CAS 52214-84-3

Ciprofibrato

Descrição:

Ciprofibrato é um composto sintético classificado como um fibrato, utilizado principalmente no manejo da dislipidemia, particularmente para reduzir os níveis de triglicerídeos e aumentar o colesterol de lipoproteínas de alta densidade (HDL). Sua estrutura química apresenta um grupo fenoxi e um grupo ácido carboxílico, que contribuem para suas propriedades moduladoras de lipídios. A substância é conhecida por sua capacidade de ativar os receptores ativados por proliferadores de peroxissomos (PPARs), que desempenham um papel crucial no metabolismo lipídico. Ciprofibrato é tipicamente administrado por via oral e é bem absorvido no trato gastrointestinal. Apresenta uma meia-vida moderada, permitindo a dosagem uma ou duas vezes ao dia. O composto é geralmente bem tolerado, embora os efeitos colaterais potenciais possam incluir distúrbios gastrointestinais e problemas relacionados aos músculos. Assim como outros fibratos, é importante monitorar a função hepática e os níveis de enzimas musculares durante o tratamento. Ciprofibrato é frequentemente utilizado em conjunto com modificações no estilo de vida e outros agentes redutores de lipídios para alcançar resultados terapêuticos ideais em pacientes com níveis elevados de lipídios.

Fórmula: C₁₃H₁₄Cl₂O₃

InChI: InChI=1/C13H14Cl2O3/c1-12(2,11(16)17)18-9-5-3-8(4-6-9)10-7-13(10,14)15/h3-6,10H,7H2,1-2H3,(H,16,17)

Chave InChI: InChIKey=KPSRODZRAIWAKH-UHFFFAOYSA-N

SMILES: ClC1(Cl)C(C1)C2=CC=C(OC(C(O)=O)(C)C)C=C2

Sinónimos:

• 2-(4-(2,2-Dichlorocyclopropyl)phenoxy)2-methylpropanoic acid
• 2-(p-(2,2-Dichlorocyclopropyl)phenoxy)-2-methylpropionic acid
• 2-[4-(2,2-Dichloro-cyclopropyl)-phenoxy]-2-methyl-propionic acid
• Brn 1984981
• Ccris 173
• Ciprofibrato
• Ciprofibrato [INN-Spanish]
• Ciprofibratum
• Ciprofibratum [INN-Latin]
• Ciprol
• Lipanor
• Modalim
• Propanoic acid, 2-(4-(2,2-dichlorocyclopropyl)phenoxy)-2-methyl-
• Unii-F8252Jgo9S
• Win 35833
• Ciprofibrate
• 2-(p-(2,2-dichlorocyclopropyl)phenoxy)-2-methylpropionicacid
• Cipml
• 2-[4-(2，2-Dichlom-cyclopropyl)phenoxy]-2-methy|propanoic acid
• 2-(4-(2,2-dichlorocyclopropyl)phenoxy)-2-methyl-propionicaci
• Ciprofibric acid
• 2-(4-(2,2-dichlorocyclopropyl)phenoxy)-2-methyl-propanoicaci
• 2-[P-(2,2-DICHLOROCYCLOPROPYL)-PHENOXY]-2-METHYLPROPANOIC ACID

Ciprofibrate

CAS: 52214-84-3

Fórmula: C₁₃H₁₄Cl₂O₃

Pureza: >98.0%(GC)(T)

Cor e Forma: White to Light yellow powder to crystal

Peso molecular: 289.15

Ref: 3B-C2667

Ciprofibrate impurity standard

CAS: 52214-84-3

Ciprofibrate impurity standard

Cor e Forma: White

Ref: 47-1312

Ciprofibrate

CAS: 52214-84-3

Ciprofibrate

Fórmula: C₁₃H₁₄Cl₂O₃

Pureza: 99.9%

Cor e Forma: White

Peso molecular: 288.032

Ref: 47-1278

CIPROFIBRATE CRS

CAS: 52214-84-3

CIPROFIBRATE CRS

Fórmula: C₁₃H₁₄Cl₂O₃

Cor e Forma: Crystalline Powder. White. Whitish. Powder.

Peso molecular: 289.1545

Ref: 41-Y0000362

Propanoic acid, 2-[4-(2,2-dichlorocyclopropyl)phenoxy]-2-methyl-

CAS: 52214-84-3

Fórmula: C₁₃H₁₄Cl₂O₃

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 289.1545

Ref: IN-DA00I9CC

Ciprofibrate

CAS: 52214-84-3

Ciprofibrate

Fórmula: C₁₃H₁₄Cl₂O₃

Pureza: ≥98%

Peso molecular: 289.15

Ref: 54-BUP16708

2-(4-(2,2-Dichlorocyclopropyl)Phenoxy)-2-Methylpropanoic Acid

CAS: 52214-84-3

2-(4-(2,2-Dichlorocyclopropyl)Phenoxy)-2-Methylpropanoic Acid

Fórmula: C₁₃H₁₄Cl₂O₃

Pureza: 98%

Peso molecular: 289.15

Ref: 54-OR1009741

Ciprofibrate

CAS: 52214-84-3

Fórmula: C₁₃H₁₄Cl₂O₃

Pureza: ≥ 98.0%

Cor e Forma: White to light-yellow powder or crystals

Peso molecular: 289.15

Ref: 7W-GP0375

Ciprofibrate

CAS: 52214-84-3

Fórmula: C₁₃H₁₄Cl₂O₃

Cor e Forma: Off-White Solid

Peso molecular: 289.15

Ref: 4Z-C-681

Ciprofibrate

CAS: 52214-84-3

Cor e Forma: Neat

Ref: 61-FOR1141.00

Ciprofibrate

Produto Controlado

CAS: 52214-84-3

Fórmula: C₁₃H₁₄Cl₂O₃

Cor e Forma: Neat

Peso molecular: 289.15

Ref: 86-MM1141.00

Ciprofibrate

CAS: 52214-84-3

2-(4-(2,2-Dichlorocyclopropyl)phenoxy)-2-methylpropanoic acid

Fórmula: C₁₃H₁₄Cl₂O₃

Pureza: 98%

Peso molecular: 289.15

Ref: IN-DG121411

Ciprofibrate

CAS: 52214-84-3

Ciprofibrate (Win35833) is a fibrate derivative with antilipidemic activity.

Fórmula: C₁₃H₁₄Cl₂O₃

Pureza: 99.63% - >99.99%

Cor e Forma: White Or Almost White Crystalline Powder

Peso molecular: 289.15

Ref: TM-T1264

Ciprofibrate

Produto Controlado

CAS: 52214-84-3

Applications Ciprofibrate is a hypolipemic agent, related structurally to Clofibrate (C586910). Ciprofibrate is used as an antilipemic.
References Davison, C., et al.: Drug. Metab. Dispos., 3, 520 (1975), Arnold, A., et al.: J. Pharm. Sci., et al.: 68, 1557 (1979), Tuchman-Duplessis, H., et al.: Toxicology, 12, 1 (1979),

Fórmula: C₁₃H₁₄Cl₂O₃

Cor e Forma: Neat

Peso molecular: 289.15

Ref: TR-C482475

Ciprofibrate - Bio-X ™

CAS: 52214-84-3

Ciprofibrate is a fibrate drug that is used as a lipid-lowering agent. This drug reduces both LDL and VLDL cholesterol levels in the blood. Ciprofibrate works by reducing the production of triglycerides in the liver and increasing the removal of triglycerides from the blood. This drug is an agonist of peroxisome proliferator-activated receptor alpha.

Fórmula: C₁₃H₁₄Cl₂O₃

Pureza: Min. 98 Area-%

Cor e Forma: Powder

Peso molecular: 289.15 g/mol

Ref: 3D-BD164311

2-[4-(2,2-Dichlorocyclopropyl)phenoxy]-2-methylpropanoic acid

CAS: 52214-84-3

2-[4-(2,2-Dichlorocyclopropyl)phenoxy]-2-methylpropanoic acid (CGP) is a drug that blocks the nuclear receptor PPARγ. It has been shown to reduce cholesterol levels by inhibiting the synthesis of cholesterol, as well as reducing liver lesions in vivo. CGP also inhibits the growth of cancer cells through its ability to bind to DNA and regulate transcriptional activity. The response element for this compound is found in the promoter region of the gene encoding the growth factor-β1 (GF-β1), which is an important regulator of cell proliferation, differentiation, and apoptosis. CGP also inhibits peroxisome proliferator activator receptor α (PPARα) and γ (PPARγ). This inhibition leads to decreased expression of genes involved in lipid metabolism, such as acyl CoA synthase and fatty acid synthetase. CGP has also been shown to be carcinogenic in vivo

Fórmula: C₁₃H₁₄Cl₂O₃

Pureza: Min. 98 Area-%

Cor e Forma: Powder

Peso molecular: 289.15 g/mol

Ref: 3D-FD11320

2-(4-(2,2-Dichlorocyclopropyl)phenoxy)-2-methylpropanoic acid

CAS: 52214-84-3

Fórmula: C₁₃H₁₄Cl₂O₃

Pureza: 95.0%

Cor e Forma: Solid, White to slightly pale yellow powder

Peso molecular: 289.15

Ref: 10-F212903

Ciprofibrate

CAS: 52214-84-3

Fórmula: C₁₃H₁₄Cl₂O₃

Peso molecular: 289.15

Ref: ST-EA-CP-C77000