CAS 54024-22-5

Desogestrel

Descrição:

Desogestrel é um progestágeno sintético, utilizado principalmente em contraceptivos hormonais. É caracterizado pela sua capacidade de imitar o hormônio natural progesterona, regulando assim a ovulação e os ciclos menstruais. Desogestrel é conhecido por sua alta biodisponibilidade oral e frequentemente é combinado com estrogênio em pílulas anticoncepcionais orais combinadas. Sua estrutura química apresenta um anel de ciclopropano, o que contribui para sua estabilidade e eficácia. A substância é lipofílica, permitindo que seja bem absorvida no trato gastrointestinal. Desogestrel tem uma meia-vida relativamente longa, o que apoia seu uso em regimes contraceptivos diários. Além disso, apresenta atividade androgênica mínima, tornando-se uma escolha preferida para indivíduos que podem experimentar efeitos colaterais de progestágenos mais androgênicos. O perfil farmacológico de Desogestrel inclui efeitos no endométrio, muco cervical e supressão da ovulação, tornando-o eficaz na prevenção da gravidez. Assim como qualquer medicamento, potenciais efeitos colaterais e contraindicações devem ser considerados, e é essencial consultar profissionais de saúde para obter aconselhamento personalizado.

Fórmula: C₂₂H₃₀O

InChI: InChI=1S/C22H30O/c1-4-21-14-15(3)20-17-9-7-6-8-16(17)10-11-18(20)19(21)12-13-22(21,23)5-2/h2,8,17-20,23H,3-4,6-7,9-14H2,1H3/t17-,18-,19-,20+,21-,22-/m0/s1

Chave InChI: InChIKey=RPLCPCMSCLEKRS-BPIQYHPVSA-N

SMILES: C(C)[C@@]12[C@]([C@]3([C@](C(=C)C1)([C@@]4(C(CC3)=CCCC4)[H])[H])[H])(CC[C@]2(C#C)O)[H]

Sinónimos:

• (+)-13β-Ethyl-17α-ethynyl-11-methylenegon-4-en-17β-ol
• (17a)-13-Ethyl-11-methylene-18,19-dinorpregn-4-en-20-yn-17-ol
• (17alpha)-13-Ethyl-11-methylene-18,19-dinorpregn-4-en-20-yn-17-ol
• (8S,9S,10R,13S,14S,17R)-13-Ethyl-17-ethynyl-11-methylene-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-ol (non-preferred name)
• (8S,9S,10R,13S,14S,17R)-13-ethyl-17-ethynyl-11-methylidene-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-ol
• (8S,9S,10R,13S,14S,17R)-13-ethyl-17-ethynyl-11-methylidene-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-ol (non-preferred name)
• (8S,9S,10R,13S,14S,17R)-17-Ethinyl-13-ethyl-11-methyliden-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-ol
• 13-Ethyl-11-methylene-18,19-dinor-17α-4-pregnen-20-yn-17-ol
• 17-Ethynyl-18-methyl-11-methyleneestr-4-en-17β-ol
• 17a-Ethynyl-18-methyl-11-methyl-ene-D4-estren-17b-ol
• 18,19-Dinorpregn-4-en-20-yn-17-ol, 13-ethyl-11-methylene-, (17α)-
• 258-929-4
• Cerazette
• Cyclosa
• Dicromil
• Marvelon 150/320
• Org 2969
• DESOGESTREL
• org2969
• 18,19-Dinorpregn-4-en-20-yn-17-ol, 13-ethyl-11-methylene-, (17.alpha.)-
• (8S,9S,10R,13S,14S,17R)-13-ethyl-17-ethynyl-11-Methylene-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-ol
• (17R)-13-Ethyl-11-methylene-18,19-dinorpregn-4-en-20-yn-17-ol
• 13-ethyl-11-methylene-18,19-dinor-17alpha-pregn-4-en-20-yn-17-ol
• DESOGESTRAL
• (17β)-13-Ethyl-11-methylene-19-nor-pregn-4-en-20-yn-17-ol
• Desogestrel for system suitability, European Pharmacopoeia (EP) Reference Standard
• 13-ethyl-11-methylene-19-dinorpregn-4-en-20-yn-17-o(17-alpha)-1
• (8S,9S,10R,13S,14S,17R)-13-ethyl-17-ethynyl-11-methylene-1,2,3,6,7,8,9,10,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-ol
• DESTODENE
• Desogestrel (50 mg)

Desogestrel

CAS: 54024-22-5

Fórmula: C₂₂H₃₀O

Pureza: >98.0%(HPLC)

Cor e Forma: White to Almost white powder to crystal

Peso molecular: 310.48

Ref: 3B-D4163

Desogestrel

CAS: 54024-22-5

Desogestrel

Fórmula: C₂₂H₃₀O

Pureza: 99.8%

Cor e Forma: White To Off-White

Peso molecular: 310.22967

Ref: 47-568

DESOGESTREL CRS

CAS: 54024-22-5

DESOGESTREL CRS

Fórmula: C₂₂H₃₀O

Cor e Forma: Crystalline Powder. White. Powder.

Peso molecular: 310.473

Ref: 41-Y0000509

DESOGESTREL FOR SYSTEM SUITABILITY CRS

CAS: 54024-22-5

DESOGESTREL FOR SYSTEM SUITABILITY CRS

Fórmula: C₂₂H₃₀O

Peso molecular: 310.473

Ref: 41-Y0000510

Desogestrel

CAS: 54024-22-5

Estrogens and progestins

Fórmula: C₂₂H₃₀O

Cor e Forma: White Crystalline Powder

Peso molecular: 310.22967

Ref: 45-1173235

Desogestrel

CAS: 54024-22-5

Desogestrel

Fórmula: C₂₂H₃₀O

Pureza: 99.5%

Cor e Forma: Solid

Peso molecular: 310.47

Ref: 54-BUP11759

Desogestrel

CAS: 54024-22-5

Desogestrel

Fórmula: C₂₂H₃₀O

Pureza: >98%

Peso molecular: 310.48

Ref: 54-OR1025609

Desogestrel

CAS: 54024-22-5

Fórmula: C₂₂H₃₀O

Cor e Forma: White To Off-White Solid

Peso molecular: 310.48

Ref: 4Z-D-167

Desogestrel

CAS: 54024-22-5

Fórmula: C₂₂H₃₀O

Cor e Forma: White To Off-White

Peso molecular: 310.47

Ref: 61-FOR1024.00

Desogestrel

CAS: 54024-22-5

Fórmula: C₂₂H₃₀O

Cor e Forma: Neat

Peso molecular: 310.47

Ref: 86-MM1024.00

Desogestrel

Produto Controlado

CAS: 54024-22-5

Fórmula: C₂₂H₃₀O

Cor e Forma: Neat

Peso molecular: 310.47

Ref: 04-C12170120

13-ethyl-17-ethynyl-11-methylene-1,2,3,6,7,8,9,10,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-ol;(17α)-13-Ethyl-11-methylene-18,19-dinorpregn-4-en-20-yn-17-o

CAS: 54024-22-5

Fórmula: C₂₂H₃₀O

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 310.4730

Ref: IN-DA003P9R

Desogestrel-13C2,d2 (Major)

Produto Controlado

CAS: 54024-22-5

Applications A labelled progestogen with low androgenic potency.
References Viinikka, L., et al.: Eur. J. Clin. Pharmacol., 15, 349 (1979), Bergink, E.W., et al.: J. Steroid Biochem., 14, 175 (1981)

Fórmula: C₂₀₁₃C₂H₂₈D₂O

Cor e Forma: Neat

Peso molecular: 314.47

Ref: TR-D296877

Desogestrel

Produto Controlado

CAS: 54024-22-5

Applications A progestogen with low androgenic potency.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Viinikka, L., et al.: Eur. J. Clin. Pharmacol., 15, 349 (1979), Bergink, E.W., et al.: J. Steroid Biochem., 14, 175 (1981)

Fórmula: C₂₂H₃₀O

Cor e Forma: Neat

Peso molecular: 310.47

Ref: TR-D296875

Desogestrel

CAS: 54024-22-5

Fórmula: C₂₂H₃₀O

Pureza: (HPLC) ≥ 98.0%

Cor e Forma: White to almost white powder

Peso molecular: 310.47

Ref: 7W-GP5321

Desogestrel

CAS: 54024-22-5

Desogestrel (Cerazette) is a synthetic progestational hormone used often as the progestogenic component of combined oral contraceptive agents.

Fórmula: C₂₂H₃₀O

Pureza: 99.8% - 99.95%

Cor e Forma: Crystals Solid

Peso molecular: 310.473

Ref: TM-T6819

Desogestrel

CAS: 54024-22-5

Fórmula: C₂₂H₃₀O

Cor e Forma: Solid

Peso molecular: 310.5

Ref: BE-RMCD073000

Desogestrel

CAS: 54024-22-5

Fórmula: C₂₂H₃₀O

Peso molecular: 310.5

Ref: ST-EA-CP-D35000

Desogestrel

Produto Controlado

CAS: 54024-22-5

Desogestrel is a progestin that is often used in combination with ethinyl estradiol in oral contraceptives. It has been shown to reduce ovarian activity and has a high level of resistance to metabolism by cytochrome P450 enzymes. Desogestrel has been widely used for the treatment of inflammatory lesions, such as those found on the skin or in the mouth, but it does not have any therapeutic effects against inflammation in other parts of the body. Desogestrel is an active metabolite of nomegestrol acetate, which has been shown to have anti-inflammatory properties. The effect of desogestrel on inflammatory lesions may be due to its ability to inhibit prostaglandin synthesis and its anti-inflammatory effects.

Fórmula: C₂₂H₃₀O

Pureza: Min. 98 Area-%

Peso molecular: 310.47 g/mol

Ref: 3D-FD21372