CAS 524-17-4

Dauricina

Descrição:

Dauricina, com o número CAS 524-17-4, é um alcaloide derivado de várias espécies de plantas, particularmente aquelas da família Menispermaceae. É conhecido por sua complexidade estrutural, apresentando uma estrutura tetracíclica que contribui para sua atividade biológica. Dauricina exibe uma variedade de propriedades farmacológicas, incluindo efeitos analgésicos, anti-inflamatórios e potenciais antitumorais, tornando-o de interesse na química medicinal. O composto é tipicamente encontrado na forma de um sólido cristalino branco a amarelo pálido e é solúvel em solventes orgânicos como etanol e clorofórmio, mas menos solúvel em água. Acredita-se que seu mecanismo de ação envolva a modulação de sistemas de neurotransmissores e a interferência com vias de sinalização celular. Devido à sua natureza bioativa, a pesquisa continua sobre seu potencial terapêutico e perfil de segurança, embora mais estudos sejam necessários para entender completamente sua eficácia e mecanismos em vários contextos biológicos. Assim como muitos alcaloides, é aconselhável ter cautela em relação ao seu uso, pois pode apresentar toxicidade em concentrações mais altas.

Fórmula: C₃₈H₄₄N₂O₆

InChI: InChI=1/C38H44N2O6/c1-39-15-13-26-20-35(42-3)37(44-5)22-29(26)31(39)17-24-7-10-28(11-8-24)46-34-19-25(9-12-33(34)41)18-32-30-23-38(45-6)36(43-4)21-27(30)14-16-40(32)2/h7-12,19-23,31-32,41H,13-18H2,1-6H3

Chave InChI: InChIKey=AQASRZOCERRGBL-ROJLCIKYSA-N

SMILES: C([C@@H]1C=2C(=CC(OC)=C(OC)C2)CCN1C)C3=CC(OC4=CC=C(C[C@@H]5C=6C(=CC(OC)=C(OC)C6)CCN5C)C=C4)=C(O)C=C3

Sinónimos:

• 4-[(6,7-Dimethoxy-2-Methyl-1,2,3,4-Tetrahydroisoquinolin-1-Yl)Methyl]-2-{4-[(6,7-Dimethoxy-2-Methyl-1,2,3,4-Tetrahydroisoquinolin-1-Yl)Methyl]Phenoxy}Phenol
• 4-[[(1R)-1,2,3,4-Tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl]methyl]-2-[4-[[(1R)-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl]methyl]phenoxy]phenol
• 4-{[(1R)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-1-yl]methyl}-2-(4-{[(1R)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-1-yl]methyl}phenoxy)phenol
• Nsc 36413
• Phenol, 4-((1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl)methyl)-2-(4-((1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl)methyl)phenoxy)-, (R-(R*,R*))-
• Phenol, 4-[[(1R)-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl]methyl]-2-[4-[[(1R)-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl]methyl]phenoxy]-
• Dauricine
• 6,6'-Di-O-Methyldauricoline
• Menispermum dauricum DC Extract
• (r-(r*,r*))-y)
• -(4-((1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl)methyl)phenox
• dauricine (8ci)

Dauricine

CAS: 524-17-4

Fórmula: C₃₈H₄₄N₂O₆

Peso molecular: 624.77

Ref: 7W-GP0181

Dauricine

CAS: 524-17-4

Dauricine

Fórmula: C₃₈H₄₄N₂O₆

Pureza: 99.5%

Peso molecular: 624.77

Ref: 54-BUP07831

Dauricine

CAS: 524-17-4

Fórmula: C₃₈H₄₄N₂O₆

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 624.7658

Ref: IN-DA00DEJ0

Dauricine

CAS: 524-17-4

Fórmula: C₃₈H₄₄N₂O₆

Pureza: 95%~99%

Peso molecular: 624.778

Ref: BP-BP0452

Dauricine (Standard)

CAS: 524-17-4

Dauricine (Standard) is a reference standard for research and analysis in studies involving Dauricine. 1. Dauricine has pulmonary toxicity, can produce pulmonary injury in CD-1 mice by the metabolism of Dauricine mediated by CYP3A. 2. Dauricinec can pass the blood-brain barrier, and that P-glycoprotein has an important role in the transportation of Dauricine across the blood-brain barrier. 3. Dauricine may has anti-tumor effect, can inhibit tumor cells in urinary system and colon cancer cell proliferation, invasion; induce cell apoptosis by suppressing NF-kappaB activity and the expression profile of its downstream genes.

Fórmula: C₃₈H₄₄N₂O₆

Peso molecular: 624.7658

Ref: TM-TMSM-0845

Dauricine

Produto Controlado

CAS: 524-17-4

Applications Dauricine is a bisbenzylisoquinoline allkaloid derivative that displays a noted number of pharmaceutical properties. It is known to induces severe lung toxicity in animals.
References Xie, H. et al.: Anal. Bioanal. Chem., 408, 4111 (2016);

Fórmula: C₃₈H₄₄N₂O₆

Cor e Forma: Neat

Peso molecular: 624.77

Ref: TR-D194825

Dauricine

CAS: 524-17-4

1.

Fórmula: C₃₈H₄₄N₂O₆

Pureza: 99.24% - 99.75%

Cor e Forma: Solid

Peso molecular: 624.7658

Ref: TM-T6S0119

Dauricine

CAS: 524-17-4

Natural alkaloid

Fórmula: C₃₈H₄₄N₂O₆

Pureza: ≥ 90.0 % (HPLC)

Cor e Forma: Powder

Peso molecular: 624.78

Ref: 5G-80419

Dauricine

CAS: 524-17-4

Dauricine is a natural bisbenzylisoquinoline alkaloid, which is derived from the plant Menispermum dauricum, commonly found in regions of Asia. Its mode of action involves inhibition of various ion channels, notably the calcium and potassium channels, as well as modulation of signaling pathways that influence cell proliferation and apoptosis. These biochemical activities endow Dauricine with the potential to influence cardiovascular, neurological, and oncological outcomes.

Fórmula: C₃₈H₄₄N₂O₆

Pureza: Min. 95%

Cor e Forma: Brown Yellow Powder

Peso molecular: 624.77 g/mol

Ref: 3D-FD66056

Dauricine

CAS: 524-17-4

Fórmula: C₃₈H₄₄N₂O₆

Peso molecular: 624.8

Ref: BE-RMT10620

Dauricine

CAS: 524-17-4

4-(((R)-6,7-Dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-1-yl)methyl)-2-(4-(((R)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-1-yl)methyl)phenoxy)phenol

Fórmula: C₃₈H₄₄N₂O₆

Pureza: 98%

Peso molecular: 624.77

Ref: IN-DG123496

DAURICINE

CAS: 524-17-4

Pureza: 98%

Peso molecular: 624.7780151

Ref: 10-F794658