutical industry, it enhances the solubility and stability of poorly water-soluble drugs, improving their bioavailability and efficacy while also masking unpleasant tastes. The food sector utilizes it as a stabilizer for flavors, colors, and nutrients, extending shelf life by protecting sensitive ingredients from degradation. In cosmetics, it serves as a complexing agent for fragrances and active components, ensuring their stability and controlled release. Its use expands to many other fields, including nanotechnology for drug delivery systems, environmental remediation for extracting organic pollutants, textiles for slow-release fragrances, and analytical chemistry for chiral separation.

Fórmula: C₅₆H₉₈O₃₅

Pureza: Min. 98%

Cor e Forma: White Powder

Peso molecular: 1,331.36 g/mol

Ref: 3D-OD08100

2,6-Dimethyl-beta-cyclodextrin

CAS: 51166-71-3

This beta-cyclodextrin (β-CD) derivative is a functionalized cyclic oligosaccharide composed of seven glucose units, characterized by a hydrophilic exterior and a lipophilic cavity (bigger than α-CD and smaller than γ-CDs), which allows it to encapsulate various guest molecules. This structural feature facilitates its use in multiple applications, including pharmaceuticals, food enhancement, and cosmetics. In the pharmaceutical industry, it enhances the solubility and stability of poorly water-soluble drugs, improving their bioavailability and efficacy while also masking unpleasant tastes. The food sector utilizes it as a stabilizer for flavors, colors, and nutrients, extending shelf life by protecting sensitive ingredients from degradation. In cosmetics, it serves as a complexing agent for fragrances and active components, ensuring their stability and controlled release. Its use expands to many other fields, including nanotechnology for drug delivery systems, environmental remediation for extracting organic pollutants, textiles for slow-release fragrances, and analytical chemistry for chiral separation.

Fórmula: C₅₆H₉₈O₃₅

Pureza: Min. 98%

Cor e Forma: White Powder

Peso molecular: 1,331.36 g/mol

Ref: 3D-OD29274

2,6-Di-O-methyl-β-cyclodextrin

CAS: 51166-71-3

2,6-Di-O-methyl-β-cyclodextrin

Fórmula: C₅₆H₉₈O₃₅

Pureza: 98%

Peso molecular: 1331.36

Ref: IN-DG297838

2,6-DI-O-METHYL-β-CYCLODEXTRIN

CAS: 51166-71-3

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 1331.36499

Ref: 10-F813397