CAS 52286-59-6

Ginsenosídeo Re

Descrição:

Ginsenosídeo Re é um composto natural classificado como uma saponina triterpenoide, encontrado principalmente em espécies de ginseng, particularmente Panax ginseng. É conhecido por sua estrutura complexa, que inclui uma espinha dorsal semelhante a um esteroide com múltiplos grupos de açúcar anexados, contribuindo para sua bioatividade. Ginsenosídeo Re exibe várias propriedades farmacológicas, incluindo efeitos anti-inflamatórios, antioxidantes e neuroprotetores, tornando-se um assunto de interesse em química medicinal e farmacologia. Seu mecanismo de ação muitas vezes envolve a modulação de vias de sinalização, influenciando processos celulares como apoptose e proliferação. Além disso, Ginsenosídeo Re tem sido estudado por seus potenciais benefícios em melhorar a função cognitiva e apoiar a saúde cardiovascular. O composto é tipicamente extraído das raízes de ginseng e pode ser analisado usando técnicas como cromatografia líquida de alta eficiência (HPLC). Devido ao seu potencial terapêutico, Ginsenosídeo Re é frequentemente incluído em suplementos dietéticos e formulações herbais destinadas a promover a saúde e o bem-estar geral. No entanto, mais pesquisas são necessárias para elucidar completamente seus mecanismos e aplicações terapêuticas.

Fórmula: C₄₈H₈₂O₁₈

InChI: InChI=1S/C48H82O18/c1-21(2)11-10-14-48(9,66-42-38(60)35(57)32(54)26(19-49)63-42)23-12-16-46(7)30(23)24(51)17-28-45(6)15-13-29(52)44(4,5)40(45)25(18-47(28,46)8)62-43-39(36(58)33(55)27(20-50)64-43)65-41-37(59)34(56)31(53)22(3)61-41/h11,22-43,49-60H,10,12-20H2,1-9H3/t22-,23-,24+,25-,26+,27+,28+,29-,30-,31-,32+,33+,34+,35-,36-,37+,38+,39+,40-,41-,42-,43+,45+,46+,47+,48-/m0/s1

Chave InChI: InChIKey=PWAOOJDMFUQOKB-WCZZMFLVSA-N

SMILES: C[C@]12[C@@]([C@]3(C)[C@@]([C@@H](O[C@H]4[C@H](O[C@H]5[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O5)[C@@H](O)[C@H](O)[C@@H](CO)O4)C1)(C(C)(C)[C@@H](O)CC3)[H])(C[C@@H](O)[C@]6([C@@]2(C)CC[C@@]6([C@@](O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O)(CCC=C(C)C)C)[H])[H])[H]

Sinónimos:

• (3β,6α,12β)-20-(β-<span class="text-smallcaps">D</smallcap>-Glucopyranosyloxy)-3,12-dihydroxydammar-24-en-6-yl 2-O-(6-deoxy-α-<smallcap>L</smallcap>-mannopyranosyl)-β-<smallcap>D</span>-glucopyranoside
• 2-O-(6-Desoxy-α-L-mannopyranosyl)-(3β,6α,12β)-20-(β-D-glucopyranosyloxy)-3,12-dihydroxydammar-24-en-6-yl-β-D-glucopyranosid
• 2-O-(6-deoxy-α-L-mannopyranosyl)-(3β,6α,12β)-20-(β-D-glucopyranosyloxy)-3,12-dihydroxydammar-24-en-6-yl-β-D-glucopyranoside
• 2-O-(6-desoxi-α-L-manopiranosil)-(3β,6α,12β)-20-(β-D-glucopiranosiloxi)-3,12-dihidroxidamar-24-en-6-il-β-D-glucopiranosido
• 2-O-(6-desoxy-α-L-mannopyrannosyl)-(3β,6α,12β)-20-(β-D-glucopyrannosyloxy)-3,12-dihydroxydammar-24-ene-6-yl-β-D-glucopyrannoside
• Chikusetsusaponin IVc
• Ginsenoside B2
• Ginsenoside B₂
• Ginsenoside Re
• Notoginsenoside Re
• Nsc 308877
• Panaxoside Re
• Re ginsenoside
• Sanchinoside Re
• β-<span class="text-smallcaps">D</smallcap>-Glucopyranoside, (3β,6α,12β)-20-(β-<smallcap>D</smallcap>-glucopyranosyloxy)-3,12-dihydroxydammar-24-en-6-yl 2-O-(6-deoxy-α-<smallcap>L</span>-mannopyranosyl)-
• 2-O-(6-Deoxy-alpha-L-mannopyranosyl)-(3beta,6alpha,12beta)-20-(beta-D-glucopyranosyloxy)-3,12-dihydroxydammar-24-en-6-yl-beta-D-glucopyranoside
• (3β,6α,12β)-20-(β-D-Glucopyranosyloxy)-3,12-dihydroxydammar-24-en-6-yl 2-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranoside
• (3beta,6alpha,12beta)-20-(beta-D-glucopyranosyloxy)-3,12-dihydroxydammar-24-en-6-yl 2-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranoside
• Ginsenoside
• β-D-Glucopyranoside, (3β,6α,12β)-20-(β-D-glucopyranosyloxy)-3,12-dihydroxydammar-24-en-6-yl 2-O-(6-deoxy-α-L-mannopyranosyl)-
• (3beta,6alpha,9xi,12beta,13alpha)-20-[(3xi)-beta-D-ribo-hexopyranosyloxy]-3,12-dihydroxydammar-24-en-6-yl 2-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranoside

Ginsenoside Re

CAS: 52286-59-6

Ginsenoside Re analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Fórmula: C₄₈H₈₂O₁₈

Pureza: (HPLC) ≥98%

Cor e Forma: Powder

Peso molecular: 947.18

Ref: 11-0103S

Ginsenoside Re

CAS: 52286-59-6

Fórmula: C₄₈H₈₂O₁₈

Cor e Forma: White To Off-White Solid

Peso molecular: 947.17

Ref: 4Z-G-157014

Ginsenoside Re

CAS: 52286-59-6

Ginsenoside Re

Pureza: ≥98%

Peso molecular: 947.15g/mol

Ref: 54-BUP13312

Ginsenoside Re

CAS: 52286-59-6

Ginsenoside Re, a main phytosterol of Panax ginseng, inhibits Ca(2+) accumulation in mitochondria during cardiac ischemia/reperfusion, which is attributable to nitric oxide (NO)-induced Ca(2+) channel inhibition and K(+) channel activation in cardiac myocytes, acts as a specific agonist for the nongenomic pathway of sex steroid receptors, and NO released from activated eNOS underlies cardiac K(+) channel activation and protection against ischemia-reperfusion injury, G-Re also exerts antiischemic effect and induces angiogenic regeneration.[1,2]

Fórmula: C₄₈H₈₂O₁₈

Pureza: 95%~99%

Cor e Forma: White powder

Peso molecular: 947.166

Ref: BP-BP0662

Ginsenoside Re

CAS: 52286-59-6

Fórmula: C₄₈H₈₂O₁₈

Pureza: >95.0%(HPLC)(qNMR)

Cor e Forma: White to Light yellow powder to crystal

Peso molecular: 947.17

Ref: 3B-G0551

Ginsenoside Re

CAS: 52286-59-6

Ginsenoside Re (Ginsenoside B2) may have properties that inhibit or prevent the growth of tumors.

Fórmula: C₄₈H₈₂O₁₈

Pureza: 99.12% - >99.99%

Cor e Forma: White Powder

Peso molecular: 947.15

Ref: TM-T2872

Ginsenoside Re

CAS: 52286-59-6

Fórmula: C₄₈H₈₂O₁₈

Pureza: ≥ 98.0%

Cor e Forma: White to off-white powder

Peso molecular: 947.15

Ref: 7W-GC5949

Ginsenoside re

CAS: 52286-59-6

Natural glycoside

Fórmula: C₄₈H₈₂O₁₈

Pureza: ≥ 95.0 % (HPLC)

Cor e Forma: Powder

Peso molecular: 947.17

Ref: 5G-89212

Ginsenoside Re

CAS: 52286-59-6

Applications Ginsenoside Re is an extract from ginger, responsible for some of the pharmacological functions. It displays cardiac contractility, anti-ischemic and anti-arrythmic activities.
References Peng, D. et al.: Chinese Med., 7, 2 (2012); Endale, M. et al.: Med. Inflamm., 748964/1 (2014);

Fórmula: C₄₈H₈₂O₁₈

Cor e Forma: Neat

Peso molecular: 947.15

Ref: TR-G388000

Ginsenoside Re

CAS: 52286-59-6

Ginsenoside Re is a naturally occurring saponin, which is a bioactive compound sourced primarily from the root of Panax ginseng. It operates through multiple biochemical pathways, including the modulation of immune responses, anti-inflammatory effects, and protective antioxidant activities. Ginsenoside Re exerts its actions by interacting with cellular receptors, influencing signaling pathways such as the PI3K/Akt and MAPK pathways, ultimately impacting gene expression and cellular responses.

Fórmula: C₄₈H₈₂O₁₈

Pureza: Min. 98 Area-%

Cor e Forma: White Powder

Peso molecular: 947.18 g/mol

Ref: 3D-OG09285

Ginsenoside Re

CAS: 52286-59-6

Fórmula: C₄₈H₈₂O₁₈

Peso molecular: 947.17

Ref: ST-EA-CP-G62008