CAS 53-73-6

angiotensinamida

Descrição:

angiotensinamida, com o número CAS 53-73-6, é um peptídeo que desempenha um papel significativo no sistema renina-angiotensina, que é crucial para regular a pressão arterial e o equilíbrio de fluidos no corpo. É derivado da angiotensina II, um potente vasoconstritor, e está envolvido em vários processos fisiológicos, incluindo a modulação do tônus vascular e a estimulação da secreção de aldosterona das glândulas adrenais. angiotensinamida é caracterizado por sua capacidade de influenciar a função cardiovascular e a homeostase de fluidos. Em termos de sua estrutura química, consiste em uma sequência de aminoácidos que contribuem para sua atividade biológica. A substância é tipicamente estudada no contexto da hipertensão e insuficiência cardíaca, pois pode impactar os mecanismos de regulação da pressão arterial. Suas propriedades farmacológicas a tornam um assunto de interesse na pesquisa cardiovascular, embora não seja comumente usada como agente terapêutico. Compreender suas características é essencial para explorar aplicações potenciais na ciência médica e farmacologia.

Fórmula: C₄₉H₇₀N₁₄O₁₁

InChI: InChI=1/C49H70N14O11/c1-26(2)39(61-42(67)33(12-8-18-55-49(52)53)57-41(66)32(50)23-38(51)65)45(70)58-34(20-29-14-16-31(64)17-15-29)43(68)62-40(27(3)4)46(71)59-35(22-30-24-54-25-56-30)47(72)63-19-9-13-37(63)44(69)60-36(48(73)74)21-28-10-6-5-7-11-28/h5-7,10-11,14-17,24-27,32-37,39-40,64H,8-9,12-13,18-23,50H2,1-4H3,(H2,51,65)(H,54,56)(H,57,66)(H,58,70)(H,59,71)(H,60,69)(H,61,67)(H,62,68)(H,73,74)(H4,52,53,55)/t32-,33-,34-,35-,36-,37-,39-,40-/m0/s1

Chave InChI: JYPVVOOBQVVUQV-CGHBYZBKSA-N

SMILES: CC(C)[C@@H](C(=N[C@@H](Cc1ccc(cc1)O)C(=N[C@@H](C(C)C)C(=N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=N[C@@H](Cc1ccccc1)C(=O)O)O)O)O)O)N=C([C@H](CCCNC(=N)N)N=C([C@H](CC(=N)O)N)O)O

Sinónimos:

• hypertensin II, 1-amide-5-valyl
• asparaginyl-N~5~-(diaminomethylidene)ornithylvalyltyrosylvalylhistidylprolylphenylalanine
• L-asparaginyl-N~5~-(diaminomethylidene)-L-ornithyl-L-valyl-L-tyrosyl-L-valyl-L-histidyl-L-prolyl-L-phenylalanine
• [1-Asparagine-5-valine]-angiotensin II
• 17: PN: WO0144270 SEQID: 20 claimed protein
• 18: PN: WO0143761 SEQID: 20 claimed protein
• 18: PN: WO0155176 SEQID: 20 claimed protein
• 18: PN: WO02087504 SEQID: 20 claimed protein
• 19: PN: WO0002905 SEQID: 20 claimed protein
• 19: PN: WO0198325 SEQID: 20 claimed protein
• 1-Asn2-5-Val-angiotensin II
• 1-Asparagine-5-valineangiotensin II
• 1-Asparaginyl-5-valyl-angiotensin II
• 1-Aspartic acid-5-valine angiotensin II amide
• 1-Aspartic acid-β-amide 5-valine angiotensin II
• 1-L-Asn-5-L-Val-angiotensin II
• 1-L-Asparagine-5-L-valine angiotensin II
• 1-L-Asparagine-5-L-valine-angiotensin
• 1-L-Asparaginyl-5-L-valyl angiotensin octapeptide
• 1-α-Asparagine-5-valine-angiotensin II
• 20: PN: US20030130196 SEQID: 20 claimed protein
• 24: PN: WO9958140 SEQID: 20 claimed protein
• 5-L-Valine-angiotensin II amide
• 5-Valine angiotensin amide II
• 5-Valine angiotensin II amide
• 5-Valine angiotensin II aspartic-β-amide
• 5-Valine-angiotensin II-β-amide
• 5-Valyl angiotensin II amide
• Alanine, N-[1-[N-[N-[N-[N-(N2-L-asparaginyl-L-arginyl)-L-valyl]-L-tyrosyl]-L-valyl]-L-histidyl]-L-prolyl]-3-phenyl-, L-
• Angio Tensinamida
• Angiotensin (Ciba)
• Angiotensin amide
• Angiotensin amide, 5-L-valine-
• Angiotensin II (eel)
• Angiotensin II (Oncorhynchus mykiss)
• Angiotensin II amide
• Angiotensin II amide 5-valine
• Angiotensin II amide, 5-L-valine-
• Angiotensin II aspartic-β-amide, 5-L-valine
• Angiotensin II, 1-L-asparagine-5-L-valine-
• Angiotensin II-5-valine-amide
• Angiotensinamid
• Hypertensin
• Hypertensinamide
• Hypertensine
• Ipertensina
• L-Phenylalanine, N-[1-[N-[N-[N-[N-(N2-L-asparaginyl-L-arginyl)-L-valyl]-L-tyrosyl]-L-valyl]-L-histidyl]-L-prolyl]-
• Nsc 107678
• Rainbow trout angiotensin II
• Val5-angiotensin II amide

(Asn¹,Val⁵)-Angiotensin II

CAS: 53-73-6

Bachem ID: 4027132.

Fórmula: C₄₉H₇₀N₁₄O₁₁

Pureza: 98.7%

Cor e Forma: White Lyophilisate

Peso molecular: 1031.18

Ref: 01-4027132

ASN-ARG-VAL-TYR-VAL-HIS-PRO-PHE

CAS: 53-73-6

ASN-ARG-VAL-TYR-VAL-HIS-PRO-PHE

Fórmula: C₄₉H₇₀N₁₄O₁₁

Pureza: 98%

Peso molecular: 1031.17

Ref: 54-OR1114484

Angiotensin amide

CAS: 53-73-6

Angiotensin amide, an octapeptide amide, can be used to increase blood pressure by vasoconstriction.

Fórmula: C₄₉H₇₀N₁₄O₁₁

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 1031.17

Ref: TM-TP2446

1-Asparagine-5-Valine-Angiotensin II

CAS: 53-73-6

Fórmula: C₄₉H₇₀N₁₄O₁₁

Peso molecular: 1031.19

Ref: 4Z-A-258004

[Asn1,Val5]-Angiotensin II

CAS: 53-73-6

[Asn1,Val5]-Angiotensin II is a peptide that is used as a research tool to study the effects of angiotensin II on ion channels, ligand-receptor interactions and protein interactions. It is also used as an antibody to measure the level of angiotensin II in cells. This peptide has been shown to be an activator of potassium channels and inhibits calcium channels. The high purity of this product makes it suitable for use in pharmacology and cell biology research.

Fórmula: C₄₉H₇₀N₁₄O₁₁

Pureza: Min. 95%

Peso molecular: 1,031.2 g/mol

Ref: 3D-PAN-4036-V

H-Asn-Arg-Val-Tyr-Val-His-Pro-Phe-OH

CAS: 53-73-6

H-Asn-Arg-Val-Tyr-Val-His-Pro-Phe (HAV) is a small molecule that is a member of the ubiquitin ligase family. This drug has been shown to have a variety of biological effects, including cardiac and bowel disease, as well as hypertension. HAV has also been shown to reduce the risk of heart failure in people with chronic kidney disease. HAV binds to the protein PCSK9 and inhibits its function by binding to the epsilon site on PCSK9. This leads to an increase in low density lipoprotein cholesterol and a decrease in high density lipoprotein cholesterol levels. HAV also has an amide group that allows it to inhibit angiotensin II and act as a pressor agent.

Fórmula: C₄₉H₇₀N₁₄O₁₁

Pureza: Min. 95%

Peso molecular: 1,031.17 g/mol

Ref: 3D-FA109691