CAS 522-51-0

Cloreto de dequalínio

Descrição:

Cloreto de dequalínio é um composto de amônio quaternário caracterizado por suas propriedades antimicrobianas de amplo espectro. Aparece como um pó cristalino branco a off-white e é solúvel em água, tornando-o adequado para várias aplicações, particularmente em produtos farmacêuticos e de cuidados pessoais. O composto é conhecido por sua eficácia contra uma variedade de bactérias e fungos, o que o torna valioso em formulações antissépticas e como conservante. Cloreto de dequalínio funciona ao interromper as membranas celulares microbianas, levando à morte celular. É frequentemente utilizado em pastilhas para a garganta, enxaguantes bucais e antissépticos tópicos. Além disso, foi investigado para uso potencial no tratamento de infecções e como desinfetante. Embora geralmente seja considerado seguro quando usado conforme as instruções, pode causar irritação em alguns indivíduos, particularmente em áreas sensíveis. Assim como com qualquer substância química, o manuseio adequado e a adesão às diretrizes de segurança são essenciais para minimizar os riscos associados à exposição.

Fórmula: C₃₀H₄₀N₄·2Cl

InChI: InChI=1S/C30H38N4.2ClH/c1-23-21-27(31)25-15-9-11-17-29(25)33(23)19-13-7-5-3-4-6-8-14-20-34-24(2)22-28(32)26-16-10-12-18-30(26)34;;/h9-12,15-18,21-22,31-32H,3-8,13-14,19-20H2,1-2H3;2*1H

Chave InChI: InChIKey=LTNZEXKYNRNOGT-UHFFFAOYSA-N

SMILES: C(CCCCCCCCC[N+]=1C2=C(C(N)=CC1C)C=CC=C2)[N+]=3C4=C(C(N)=CC3C)C=CC=C4.[Cl-]

Sinónimos:

• 1,1'-Decane-1,10-Diylbis(4-Amino-2-Methylquinolinium) Dichloride
• 1,1′-Decamethylenebis[4-aminoquinaldinium chloride]
• Badq 10
• Baqd 10
• Decamethylenebis[4-aminoquinaldinium chloride]
• Decamine
• Decamine (pharmaceutical)
• Decatylen
• Dekadin
• Dekamiln
• Dekamin
• Dequacets
• Dequadin
• Dequadin chloride
• Dequafungen
• Dequalinum Chloride
• Dequavagyn
• Dequavet
• Efisol
• Eriosept
• Evazol
• Fluomizin
• Fluomycin N
• Grocreme
• Ivazil
• Labosept
• Ldn 0096422
• NSC 166454
• Optipect
• Oralgol
• Phylletten
• Polycidine
• Quinaldinium, 1,1′-decamethylenebis[4-amino-, dichloride
• Quinolinium, 1,1′-(1,10-decanediyl)bis[4-amino-2-methyl-, chloride (1:2)
• Quinolinium, 1,1′-(1,10-decanediyl)bis[4-amino-2-methyl-, dichloride
• Rumilet
• Sanoral
• Sentril

DEQUALINIUM CHLORIDE FOR ID CRS

CAS: 522-51-0

DEQUALINIUM CHLORIDE FOR ID CRS

Ref: 41-Y0002332

DEQUALINIUM FOR SYSTEM SUITABILITY CRS

CAS: 522-51-0

DEQUALINIUM FOR SYSTEM SUITABILITY CRS

Ref: 41-Y0002333

Dequalinium Chloride

CAS: 522-51-0

Fórmula: C₃₀H₄₀Cl₂N₄

Pureza: 99%

Cor e Forma: Solid

Peso molecular: 527.5714

Ref: IN-DA019FVH

Dequalinium chloride

CAS: 522-51-0

Dequalinium chloride: topical bacteriostat, blocks apamin-sensitive K+ channels, used for wounds, oral infections, potential antifungal, risk of skin ulcers.

Fórmula: C₃₀H₄₀Cl₂N₄

Pureza: 99.79% - 99.9%

Cor e Forma: Solid

Peso molecular: 527.59

Ref: TM-T0979

1,1'-(Decane-1,10-Diyl)Bis(4-Amino-2-Methylquinolin-1-Ium) Chloride

CAS: 522-51-0

1,1'-(Decane-1,10-Diyl)Bis(4-Amino-2-Methylquinolin-1-Ium) Chloride

Pureza: 98%

Peso molecular: 527.57g/mol

Ref: 54-OR1026217

Dequalinium chloride

CAS: 522-51-0

Dequalinium chloride

Pureza: ≥98%

Peso molecular: 527.59g/mol

Ref: 54-BUP14027

Dequalinium Dichloride

CAS: 522-51-0

Fórmula: C₃₀H₄₀N₄·2Cl

Cor e Forma: Off-White Solid

Peso molecular: 456.68 2*35.45

Ref: 4Z-D-084004

Dequalinium Chloride

CAS: 522-51-0

Fórmula: C₃₀H₄₀N₄Cl

Cor e Forma: Neat

Peso molecular: 527.57

Ref: 86-MM1705.00

Dequalinium chloride

CAS: 522-51-0

Fórmula: C₃₀H₄₀Cl₂N₄·xH₂O

Pureza: 95.0 - 101.0 % (dried basis)

Cor e Forma: White, off-white or light yellow powder

Peso molecular: 527.57 (anhydrous)

Ref: 7W-GE7850

Dequalinium-d8 DiChloride

CAS: 522-51-0

Fórmula: C₃₀H₃₂D₈N₄·2Cl

Peso molecular: 464.73 2*35.45

Ref: 4Z-D-084010

Dequalinium chloride

CAS: 522-51-0

Dequalinium chloride is a quaternary ammonium compound that has been discovered to be an inhibitor of the cytopathic effects of some syndrome viruses. It is able to inhibit the replication of the virus in various clinical isolates and in cell culture models. Dequalinium chloride also inhibits acetylcholine receptor-mediated endocytosis, which is one of the mechanisms by which cells resist infection. The mechanism by which dequalinium chloride inhibits acetylcholine receptor-mediated endocytosis is not yet known, but it has been suggested that it might be due to its inhibitory activity on mitochondrial uncoupler proteins. This property may make dequalinium chloride an effective treatment against bacterial infections and respiratory diseases such as cystic fibrosis and asthma.

Fórmula: C₃₀H₄₀Cl₂N₄

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 527.57 g/mol

Ref: 3D-FD40542

Dequalinium chloride

CAS: 522-51-0

Pureza: 99%

Peso molecular: 526.263

Ref: 10-F797293

Dequalinium chloride

CAS: 522-51-0

Dequalinium chloride is a novel, broad spectrum antimicrobial agent with a mechanism of action that inhibits the mitochondria-dependent respiratory chain. Studies have shown that it inhibits the growth of resistant microorganisms in cell-based experiments and in bacterial infections. Dequalinium chloride also has cytopathic effects on thp-1 cells, which are specific for Mycobacterium tuberculosis. In addition to inhibiting mitochondria-dependent respiration, this compound also increases acetylcholine receptor sensitivity in A549 lung cancer cells. Dequalinium chloride is a quaternary ammonium cation and has been shown to be effective against clinical isolates and inhibitory concentrations of a variety of virus species, including human rhinovirus (HRV) and Coxsackie virus type B4 (CoxB4).

Fórmula: C₃₀H₄₀Cl₂N₄

Pureza: Min. 95.0 Area-%

Peso molecular: 527.57 g/mol

Ref: 3D-W-105841

Dequalinium Chloride

CAS: 522-51-0

Cor e Forma: Neat

Ref: 61-FOR1705.00